1,000 research outputs found
Water waves overtopping over barriers
A numerical and experimental analysis of the wave overtopping over emerged and submerged structures, is presented. An original model is used in order to simulate three-dimensional free surface flows. The model is based on the numerical solution of the motion equations expressed in an integral form in time-dependent curvilinear coordinates. A non-intrusive and continuous-in-space image analysis technique, which is able to properly identify the free surface even in very shallow waters or breaking waves, is adopted for the experimental tests. Numerical and experimental results are compared, for several wave and water depth conditions
Structural Simulation of Transcatheter Heart Valve in Transcatheter Heart Valve
The durability of transcatheter heart valves (TAV) remains the main disadvantage of transcatheter heart valve implantation (TAVI) for treating aortic valve stenosis. In this study, we assessed the structural mechanics of TAV-in-TAVI using patient-specific modeling. A parametric analysis highlighted that the outcome of TAV-in-TAV depends on the implanted device position and the planned device to be implanted. Contact pressure evinced the impact of different implantation depth and device size on the TAV-in-TAV. This study may bring new insight in the biomechanical performance of TAV to evaluate options for future interventions when the current TAVs experience device failure
Spectral singularities for Non-Hermitian one-dimensional Hamiltonians: puzzles with resolution of identity
We examine the completeness of bi-orthogonal sets of eigenfunctions for
non-Hermitian Hamiltonians possessing a spectral singularity. The correct
resolutions of identity are constructed for delta like and smooth potentials.
Their form and the contribution of a spectral singularity depend on the class
of functions employed for physical states. With this specification there is no
obstruction to completeness originating from a spectral singularity.Comment: 25 pages, more refs adde
Parametric analysis of transcatheter aortic valve replacement in transcatheter aortic valve replacement: evaluation of coronary flow obstruction
Transcatheter aortic valve replacement (TAVR) is increasingly being considered for use in younger patients having longer life expectancy than those who were initially treated. The TAVR-in-TAVR procedure represents an appealing strategy to treat failed transcatheter heart valves (THV) likely occurring in young patients. However, the permanent displacement of first THV can potentially compromise the coronary access and ultimately inhibit the blood flow circulation. The objective of this study was to use finite-element analysis (FEA) to quantify coronary flow in a patient who underwent TAVR-in-TAVR. A parametric investigation was carried out to determine the impact of both the implantation depth and device size on coronary flow for several deployment configurations. The FEAs consisted of first delivering the SAPIEN 3 Ultra THV and then positioning the Evolut PRO device. Findings indicates that high implantation depth and device undersize of the second THV could significantly reduce coronary flow to 20% of its estimated level before TAVR. Additionally, a positive correlation was observed between coronary flow and the valve-to-coronary distance (R = 0.86 and p = 0.032 for the left coronary artery, and R = 0.93 and p = 0.014 for the right coronary artery). This study demonstrated that computational modeling can provide valuable insights to improve the pre-procedural planning of TAVR-in-TAVR
Biomechanical performance of the Bicaval Transcatheter System for the treatment of severe tricuspid regurgitation
Introduction: Tricuspid regurgitation (TR) is a relatively common valvular disease, which can result from structural abnormalities of any anatomic part of the tricuspid valve. Severe TR is linked to congestive heart failure and hemodynamic impairment, resulting in high mortality when repaired by elective surgery. This study was undertaken to quantify the structural and hemodynamic performance of the novel Transcatheter Bicaval Valves System (TricValve) percutaneously implanted in the superior vena cava (SVC) and inferior vena cava (IVC) of two patients with severe TR and venous congestion. Methods: After developing the SVC and IVC device models, the contact pressure exerted on the vena cava wall was obtained by computational analysis. Both smoothed-particle hydrodynamics (SPH) and computational fluid dynamics were carried out to quantify caval reflux in the right atrium and the pressure field of pre- and post-TricValve scenarios, respectively. Results: Analysis of contact pressure highlighted the main anchoring area of the SVC device occurring near the SVC device belly, while the IVC device exerted pronounced forces in the device’s proximal and distal parts. SPH-related flow velocities revealed the absence of caval reflux, and a decrease in time-averaged pressure was observed near the SVC and IVC after TricValve implantation. Discussion: Findings demonstrated the potential of computational tools for enhancing our understanding of the biomechanical performance of structural tricuspid valve interventions and improving the way we design next-generation transcatheter therapies to treat the tricuspid valve with heterotopic caval valve implantation
Complex Lagrangians and phantom cosmology
Motivated by the generalization of quantum theory for the case of
non-Hermitian Hamiltonians with PT symmetry, we show how a classical
cosmological model describes a smooth transition from ordinary dark energy to
the phantom one. The model is based on a classical complex Lagrangian of a
scalar field. Specific symmetry properties analogous to PT in non-Hermitian
quantum mechanics lead to purely real equation of motion.Comment: 11 pages, to be published in J.Phys.A, refs. adde
Equidistance of the Complex 2-Dim Anharmonic Oscillator Spectrum: Exact Solution
We study a class of quantum two-dimensional models with complex potentials of
specific form. They can be considered as the generalization of a recently
studied model with quadratic interaction not amenable to conventional
separation of variables. In the present case, the property of shape invariance
provides the equidistant form of the spectrum and the algorithm to construct
eigenfunctions analytically. It is shown that the Hamiltonian is
non-diagonalizable, and the resolution of identity must include also the
corresponding associated functions. In the specific case of anharmonic
second-plus-fourth order interaction, expressions for the wave functions and
associated functions are constructed explicitly for the lowest levels, and the
recursive algorithm to produce higher level wave functions is given.Comment: 17 p.
How a complex basaltic volcanic system works: Constraints from integrating seismic, geodetic, and petrological data at Mount Etna volcano during the July-August 2014 eruption
Integrating geodetic, seismic, and petrological data for a recent eruptive episode at Mount Etna has enabled us to define the history of magma storage and transfer within the multilevel structure of the volcano, providing spatial and temporal constraints for magma movements before the eruption. Geodetic data related to the July-August 2014 activity provide evidence of a magma reservoir at similar to 4kmbelow sea level. This reservoir pressurized from late March 2014 and fed magmas that were then erupted from vents on the lower eastern flank of North-East Crater (NEC) and at New South-East Crater (NSEC) summit crater during the July eruptive activity. Magma drainage caused its depressurization since mid-July. Textural and microanalytical data obtained from plagioclase crystals indicate similar disequilibrium textures and compositions at the cores in lavas erupted at the base of NEC and NSEC, suggesting comparable deep histories of evolution and ascent. Conversely, the compositional differences observed at the crystal rims have been associated to distinct degassing styles during storage in a shallow magma reservoir. Seismic data have constrained depth for a shallow part of the plumbing system at 1-2kmabove sea level. Timescales of magma storage and transfer have also been calculated through diffusion modeling of zoning in olivine crystals of the two systems. Our data reveal a common deep history of magmas from the two systems, which is consistent with a recharging phase by more mafic magma between late March and early June 2014. Later, the magma continued its crystallization under distinct chemical and physical conditions at shallower levels
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