3,269 research outputs found
Tensors, monads and actions
We exhibit sufficient conditions for a monoidal monad T on a monoidal
category C to induce a monoidal structure on the Eilenberg--Moore category C^T
that represents bimorphisms. The category of actions in C^T is then shown to be
monadic over the base category C.Comment: v4: Minor corrections; added dedicatio
Whole-grain foods and chronic disease: evidence from epidemiological and intervention studies
Cereal-based foods are key components of the diet and they dominate most food-based dietary recommendations in order to achieve targets for intake of carbohydrate, protein and dietary fibre. Processing (milling) of grains to produce refined grain products removes key nutrients and phytochemicals from the flour and although in some countries nutrients may be replaced with mandatory fortification, overall this refinement reduces their potential nutritional quality. There is increasing evidence from both observational and intervention studies that increased intake of less-refined, whole-grain (WG) foods has positive health benefits. The highest WG consumers are consistently shown to have lower risk of developing CVD, type 2 diabetes and some cancers. WG consumers may also have better digestive health and are likely to have lower BMI and gain less weight over time. The bulk of the evidence for the benefits of WG comes from observational studies, but evidence of benefit in intervention studies and potential mechanisms of action is increasing. Overall this evidence supports the promotion of WG foods over refined grain foods in the diet, but this would require adoption of standard definitions of 'whole grain' and 'whole-grain foods' which will enable innovation by food manufacturers, provide clarity for the consumer and encourage the implementation of food-based dietary recommendations and public health strategies
General practice registrars’ intentions for future practice: Implications for rural medical workforce planning
The models of practice that general practice registrars (GPRs) envisage undertaking will affect workforce supply. The aim of this research was to determine practice intentions of current GPRs in a regional general practice training program (Coast City Country General Practice Training). Questionnaires were circulated to 220 GPRs undertaking general practice placements to determine characteristics of ideal practice models and intentions for future practice. Responses were received for 99 participants (45%). Current GPRs intend to work an average of less than eight half-day sessions/week, with male participants intending to work more hours (t(91) = 3.528, P = 0.001). More than one-third of this regional cohort intends to practice in metropolitan centres. Proximity to family and friends was the most important factor influencing the choice of practice location. Men ranked remuneration for work as more important (t (88) = –4.280, P \u3c 0.001) and women ranked the ability to work part-time higher (t(94) = 3.697, P \u3c 0.001). Fee-for-service payment alone, or in combination with capitation, was the preferred payment system. Only 22% of Australian medical graduates intend to own their own practice compared with 52% of international medical graduates (χ2(1) = 8.498, P = 0.004). Future general practitioners (GPs) intend to work fewer hours than current GPs. Assumptions about lifestyle factors, practice models and possible professional roles should be carefully evaluated when developing strategies to recruit GPs and GPRs into rural practice
Prevention of osteoporotic refractures in regional Australia
Objective: Clinical guidelines recommend that patients who sustain a minimal trauma fracture (MTF) should receive a bone mineral density (BMD) scan and bisphosphonate (or equivalent) therapy if diagnosed with osteoporosis. A pilot fracture liaison service (FLS) was implemented in regional NSW to improve adherence to the guidelines.
Design: Prospective cohort study with an historical control.
Setting: Primary care.
Participants: Control (n = 47) and cohort (n = 93) groups comprised patients consenting to interview who presented with a MTF to the major referral hospital 4 months before and 12 months after FLS implementation respectively.
Main outcome measures: Primary outcome measures were the rates of BMD scans and anti-osteoporotic medication initiation/review after MTF. Hospital admission data were also examined to determine death and refracture rates for all patients presenting during the study period with a primary diagnosis of MTF within 3 years of their initial fracture.
Results: Although there was no improvement in BMD scanning rates, the reported rate of medication initiation/review after fracture was significantly higher (P \u3c 0.05) in the FLS cohort. However, once adjusted for age, this association was not significant (P = 0.086). There was a lower refracture rate during the cohort period (P = 0.013), however, there were significantly more deaths (P = 0.035) within 3 years of initial fracture. When deaths were taken into account via competing risk regression, patients in the cohort period were significantly less likely to refracture than those in the control period (Hazard ratio = 0.576, P = 0.032).
Conclusions: A rurally based nurse-led FLS was associated with modest improvement after MTF. Consideration should be given to ways to strengthen the model of care to improve outcomes
Method of lines transpose: High order L-stable O(N) schemes for parabolic equations using successive convolution
We present a new solver for nonlinear parabolic problems that is L-stable and
achieves high order accuracy in space and time. The solver is built by first
constructing a single-dimensional heat equation solver that uses fast O(N)
convolution. This fundamental solver has arbitrary order of accuracy in space,
and is based on the use of the Green's function to invert a modified Helmholtz
equation. Higher orders of accuracy in time are then constructed through a
novel technique known as successive convolution (or resolvent expansions).
These resolvent expansions facilitate our proofs of stability and convergence,
and permit us to construct schemes that have provable stiff decay. The
multi-dimensional solver is built by repeated application of dimensionally
split independent fundamental solvers. Finally, we solve nonlinear parabolic
problems by using the integrating factor method, where we apply the basic
scheme to invert linear terms (that look like a heat equation), and make use of
Hermite-Birkhoff interpolants to integrate the remaining nonlinear terms. Our
solver is applied to several linear and nonlinear equations including heat,
Allen-Cahn, and the Fitzhugh-Nagumo system of equations in one and two
dimensions
- …