Self-assembly of iron nanoclusters on the Fe3O4(111) superstructured surface

We report on the self-organized growth of a regular array of Fe nanoclusters on a nanopatterned magnetite surface. Under oxidizing preparation conditions the (111) surface of magnetite exhibits a regular superstructure with three-fold symmetry and a 42 A periodicity. This superstructure represents an oxygen terminated (111) surface, which is reconstructed to form a periodically strained surface. This strain patterned surface has been used as a template for the growth of an ultrathin metal film. A Fe film of 0.5 A thickness was deposited on the substrate at room temperature. Fe nanoclusters are formed on top of the surface superstructure creating a regular array with the period of the superstructure. We also demonstrate that at least the initial stage of Fe growth occurs in two-dimensional mode. In the areas of the surface where the strain pattern is not formed, random nucleation of Fe was observed.Comment: 6 pages, 3 figure

Social cognition and its influence on adaptation of people who suffered from the first psychotic episode of schizophrenia

Goal of research is verification of social intelligence characteristics and social intelligence influence on adaptation of people diagnosed with schizophrenia suffered from the first psychotic episode in order to elaborate recommendations relating psychosocial treatment and rehabilitatio

Social cognition and its influence on adaptation of people who suffered from the first psychotic episode of schizophrenia

Social cognition covers different fields that include a human ability to recognize and identify emotions, apperceive mental states and intentions, understand roles, rules and aims that are a base of social interaction. Disorder in these abilities of people diagnosed with schizophrenia may cause social dysfunction

Oxide nanotemplates for self-assembling "solid" building blocks

It is widely accepted that self-assembling building blocks is one of the promising ways for engineering new materials. Recent years reveal substantial progress in fabricating colloidal particles, polymer blocks and supramolecular aggregates of organic molecules. Despite of substantial progress in molecular self-assembly there is still a lack of simple blocks made of "solid matter" (e.g. metals, oxides etc.) with well-defined crystal structure and spatial order. Here we demonstrate that ordered arrays of metal nanoclusters can be fabricated by self-assembly on a wide range of oxide templates. These nano-templates are produced either by depositing an alien oxide film or by oxidizing a metal/metal oxide substrate.Comment: 11 pages, 2 figures added DFT calculations and Fig.

Синтез новых 3’-N-ацильных и 3’-N-алкильных производных 3’-амино-3’-дезокситимидина

A number of new 3'-N-alcyl and 3'-N-alkyl derivatives of 3'-amino-3'-deoxythymidine was obtained by means of nucleoside and carboxylic acids condensation. Also new 3'-N-alkyl derivatives of 3'-amino-3'-deoxythymidine was obtained by means of nucleoside alkylation with esters of a,b-unsaturated carboxylic acidsПолучен ряд новых 3’-N-ацильных производных 3’-амино-3’-дезокситимидина путем конденсации нуклеозида с карбоновыми кислотами, а также проведено его алкилирование эфирами ?,?-ненасыщенных карбоновых кислот с получением новых 3’-N-алкильных производных.

A new view of electrochemistry at highly oriented pyrolytic graphite

Major new insights on electrochemical processes at graphite electrodes are reported, following extensive investigations of two of the most studied redox couples, Fe(CN)64–/3– and Ru(NH3)63+/2+. Experiments have been carried out on five different grades of highly oriented pyrolytic graphite (HOPG) that vary in step-edge height and surface coverage. Significantly, the same electrochemical characteristic is observed on all surfaces, independent of surface quality: initial cyclic voltammetry (CV) is close to reversible on freshly cleaved surfaces (>400 measurements for Fe(CN)64–/3– and >100 for Ru(NH3)63+/2+), in marked contrast to previous studies that have found very slow electron transfer (ET) kinetics, with an interpretation that ET only occurs at step edges. Significantly, high spatial resolution electrochemical imaging with scanning electrochemical cell microscopy, on the highest quality mechanically cleaved HOPG, demonstrates definitively that the pristine basal surface supports fast ET, and that ET is not confined to step edges. However, the history of the HOPG surface strongly influences the electrochemical behavior. Thus, Fe(CN)64–/3– shows markedly diminished ET kinetics with either extended exposure of the HOPG surface to the ambient environment or repeated CV measurements. In situ atomic force microscopy (AFM) reveals that the deterioration in apparent ET kinetics is coupled with the deposition of material on the HOPG electrode, while conducting-AFM highlights that, after cleaving, the local surface conductivity of HOPG deteriorates significantly with time. These observations and new insights are not only important for graphite, but have significant implications for electrochemistry at related carbon materials such as graphene and carbon nanotubes

Синтез и характеристика фотоактивных арилазидных производных пептидов семакса и Pro-Gly-Pro

The photoaffine arylazide derivatives of peptides semax and Pro-Gly-Pro have been synthesized. It was shown that these compounds have cytoptotective action in culture of PC12 cells under conditions of oxidative stress.Осуществлен синтез п-азидотетрафторбензойных производных пептидов семакса и Pro-Gly-Pro. Показано, что полученные фотоаффинные арилазидные зонды обладают цтопротективным действием на культивируемые клетки PC12 в условиях окислительного процесс

Липосомальные системы доставки биологически активных соединений в лечении некоторых заболеваний

Based on the aggregate results from several different studies, this article will provide readers a survey view about the ability to drug delivery one of the most typical nano structures – liposome and the use of this structure for various therapeutic purposes, including anticancer therapy, antibacterial therapy and gene therapy.Липосомы являются одной из самых перспективных систем доставки лекарственных веществ в органы и ткани благодаря их особым свойствам - биосовместимости, мембранотропности, способности к пассивному нацеливанию и возможности включения как гидрофильных, так и гидрофобных структур. В настоящем обзоре в краткой форме приведены обобщенные данные, относящиеся к разработкам и исследованиям липосомальных средств доставки лекарственных субстанций, применяющихся в медицинских целях