Effects of ceftiofur sodium liposomes on free radical formation in mice

To examine the effects of ceftiofur sodium liposomes on the free radical formation in liver of mice, 24 mice were assigned randomly into three groups, i.e., 1) ceftiofur sodium; 2) ceftiofur sodium liposomes and 3) physiological saline. Treatments were applied via intraperitoneal injections for 7 days. At the end of the treatment period, animals were euthanized and liver collected for analysis of superoxide dismutase (SOD) activity and malondialdehyde (MDA) contents and the ability of liver tissue to suppress hydroxyl radical formation. Ceftiofur sodium liposomes-treated mice had higher activity of SOD than ceftiofur sodium- and saline-treated mice; however, MDA content and the ability of liver tissue to suppress hydroxyl radical formation did not reach statistical significance among groups. It was concluded that ceftiofur sodium liposomes can improve the SOD activity compared to ceftiofur alone in mice

Search for anomalous production of prompt like-sign lepton pairs at root s=7 TeV with the ATLAS detector

An inclusive search for anomalous production of two prompt, isolated leptons with the same electric charge is presented. The search is performed in a data sample corresponding to 4.7 fb-1 of integrated luminosity collected in 2011 at √s =7 TeV with the ATLAS detector at the LHC. Pairs of leptons (e± e±, e± μ ±, and μ ± μ ±) with large transverse momentum are selected, and the dilepton invariant mass distribution is examined for any deviation from the Standard Model expectation. No excess is found, and upper limits on the production cross section of like-sign lepton pairs from physics processes beyond the Standard Model are placed as a function of the dilepton invariant mass within a fiducial region close to the experimental selection criteria. The 95% confidence level upper limits on the cross section of anomalous e± e ±, e± μ ±, or μ ± μ ± production range between 1.7 fb and 64 fb depending on the dilepton mass and flavour combination. © 2012 Cern for the benefit of the ATLAS collaboration