Cell seeding chamber for bone graft substitutes

There is an increasing demand for bone graft substitutes that are used as osteoconductive scaffolds in the treatment of bone defects and fractures. Achieving optimal bone regeneration requires initial cell seeding of the scaffolds prior to implantation. The cell seeding chamber is a closed assembly. It works like a sandglass. The position of the scaffold is between two reservoirs containing the fluid (e. g. blood). The fluid at the upper reservoir flows through the scaffold driven by gravity. Fluid is collected at the lower reservoir. If the upper reservoir is empty the whole assembly turned and the process starts again. A new compact cell seeding chamber for initial cell seeding has been developed that can be used in the operating theater

New computer system simplifies programming of mathematical equations

Automatic Mathematical Translator /AMSTRAN/ permits scientists or engineers to enter mathematical equations in their natural mathematical format and to obtain an immediate graphical display of the solution. This automatic-programming, on-line, multiterminal computer system allows experienced programmers to solve nonroutine problems

Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles

Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal antibody against β‐MSP were used for immunocytochemical detection of the respective antigens in different organs from different species. SG immunoreactivity was detected in the epithelium of the pubertal and adult human and in monkey seminal vesicle, ampulla of the vas deferens, and ejaculatory duct. PAP, β‐MSP, and PSA immunoreactivities were detected in the pubertal and adult human prostate and the cranial and caudal monkey prostate. With the exception of a weak PSA immunoreactivity in the proximal portions of the ejaculatory duct, none of the latter antisera reacted with seminal vesicle, ampullary, and ejaculatory duct epithelium. Among the non‐primate species studied (dog, bull, rat, guinea pig) only the canine prostatic epithelium displayed a definite immunoreactivity with the PAP antibody and a moderate reaction with the PSA antibody. No immunoreaction was seen in bull and rat seminal vesicle and canine ampulla of the vas deferens with the SG antibody. The same was true for the (ventral) prostate of rat, bull, and dog for β‐MSP. The epithelium of the rat dorsal prostate showed a slight cross‐reactivity with the monoclonal antibody against β‐MSP and one polyclonal antibody against PSA. The findings indicate a rather strict species‐dependent expression of human seminal proteins which show some similarities in primates, but only marginal relationship to species with different physiology of seminal fluid

Microlensing events from the 11-year observations of the Wendelstein Calar Alto Pixellensing Project

We present the results of the decade-long M31 observation from the Wendelstein Calar Alto Pixellensing Project (WeCAPP). WeCAPP has monitored M31 from 1997 till 2008 in both R- and I-filters, thus provides the longest baseline of all M31 microlensing surveys. The data are analyzed with the difference imaging analysis, which is most suitable to study variability in crowded stellar fields. We extracted light curves based on each pixel, and devised selection criteria that are optimized to identify microlensing events. This leads to 10 new events, and sums up to a total of 12 microlensing events from WeCAPP, for which we derive their timescales, flux excesses, and colors from their light curves. The color of the lensed stars fall between (R-I) = 0.56 to 1.36, with a median of 1.0 mag, in agreement with our expectation that the sources are most likely bright, red stars at post main-sequence stage. The event FWHM timescales range from 0.5 to 14 days, with a median of 3 days, in good agreement with predictions based on the model of Riffeser et al. (2006).Comment: 44 pages, 16 figures, 5 tables. ApJ accepte

Inter-University Centre in Dubrovnik: 50 years of fostering science without borders

Its location at the Mediterranean Sea, the welcome character of its landscape and people, and over 2000 years of its rich history make Croatia one of the most privileged countries in Europe. Croatia is also the home of a special academic jewel: the Inter-University Centre (IUC) in Dubrovnik. The IUC is an independent university center established by a network of international universities with an aim to promote academic cooperation. It was founded in 1972 by 30 universities under the leadership of Ivan Supek, an outstanding physicist, survivor of a Gestapo prison, and later dean of the University of Zagreb. Two founding directors – Orjar Oyen, professor in sociology at University Bergen and Peter Fischer-Appelt, president of the University of Hamburg – have remained cordially associated to the IUC. The building where the center is located, former Don Frane Bulić high school, was donated by the City of Dubrovni

Behavior of heuristics and state space structure near SAT/UNSAT transition

We study the behavior of ASAT, a heuristic for solving satisfiability problems by stochastic local search near the SAT/UNSAT transition. The heuristic is focused, i.e. only variables in unsatisfied clauses are updated in each step, and is significantly simpler, while similar to, walksat or Focused Metropolis Search. We show that ASAT solves instances as large as one million variables in linear time, on average, up to 4.21 clauses per variable for random 3SAT. For K higher than 3, ASAT appears to solve instances at the ``FRSB threshold'' in linear time, up to K=7.Comment: 12 pages, 6 figures, longer version available as MSc thesis of first author at http://biophys.physics.kth.se/docs/ardelius_thesis.pd