5 research outputs found

    <span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Synthetic potentiality of novel <i style="mso-bidi-font-style:normal">N</i>-methyl isoxazolidines in the synthesis of 1,3-amino alcohols under microwave irradiation</span>

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    1145-1150Microwave assisted N-O bond cleavage of novel N-methyl isoxazolidines under mild conditions have been studied and found to afford 1,3-amino alcohols readily with high yield in a short reaction time

    Microwave assisted green synthesis of novel spiro isoxazolidine derivatives with α-chloro nitrones

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    525-530Microwave assisted 1,3-dipolar cycloaddition reaction of -chloro nitrones to novel -N-methyl and -N-phenylfuran derivative affords exclusively single regioselective 5-spiro isoxazolidines while the same reaction with -methylene--butyrolactone affords two diastereomeric 5-spiro isoxazolidines with high selectivity

    <span style="font-size:12.0pt;font-family: "Times New Roman";mso-fareast-font-family:"Times New Roman";mso-ansi-language: EN-GB;mso-fareast-language:EN-US;mso-bidi-language:AR-SA" lang="EN-GB">Green synthesis of novel isoxazoline derivatives using <i style="mso-bidi-font-style:normal">N</i>-methyl-α-chloro nitrone and their antibacterial activities </span>

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    1180-1185Microwave assisted 1,3-dipolar cycloaddition reaction of N-methyl-α-chloro nitrone with various alkynes as dipolarophile have been studied and found to afford diastereomeric novel isoxazoline derivatives with high selectivity. All the synthesized compounds have been screened for their antibacterial activity and are found to exihibit significant activity
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