Transcriptional Regulators.

<p>Transcriptional Regulators.</p

Genes alterations Related to Hypertrophic/Dilated Cardiomyopathy in VIP^−/− mice compared to WT mice.

<p>Genes alterations Related to Hypertrophic/Dilated Cardiomyopathy in VIP^−/− mice compared to WT mice.</p

Scatter gram of RV ED volumes measured in the short-axis MRIs of individual control mice (blue) and VIP^−/− mice (red circles) demonstrating that the RV phenotype varied in the VIP^−/− mice.

<p>Scatter gram of RV ED volumes measured in the short-axis MRIs of individual control mice (blue) and VIP^−/− mice (red circles) demonstrating that the RV phenotype varied in the VIP^−/− mice.</p

Energy Production & Regulation.

<p>Energy Production & Regulation.</p

Gene expression alterations in VIP^−/− mice compared to WT mice.

<p>Gene expression alterations in VIP^−/− mice compared to WT mice.</p

Force Generation & Propagation.

<p>Force Generation & Propagation.</p

End-diastolic multi-slice MR images acquired in the coronal plane orientation (short-axis view) through a normal mouse heart.

<p>We used slice 3, 4 and 5 for data analysis of right and left ventricle volumes. Dotted lines demonstrate as an example the areas for RV and LV volume calculation in one of the mid-ventricular slices.</p

LV and RV data for the control and VIP^−/− mice.

<p>LV and RV data for the control and VIP^−/− mice.</p

End-diastolic short-axis MR images through a control mouse heart (top panel) and a VIP^−/− mouse (bottom panel).

<p>The RV and LV endocardium has been outlined in red and black, respectively. It is clear that the VIP^−/−RV is dilated compared to the control mouse. Quantitative measures also show that the LV wall of the VIP^−/−mouse is thinner than that of the control mouse.</p

Ca²⁺ Cycling.

<p>Ca²⁺ Cycling.</p