Nonlinear Optics as a Detection Scheme for Biomimetic Sensors:

Vibrational spectra of biomimetic membranes have been obtained using a broad-band approach to sum frequency generation (SFG). A new innovation, broad band SFG (BBSFG) allows for high quality SFG spectra with rapid collection times. With the BBSFG approach, we have followed in situ the formation of a hybrid bilayer membrane (HBM) from the reorganization of phospholipid vesicles at akanethiol monolayers