Super-solar metallicity at the position of the ultra-long GRB130925A

Over the last decade there has been immense progress in the follow-up of short and long GRBs, resulting in a significant rise in the detection rate of X-ray and optical afterglows, in the determination of GRB redshifts, and of the identification of the underlying host galaxies. Nevertheless, our theoretical understanding on the progenitors and central engines powering these vast explosions is lagging behind, and a newly identified class of `ultra-long' GRBs has fuelled speculation on the existence of a new channel of GRB formation. In this paper we present high signal-to-noise X-shooter observations of the host galaxy of GRB130925A, which is the fourth unambiguously identified ultra-long GRB, with prompt gamma-ray emission detected for ~20ks. The GRB line of sight was close to the host galaxy nucleus, and our spectroscopic observations cover both this region along the bulge/disk of the galaxy, in addition to a bright star-forming region within the outskirts of the galaxy. From our broad wavelength coverage we obtain accurate metallicity and dust-extinction measurements at both the galaxy nucleus, and an outer star-forming region, and measure a super-solar metallicity at both locations, placing this galaxy within the 10-20% most metal-rich GRB host galaxies. Such a high metal enrichment has implications on the progenitor models of both long and ultra-long GRBs, although the edge-on orientation of the host galaxy does not allow us to rule out a large metallicity variation along our line of sight. The spatially resolved spectroscopic data presented in this paper offer important insight into variations in the metal and dust abundance within GRB host galaxies. They also illustrate the need for IFU observations on a larger sample of GRB host galaxies at varies metallicities to provide a more quantitative view on the relation between the GRB circumburst and the galaxy-whole properties.Comment: 9 pages, 3 figures, A&A in press, matches published versio

Long optical plateau in the afterglow of the short GRB 150424A with extended emission: Evidence for energy injection by a magnetar?

Short-duration gamma-ray bursts (GRBs) with extended emission form a subclass of short GRBs, comprising about 15% of the short-duration sample. Afterglow detections of short GRBs are also rare (about 30%) because of their lower luminosity. Aims. We present a multiband data set of the short burst with extended emission, GRB 150424A, comprising of GROND observations, complemented with data from Swift/UVOT, Swift/XRT, HST, Keck/LRIS, and data points from the literature. The GRB 150424A afterglow shows an extended plateau phase, lasting about 8 h. The analysis of this unique GRB afterglow might shed light on the understanding of afterglow plateau emission, the nature of which is still under debate. Methods. We present a phenomenological analysis made by applying fireball closure relations and interpret the findings in the context of the fireball model. We discuss the plausibility of a magnetar as a central engine, which would be responsible for additional and prolonged energy injection into the fireball. Results. We find convincing evidence for energy injection into the afterglow of GRB 150424A. We find that a magnetar spin-down as the source for a prolonged energy injection requires that at least 4% of the spin-down energy is converted into radiation. © ESO, 2017.H.J.v.E. was supported by the Alexander von Humboldt foundation at the time of this work. D.A.K. acknowledges financial support from MPE, from TLS, from the Spanish research project AYA 2014-58381-P, and from Juan de la Cierva Incorporacion fellowships IJCI-2015-26153 and IJCI-2014-21669. P.S., T.W.C., J.F.G., M.T. acknowledge support through the Sofja Kovalevskaja Award from the Alexander von Humboldt Foundation of Germany. S.K. and A.N.G. acknowledge support by DFG grant K1 766/16-1. S.S. acknowledges support by the Thuringer Ministerium fur Bildung, Wissenschaft und Kultur under FKZ 12010-514. Part of the funding for GROND (both hardware as well as personnel) was generously granted from the Leibniz-Prize to G. Hasinger (DFG grant HA 1850/28-1).Peer Reviewe

Long optical plateau in the afterglow of the short GRB 150424A with extended emission

Context. Short-duration gamma-ray bursts (GRBs) with extended emission form a subclass of short GRBs, comprising about 15% of the short-duration sample. Afterglow detections of short GRBs are also rare (about 30%) because of their lower luminosity. Aims. We present a multiband data set of the short burst with extended emission, GRB 150424A, comprising of GROND observations, complemented with data from Swift/UVOT, Swift/XRT, HST, Keck/LRIS, and data points from the literature. The GRB 150424A afterglow shows an extended plateau phase, lasting about 8 h. The analysis of this unique GRB afterglow might shed light on the understanding of afterglow plateau emission, the nature of which is still under debate. Methods. We present a phenomenological analysis made by applying fireball closure relations and interpret the findings in the context of the fireball model. We discuss the plausibility of a magnetar as a central engine, which would be responsible for additional and prolonged energy injection into the fireball. Results. We find convincing evidence for energy injection into the afterglow of GRB 150424A. We find that a magnetar spin-down as the source for a prolonged energy injection requires that at least 4% of the spin-down energy is converted into radiation

