Successful completion of pregnancy after mustard procedure for transposition of great arteries: A rare case from the developing world

Surgical repair of transposition of great arteries has undergone various evolutionary changes over the years. The initial of these treatment options was atrial septectomy followed by atrial switch and the current preferred treatment option is arterial switch operation worldwide. Due to various reasons, like lack of medical and surgical expertise atrial switch operation was commonly in practice in developing countries until few years back. Pregnancy in a patient with history of atrial switch operation poses a unique haemodynamic challenge. We report the case of a successful pregnancy in a 26 years old lady who had undergone Mustard repair surgery in the past in Pakistan

Career Development an Imperative of Job Satisfaction and Career Commitment: Empirical Evidence from Pakistani Employees in Banking Sector

The idea of strengthening human capital to beginning creativeness, business soul, and advancement through preparing the careers of institutional members using HRM policies and methods to develop different skills, mindsets and expertise with the ultimate aim to provide a range of innovative goods and services is gaining attention. The overall perspective for the research study was to discover the effects and outcomes of profession growth initiatives on companies and employees. The survey is conducted to collect data from the Banking sector in Islamabad and sample selected is of five major private banks. The data is analyzed by using SPSS and Amos to authenticate the model and propositions made by the researcher. Organizations invest resources in profession growth kinds of actions for recruiting, there tends to be less investment in similar kinds of actions for worker retention. This paper examines the link between profession preparing and profession control as antecedents of profession growth and job fulfillment, and profession dedication as its outcome. There is a significant link between the factors of profession preparing and profession control, and profession growth, and in turn, with job fulfillment and profession dedication. The paper converses about the significances of these conclusions for career development

Impact of Commodity Concentration and Geographical Concentration upon Export instability in Pakistan

This research study investigates the factors affecting export instability in Pakistan by using time-series data from 1981 to 2017. The determining factors of export instability in this study are commodity concentration index, geographical concentration index, food ratio, export earnings and total export quantity. The study employs Autoregressive Distributed Lag (ARDL) model to investigate the long-run (LR) relationship between export instability and its employed determinants. The empirical evidence reveals that commodity concentration, geographical concentration, food exports and export earnings are the key factors explaining export instability in Pakistan. The study finds the positive relationship between export instability and commodity concentration, while a negative association with geographical concentration. Furthermore, food exports and export earnings are also found to be negatively related to export instability. The study finds that concentration or depend ence on a few exports causes export instability in Pakistan, but this problem would be overcome if Pakistan’s commodity basket for exports become diversified

Phylogenetic analysis of coat protein gene of CYDV-RPV strain from Wheat

Background: Keeping in view the potential damage caused by viruses to production of different crops and possible ‘directed damages’ by manipulated viral attack in/across border collectively make phylogenetic analysis of any attacking viral specie important. Cereal yellow dwarf viruses (CYDV) are highly important viruses in wheat causing significant yield loss.Methods: Double antibody sandwich ELISA and reverse transcription polymerase chain reaction (RT-PCR) was used to detect and confirm the polerovirus i.e. CYDV-rhopalosiphum padi virus (RPV), and unassigned viruses (SGV, RMV) in Punjab and NWFP provinces. The PCR products were inserted into a pGEM®-T easy vector, which then transformed in JM-107 cells of Escherichia coli. Recombinant plasmids were sequenced. Nucleotide and predicted amino acid sequences were aligned, analyzed and compared with other RPV isolates of the family. The nucleotide sequence data were used to make a phylogenetic tree.Results: Sequencing of 600 bp of coat protein gene confirmed the presence of CYDV-RPV strain. Pakistani isolate has close phylogenetic relationship with RPV-Mexcio and RPV-Yolo (USA). They had 99.95% similarity with RPV-Pakistan. The RPV-Aus, RPV-IR, and RPV-Cal (USA) had 99.94% identities with RPV-Pakistan.Conclusion: This work led to a conclusion that there is very low genetic diversity in RPV-Pakistan. Now it is in our future interest to clarify the identity of RPV-PK with more sequencing. The current study may help scientists to formulate appropriate management strategies against CYDV-RPV

Intramedullary spinal cord lesions in children

Paediatric intramedullary spinal cord lesions are uncommon pathologies, prone to result in dismal prognosis if not managed promptly and aggressively. While children usually present in good functional grades compared to adults, early recognition and treatment is important to improve outcomes. In this review, we present tumour demographics, patient factors, and treatment modalities of intramedullary spinal cord lesions in paediatric patients

Exploring the challenges in classroom assessment: A mixed-method study of secondary schools in Pakistan

In the process of classroom assessment, data is collected regarding the skills, understanding and knowledge of students. It has very important role in enhancing academic achievement of students. Present study was designed at exploring the challenges of classroom assessment. The sample of study contained a sample of 360 participants and a concurrent mixed-method design was deployed to conduct the research. Data collection was carried out using researchers’ self-developed questionnaire. The collected data was analyzed using statistical software of SPSS version 24.0 for descriptive and inferential stats. For collection and analyses of qualitative data, classroom observation and semi-structured interviews were also conducted. The study explored those major challenges included lack of interest of both, the parents and the students; insufficient guidance on the assessment by school administration; and less or no provision of professional training in assessment to the teachers. It was recommended that the school administration should take appropriate steps for the involvement of all stakeholders. Extensive professional training should be provided to all the teachers on regular basis by the concerned departments

Translating knowledge for action against stroke--using 5-minute videos for stroke survivors and caregivers to improve post-stroke outcomes: study protocol for a randomized controlled trial (Movies4Stroke).

Background: Two thirds of the global mortality of stroke is borne by low and middle income countries (LMICs). Pakistan is the world’s sixth most populous country with a stroke-vulnerable population and is without a single dedicated chronic care center. In order to provide evidence for a viable solution responsive to this health care gap, and leveraging the existing \u3e70 % mobile phone density, we thought it rational to test the effectiveness of a mobile phone-based video intervention of short 5-minute movies to educate and support stroke survivors and their primary caregivers. Methods: Movies4Stroke will be a randomized control, outcome assessor blinded, parallel group, single center superiority trial. Participants with an acute stroke, medically stable, with mild to moderate disability and having a stable primary caregiver will be included. After obtaining informed consent the stroke survivor-caregiver dyad will be randomized. Intervention participants will have the movie program software installed in their phone, desktop, or Android device which will allow them to receive, view and repeat 5-minute videos on stroke-related topics at admission, discharge and first and third months after enrollment. The control arm will receive standard of care at an internationally accredited center with defined protocols. The primary outcome measure is medication adherence as ascertained by a locally validated Morisky Medication Adherence Scale and control of major risk factors such as blood pressure, blood sugar and blood cholesterol at 12 months post discharge. Secondary outcome measures are post-stroke complications and mortality, caregiver knowledge and change in functional outcomes after acute stroke at 1, 3, 6, 9 and 12 months. Movies4Stroke is designed to enroll 300 participant dyads after inflating 10 % to incorporate attrition and noncompliance and has been powered at 95 % to detect a 15 % difference between intervention and usual care arm. Analysis will be done by the intention-to-treat principle. Discussion: Movies4Stroke is a randomized trial testing an application aimed at supporting caregivers and stroke survivors in a LMIC with no rehabilitation or chronic support systems