Operation of the cryogenic system for the Mirror Fusion Test Facility

The cryogenic system for the Mirror Fusion Test Facility (MFTF) at Lawrence Livermore National Laboratory (LLNL) was designed to cool the entire MFTF-B system from ambient to operating temperature in less than 10 days. The system was successfully operated in the recent plant and capital equipment (PACE) acceptance tests, and results from these tests helped us correct problem areas and improve the system

The Mirror Fusion Test Facility cryogenic system: Performance, management approach, and present equipment status

The cryogenic system for the Mirror Fusion Test Facility (MFTF) is a 14-kW, 4.35-K helium refrigeration system that proved to be highly successful and cost-effective. All operating objectives were met, while remaining within a few percent of initial cost and schedule plans. The management approach used in MFTF allowed decisions to be made quickly and effectively, and it helped keep costs down. Manpower levels, extent and type of industrial participation, key aspects of subcontractor specifications, and subcontractor interactions are reviewed, as well as highlights of the system tests, operation, and present equipment status. Organizations planning large, high-technology systems may benefit from this experience with the MFTF cryogenic system

Recommendations for a cryogenic system for ITER (International Thermonuclear Experimental Reactor)

The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Japan, the European Community, the Soviet Union, and the United States. ITER will be a large machine requiring up to 100 kW of refrigeration at 4.5 K to cool its superconducting magnets. Unlike earlier fusion experiments, the ITER cryogenic system must handle pulse loads constituting a large percentage of the total load. These come from neutron heating during a fusion burn and from ac losses during ramping of current in the PF (poloidal field) coils. This paper presents a conceptual design for a cryogenic system that meets ITER requirements. It describes a system with the following features: Only time-proven components are used. The system obtains a high efficiency without use of cold pumps or other developmental components. High reliability is achieved by paralleling compressors and expanders and by using adequate isolation valving. The problem of load fluctuations is solved by a simple load-leveling device. The cryogenic system can be housed in a separate building located at a considerable distance from the ITER core, if desired. The paper also summarizes physical plant size, cost estimates, and means of handling vented helium during magnet quench. 4 refs., 4 figs., 3 tabs

Analysis of quench-vent pressures for present design of ITER (International Thermonuclear Experimental Reactor) TF (toroidal field) coils

The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Japan, the European Community, the Union of the Soviet Union, and the United States. This paper examines the effects of a quench within the toroidal field (TF) coils based on current ITER design. It is a preliminary, rough analysis. Its intent is to assist ITER designers while more accurate computer codes are being developed and to provide a check against these more rigorous solutions. Rigorous solutions to the quench problem are very complex involving three- dimensional heat transfer, extreme changes in heat capacities and copper resistivity, and varying flow dynamics within the conductors. This analysis addresses all these factors in an approximate way. The result is much less accurate than a rigorous analysis. Results here could be in error as much as 30 to 40 percent. However, it is believed that this paper can still be very useful to the coil designer. Coil pressures and temperatures vs time into a quench are presented. Rate of helium vent, energy deposition in the coil, and depletion of magnetic stored energy are also presented. Peak pressures are high (about 43 MPa). This is due to the very long vent path length (446 m), small hydraulic diameters, and high current densities associated with ITER's cable-in-conduit design. The effects of these pressures as well as the ability of the coil to be self protecting during a quench are discussed. 3 refs., 1 fig., 3 tabs

A cryogenic system design for the international thermonuclear experimental reactor (ITER)

A conceptual design for ITER was completed last year. The author developed a suitable cryogenic system for ITER as part of this conceptual design effort. An overview of the design is reported. Emphasis is on the fact that cryogenics is a mature science, and a system supporting ITER needs can be made from time-proven components without loss of efficiency or reliability. Because of the large size of the ITER cryogenic system, large numbers of compressors and expanders must be used. Very high reliability is assured by arranging these components in parallel banks where servicing of individual components can be done without interruption of operations. This and other ideas based on the author's experience with Mirror Fusion Test Facility (MFTF) operations are described. 5 refs., 3 figs

The cryogenic helium cooling system for the Tokamak physics experiment

The Tokamak Physics Experiment (TPX) will use supercritical helium to cool all the magnets and supply helium to the Vacuum cryopumping subsystem. The heat loads will come from the standard steady state conduction and thermal radiation sources and from the pulsed loads of the nuclear and eddy currents caused by the Central Solenoid Coils and the plasma positioning coils. The operations of the TPX will begin with pulses of up to 1000 seconds in duration every 75 minutes. The helium system utilizes a pulse load leveling scheme to buffer out the effects of the pulse load and maintain a constant cryogenic plant operation. The pulse load leveling scheme utilizes the thermal mass of liquid and gaseous helium stored in a remote dewar to absorb the pulses of the tokamak loads. The mass of the stored helium will buffer out the temperature pulses allowing 5 K helium to be delivered to the magnets throughout the length of the pulse. The temperature of the dewar will remain below 5 K with all the energy of the pulse absorbed. This paper will present the details of the heat load sources, of the pulse load leveling scheme operations, a partial helium schematic, dewar temperature as a function of time, the heat load sources as a function of time and the helium temperature as a function of length along the various components that will be cooled

Involvement of the Fcγ receptor in a chronic N-methyl-4-phenyl-1,,2, 3,6-tetrahydropyridine mouse model of dopaminergic loss

Although there is growing evidence for a role of the innate immune response in Parkinson's disease, the nature of any humoral response in dopaminergic degeneration is uncertain. Here we report on a protracted N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of dopaminergic death that potentially allows a more full adaptive humoral response to develop. Rag2 mutant mice that lack the full adaptive response (deficient in both T and B cells) are resistant to dopaminergic death and behavioral deficiencies in this model. These mice are resensitized after reconstitution with WT splenocytes. To more directly provide evidence for humoral/IgG involvement, we show that deficiency of Fcγ receptors, which are critical for activation of macrophages/microglia by binding to IgGs, is also protective in this protracted model. FcγR-deficient mice display improved behavior and impaired microglial activation. Interestingly, however, Rag2 mutant but not FcγR-deficient mice are resistant to a more standard N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine paradigm where death is more rapid. Taken together, these data indicate that, provided sufficient time, the humoral arm of the adaptive immune system can play a critical functional role in modulating the microglial response to dopaminergic degeneration and suggest that this humoral component may participate in degeneration in Parkinson's disease