Molecular Clusters in Mesoporous Materials as Precursors to Nanoparticles of a New Lacunar Ternary Compound PdxMoyP

Bimetallic clusters of composition Pd2Mo2(g5-C5H5)2(l3-CO)2(l2-CO)4 (PR3)2 (R = ethyl or phenyl) were incorporated by impregnation from solution into two different silica matrices, amorphous xerogels and ordered SBA-15, and a study of their thermal decomposition under a reducing atmosphere is reported. With both matrices, a suitable thermal treatment afforded nanoparticles of a new bimetallic phosphide. Although nanoparticles of composition PdxMoyP, isostructural with Mo3P, were formed in both matrices, they were more uniformly distributed in the SBA-15 framework and showed a narrower size distribution. The samples have been characterized by powder XRD, chemical analysis, FT-IR spectroscopy, TEM and electron tomography (3D TEM)

Large-amplitude late-time radio variability in GRB 151027B

Context. Deriving physical parameters from gamma-ray burst (GRB) afterglow observations remains a challenge, even 20 years after the discovery of afterglows. The main reason for the lack of progress is that the peak of the synchrotron emission is in the sub-mm range, thus requiring radio observations in conjunction with X-ray/optical/near-infrared data in order to measure the corresponding spectral slopes and consequently remove the ambiguity with respect to slow vs. fast cooling and the ordering of the characteristic frequencies. Aims. We have embarked on a multifrequency, multi-epoch observing campaign to obtain sufficient data for a given GRB that allows us to test the simplest version of the fireball afterglow model. Methods. We observed GRB 151027B, the 1000th Swift-detected GRB, with GROND in the optical-near-IR, ALMA in the sub-millimeter, ATCA in the radio band; we combined this with public Swift/XRT X-ray data. Results. While some observations at crucial times only return upper limits or surprising features, the fireball model is narrowly constrained by our data set, and allows us to draw a consistent picture with a fully determined parameter set. Surprisingly, we find rapid, large-amplitude flux density variations in the radio band which are extreme not only for GRBs, but generally for any radio source. We interpret them as scintillation effects, though their extreme nature requires the scattering screen to be at a much smaller distance than usually assumed, multiple screens, or a combination of the two. Conclusions. The data are consistent with the simplest fireball scenario for a blast wave moving into a constant-density medium, and slow-cooling electrons. All fireball parameters are constrained at or better than a factor of 2, except for the density and the fraction of the energy in the magnetic field which has a factor of 10 uncertainty in both directions

A TNF-Regulated Recombinatorial Macrophage Immune Receptor Implicated in Granuloma Formation in Tuberculosis

Macrophages play a central role in host defense against mycobacterial infection and anti- TNF therapy is associated with granuloma disorganization and reactivation of tuberculosis in humans. Here, we provide evidence for the presence of a T cell receptor (TCR) αβ based recombinatorial immune receptor in subpopulations of human and mouse monocytes and macrophages. In vitro, we find that the macrophage-TCRαβ induces the release of CCL2 and modulates phagocytosis. TNF blockade suppresses macrophage-TCRαβ expression. Infection of macrophages from healthy individuals with mycobacteria triggers formation of clusters that express restricted TCR Vβ repertoires. In vivo, TCRαβ bearing macrophages abundantly accumulate at the inner host-pathogen contact zone of caseous granulomas from patients with lung tuberculosis. In chimeric mouse models, deletion of the variable macrophage-TCRαβ or TNF is associated with structurally compromised granulomas of pulmonary tuberculosis even in the presence of intact T cells. These results uncover a TNF-regulated recombinatorial immune receptor in monocytes/macrophages and demonstrate its implication in granuloma formation in tuberculosis

Links between maternal postpartum depressive symptoms, maternal distress, infant gender and sensitivity in a high-risk population

<p>Abstract</p> <p>Background</p> <p>Maternal postpartum depression has an impact on mother-infant interaction. Mothers with depression display less positive affect and sensitivity in interaction with their infants compared to non-depressed mothers. Depressed women also show more signs of distress and difficulties adjusting to their role as mothers than non-depressed women. In addition, depressive mothers are reported to be affectively more negative with their sons than with daughters.</p> <p>Methods</p> <p>A non-clinical sample of 106 mother-infant dyads at psychosocial risk (poverty, alcohol or drug abuse, lack of social support, teenage mothers and maternal psychic disorder) was investigated with EPDS (maternal postpartum depressive symptoms), the CARE-Index (maternal sensitivity in a dyadic context) and PSI-SF (maternal distress). The baseline data were collected when the babies had reached 19 weeks of age.</p> <p>Results</p> <p>A hierarchical regression analysis yielded a highly significant relation between the PSI-SF subscale "parental distress" and the EPDS total score, accounting for 55% of the variance in the EPDS. The other variables did not significantly predict the severity of depressive symptoms. A two-way ANOVA with "infant gender" and "maternal postpartum depressive symptoms" showed no interaction effect on maternal sensitivity.</p> <p>Conclusions</p> <p>Depressive symptoms and maternal sensitivity were not linked. It is likely that we could not find any relation between both variables due to different measuring methods (self-reporting and observation). Maternal distress was strongly related to maternal depressive symptoms, probably due to the generally increased burden in the sample, and contributed to 55% of the variance of postpartum depressive symptoms.</p

