445 research outputs found
2-(5-Fluoro-3-isopropylÂsulfanyl-7-methyl-1-benzofuran-2-yl)acetic acid
The title compound, C14H15FO3S, was prepared by alkaline hydrolysis of ethyl 2-(5-fluoro-3-isopropylÂsulfanyl-7-methyl-1-benzofuran-2-yl)acetate. In the crystal, molÂecules are linked via pairs of O—H⋯O hydrogen bonds, forming inversion dimers. These dimers are connected by weak C—H⋯O hydrogen bonds
3-(3-ChloroÂphenylÂsulfinÂyl)-2,4,6-trimethyl-1-benzofuran
In the title compound, C17H15ClO2S, the 3-chloroÂphenyl ring makes a dihedral angle of 71.46 (4)° with the mean plane of the benzofuran fragment. In the crystal, molÂecules are linked by weak C—H⋯O hydrogen bonds and a slipped π–π interÂaction between the 3-chloroÂphenyl rings of adjacent molÂecules [centroid–centroid distance = 3.630 (2) Å, interÂplanar distance = 3.375 (2) Å and slippage = 1.337 (2) Å]
2-(3-FluoroÂphenÂyl)-5-iodo-7-methyl-3-methylÂsulfinyl-1-benzofuran
In the title compound, C16H12FIO2S, the 3-fluoroÂphenyl ring makes a dihedral angle of 34.93 (7)° with the mean plane [r.m.s. deviation = 0.019 (1) Å] of the benzofuran fragment. In the crystal, molÂecules are linked via pairs of I⋯O contacts [3.088 (2) Å] into inversion dimers. These dimers are connected by weak C—H⋯O hydrogen bonds
3-(3-ChloroÂphenylÂsulfonÂyl)-2,5,7-trimethyl-1-benzofuran
In the title compound, C17H15ClO3S, the 3-chloroÂphenyl ring makes a dihedral angle of 77.76 (6)° with the mean plane [r.m.s. deviation = 0.007 (1) Å] of the benzofuran fragment. In the crystal, molÂecules are linked by weak interÂmolecular C—H⋯O and C—H⋯π interÂactions
2-Methyl-3-(phenylÂsulfonÂyl)naphtho[1,2-b]furan
In the title molÂecule, C19H14O3S, the phenyl ring forms a dihedral angle of 69.13 (6)° with the plane of the naphthofuran fragment, being slightly tilted towards it. The crystal packing exhibits π–π interÂactions between the benzene rings from neighbouring molÂecules [centroid–centroid distance = 3.616 (4) Å] and weak C—H⋯O and C—H⋯π interÂactions
2-(5-CycloÂhexyl-3-methylÂsulfanyl-1-benzofuran-2-yl)acetic acid
In the title compound, C17H20O3S, the cycloÂhexyl ring adopts a chair conformation. In the crystal, the carboxyl groups are involved in interÂmolecular O—H⋯O hydrogen bonds, which link the molÂecules into centrosymmetric dimers. These dimers are further stabilized by weak interÂmolecular C—H⋯O hydrogen bonds. In addition, the crystal structure also exhibits aromatic π–π interÂactions between the furan rings of adjacent molÂecules [centroid–centroid distance = 3.505 (2) Å, interÂplanar distance = 3.385 (2) Å and slippage = 0.909 (2) Å], and interÂmolecular C—H⋯π interÂactions
2-(4-FluoroÂphenÂyl)-1-(phenylÂsulfinÂyl)ÂnaphthoÂ[2,1-b]furan
In the title compound, C24H15FO2S, the 4-fluoroÂphenyl ring makes a dihedral angle of 19.43 (4)° with the mean plane of the naphthoÂfuran fragment. The dihedral angle between the phenyl ring and the mean plane of the naphthoÂfuran fragment is 85.83 (4)°. In the crystal, molÂecules are linked by weak interÂmolecular C—H⋯O hydrogen bonds
2-(3-EthylÂsulfanyl-5-phenyl-1-benzofuran-2-yl)acetic acid
The title compound, C18H16O3S, crystallizes with two symmetry-independent molÂecules in the asymmetric unit. The phenyl rings are rotated out of the benzofuran planes, making dihedral angles of 43.38 (7) and 56.13 (6)° in the two molÂecules. The carboxyl groups are involved in inversion-related interÂmolecular O—H⋯O hydrogen bonds, which link the molÂecules into centrosymmetric dimers. These dimers are further packed into stacks along the b axis by weak non-classical interÂmolecular C—H⋯O hydrogen bonds. The crystal structure also exhibits interÂmolecular C—H⋯π interÂactions, and two aromatic π–π interÂactions between the furan rings of neighbouring benzofuran systems; the centroid–centroid distances are 3.500 (3) and 3.605 (3) Å
Methyl 2-(5-methyl-3-methylÂsulfinyl-1-benzofuran-2-yl)acetate
The title compound, C13H14O4S, was prepared by oxidation of methyl 2-(5-methyl-3-methylÂsulfanyl-1-benzofuran-2-yl)acetate with 3-chloroÂperoxyÂbenzoic acid. The O atom and methyl group of the methylÂsulfinyl substituent lie on opposite sides of the plane of the benzofuran system. The crystal structure is stabilized by interÂmolecular aromatic π–π interÂactions between the benzene rings of neighbouring molÂecules, with a centroid–centroid separation of 3.841 (3) Å
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