Additional file 6: Figure S6. of The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

Showing association between age of onset and onset of symptoms within RA patients of the Leiden EAC. (a) Results of logistic regression analyses of age at RA onset in relation to the onset of symptoms. OR of 1.01 indicates that per 1-year increase in the age of onset, the odds of having (sub)acute onset increase 1%. This reflects 12% (1.0110) per 10-year increase in age of onset and 25% (1.0120) per 20-year increase in age of onset. (b) Proportion of RA patients with (sub)acute onset of symptoms in three age groups (p = 0.003). Number of patients per age group: <40, n = 181; 40–60, n = 466; >60, n = 537. (TIF 2476 kb

Selected weight management interventions for military populations in the United States: a narrative report.

Overweight and obesity continues to be a significant public health burden in the US and particularly among military personnel. Although the US Department of Defense mandates standardized physical activity requirements for military members, incidence and prevalence of overweight and obesity among military personnel continue to increase. Each military department controls their own interventional strategies for physical fitness and weight control. However, unique challenges such as geographic transients, lack of central standardization and empirical efficacy data across military departments, and chronic stress associated with military service adversely affect program outcomes. This brief narrative report explores overweight and obesity interventions among military populations from 2006 to 2016 and includes programmatic reviews of eight overweight and obesity interventions: The Prevention of Obesity in Military Community; Health Eating, Activity, and Lifestyle Training Headquarters (H.E.A.L.T.H); ArmyMOVE!; L.I.F.E.; Look AHEAD; Nutrition-focused Wellness Coaching; Go for Green; and LE3AN. A majority of these interventions did not report significant weight loss 6 months post intervention, and did not mention a theoretical foundation within the interventions. Further research to examine the importance of theory-based programming is warranted to improve process and outcome objectives

Additional file 3: of Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study

Table presenting biological interaction analysis between HLA-DRB1 SE alleles and smoking with the number of autoantibodies in the NOAR and the EAC. (DOCX 17 kb