The 2175 angstrom Extinction Feature in the Optical Afterglow Spectrum of GRB 180325A at z =. 2.25

The ultraviolet (UV) extinction feature at 2175 Å is ubiquitously observed in the Galaxy but is rarely detected at high redshifts. Here we report the spectroscopic detection of the 2175 Å bump on the sightline to the γ-ray burst (GRB) afterglow GRB 180325A at z = 2.2486, the only unambiguous detection over the past 10 years of GRB follow-up, at four different epochs with the Nordic Optical Telescope (NOT) and the Very Large Telescope (VLT)/X-shooter. Additional photometric observations of the afterglow are obtained with the Gamma-Ray burst Optical and Near-Infrared Detector (GROND). We construct the near-infrared to X-ray spectral energy distributions (SEDs) at four spectroscopic epochs. The SEDs are well described by a single power law and an extinction law with R V ≈ 4.4, A V ≈ 1.5, and the 2175 Å extinction feature. The bump strength and extinction curve are shallower than the average Galactic extinction curve. We determine a metallicity of [Zn/H] > −0.98 from the VLT/X-shooter spectrum. We detect strong neutral carbon associated with the GRB with equivalent width of W r(λ 1656) = 0.85 ± 0.05. We also detect optical emission lines from the host galaxy. Based on the Hα emission-line flux, the derived dust-corrected star formation rate is ~46 ± 4 M ⊙ yr−1 and the predicted stellar mass is log M */M ⊙ ~ 9.3 ± 0.4, suggesting that the host galaxy is among the main-sequence star-forming galaxies

Expression of interferon-γ in human adrenal gland and kidney tumours

It is known that interferon-γ (IFN-γ) is produced by activated T and NK lymphoid cells, mononuclear cells, and macrophage and dendritic cells. Our previous studies have shown that IFN-γ-like immunoreactivity also appears in human adrenal cortical tumour and phaeochromocytoma. To investigate whether human tumour cells can produce IFN-γ, we examined 429 biopsy specimens of 30 kinds of tumour and tumour-surrounding tissues in adrenal glands and in kidneys by using immunohistochemistry and in situ hybridisation. IFN-γ immunoactivity was shown in 34.3% of the adrenal cortical adenomas, 50% of the adrenal cortical carcinomas, 26.7% of the phaeochromocytomas, 26.7% of the clear cell renal cell carcinomas (RCCs), 22% of the adrenal cortexes and 40% of medullas adjacent to tumours. The positive samples and expression areas were well overlapped between the IFN-γ mRNA and the immunohistochemistry staining. Western blot analysis has further confirmed the immunohistochemistry results by showing a distinct IFN-γ band corresponding to 17.4 kDa in tissue extracts from adrenal cortical adenoma, phaeochromocytoma and clear cell RCCs. These results indicate that IFN-γ is produced by some types of tumour cells, suggesting it may play a dual role in the development of these tumours

Long optical plateau in the afterglow of the short GRB 150424A with extended emission

Context. Short-duration gamma-ray bursts (GRBs) with extended emission form a subclass of short GRBs, comprising about 15% of the short-duration sample. Afterglow detections of short GRBs are also rare (about 30%) because of their lower luminosity. Aims. We present a multiband data set of the short burst with extended emission, GRB 150424A, comprising of GROND observations, complemented with data from Swift/UVOT, Swift/XRT, HST, Keck/LRIS, and data points from the literature. The GRB 150424A afterglow shows an extended plateau phase, lasting about 8 h. The analysis of this unique GRB afterglow might shed light on the understanding of afterglow plateau emission, the nature of which is still under debate. Methods. We present a phenomenological analysis made by applying fireball closure relations and interpret the findings in the context of the fireball model. We discuss the plausibility of a magnetar as a central engine, which would be responsible for additional and prolonged energy injection into the fireball. Results. We find convincing evidence for energy injection into the afterglow of GRB 150424A. We find that a magnetar spin-down as the source for a prolonged energy injection requires that at least 4% of the spin-down energy is converted into radiation