979 research outputs found
The impact of natural disasters on crime
This study addresses the following questions in the context of a developing coun- try. Do crimes increase following natural disasters? Does an upcoming election or the presence of a strong local media, which potentially increases the incentive of the gov- ernment to provide disaster relief, mitigate the eect of disasters on crime rates? I nd that crime rates tend to increase following moderate to big disasters. Furthermore, a higher pre-disaster growth of newspapers has a mitigating eect on the crime response to disasters. Elections also in uence the crime response to disasters. Crimes are more likely to rise following disasters in the years that are close to an election year.crime rate; natural disaster; role of media and elections; developing country
Hydrophobic hydration driven self-assembly of Curcumin in water: Similarities to nucleation and growth under large metastability, and an analysis of water dynamics at heterogeneous surfaces
As the beneficial effects of curcumin have often been reported to be limited
to its small concentrations, we have undertaken a study to find the aggregation
properties of curcumin in water by varying the number of monomers. Our
molecular dynamics simulation results show that the equilibrated structure is
always an aggregated state with remarkable structural rearrangements as we vary
the number of curcumin monomers from 4 to 16 monomers. We find that curcumin
monomers form clusters in a very definite pattern where they tend to aggregate
both in parallel and anti-parallel orientation of the phenyl rings, often seen
in the formation of beta-sheet in proteins. A considerable enhancement in the
population of parallel alignments is observed with increasing the system size
from 12 to 16 curcumin monomers. Due to the prevalence of such parallel
alignment for large system size, a more closely packed cluster is formed with
maximum number of hydrophobic contacts. We also follow the pathway of cluster
growth, in particular the transition from the initial segregated to the final
aggregated state. We find the existence of a metastable structural intermediate
involving a number of intermediate-sized clusters dispersed in the solution.
The course of aggregation bears similarity to nucleation and growth in highly
metastable state. The final aggregated form remains stable with total exclusion
of water from its sequestered hydrophobic core. We also investigate water
structure near the cluster surface along with their orientation. We find that
water molecules form a distorted tetrahedral geometry in the 1st solvation
layer of the cluster, interacting strongly with hydrophilic groups at the
surface of curcumin. The dynamics of such quasi-bound water molecules near the
surface of curcumin cluster is considerably slower than the bulk signifying a
restricted motion as often found in protein hydration layer.Comment: 31 pages, 9 figure
Sensitivity of Water Dynamics to Biologically Significant Surfaces of Monomeric Insulin: Role of Topology and Electrostatic Interactions
In addition to the biologically active monomer of the protein Insulin
circulating in human blood, the molecule also exists in dimeric and hexameric
forms that are used as storage. The Insulin monomer contains two distinct
surfaces, namely the dimer forming surface (DFS) and the hexamer forming
surface (HFS) that are specifically designed to facilitate the formation of the
dimer and the hexamer, respectively. In order to characterize the structural
and dynamical behaviour of interfacial water molecules near these two surfaces
(DFS and HFS), we performed atomistic molecular dynamics simulations of Insulin
with explicit water. Dynamical characterization reveals that the structural
relaxation of the hydrogen bonds formed between the residues of DFS and the
interfacial water molecules is faster than those formed between water and that
of the HFS. Furthermore, the residence times of water molecules in the protein
hydration layer for both the DFS and HFS are found to be significantly higher
than those for some of the other proteins studied so far, such as HP-36 and
lysozyme. The surface topography and the arrangement of amino acid residues
work together to organize the water molecules in the hydration layer in order
to provide them with a preferred orientation. HFS having a large polar solvent
accessible surface area and a convex extensive nonpolar region, drives the
surrounding water molecules to acquire predominantly a clathrate-like
structure. In contrast, near the DFS, the surrounding water molecules acquire
an inverted orientation owing to the flat curvature of hydrophobic surface and
interrupted hydrophilic residual alignment. We have followed escape trajectory
of several such quasi-bound water molecules from both the surfaces and
constructed free energy surfaces of these water molecules.These free energy
surfaces reveal the differences between the two hydration layers.Comment: 34 pages, 10 figure
Environmental regulation and development : a cross-country empirical analysis
The authors develop comparative indices of environmental policy and performance for 31 countries using a quantified analysis of reports prepared for the United Nations Conference on Environmental and Development. In cross-country regressions, they find a very strong, continuous association between their indicators and national income per capita, particularly when adjusted for purchasing power parity. Their results suggest a characteristic progression in development. Poor agrarian economies focus first on natural resource protection. With increased urbanization and industrialization, countries move from initial regulation of water pollution to air pollution control. The authors highlight the importance of institutional development. Environmental regulation is more advanced in developing countries with relatively secure property rights, effective legal and judicial systems, and efficient public administration.Public Health Promotion,Environmental Economics&Policies,Health Economics&Finance,Agricultural Research,Economic Theory&Research,Environmental Economics&Policies,Health Economics&Finance,Agricultural Research,Economic Theory&Research,Environmental Governance
Productivity Puzzling: A Study on Recent Behaviour of UK and Bangladesh
Productivity is a multi-faceted concept; no single definition can holistically describe it. However, in the simplest form, productivity signifies the ratio between the input and output. In achieving sustained economic growth of a country, increased productivity remains as the key component. Productivity signifies a continual striving towards the economically most efficient mode of production of goods, commodities, and services needed by a society. Prior to the mid-1980s, labour productivity growth was a useful barometer of the world economy: it was low when the economy was depressed and high when it was booming. In many larger advanced economies like UK labour productivity growth slowed sharply and remained subdued for years after the credit crisis of 2007/08. After the early 1980s productivity issues were considered as a priority area for action in Bangladesh: a small economic country, but Productivity has slowed down again significantly during the last decade (2001-2012) because of some reasons. In this paper, we tried to find out the reasons behind for productivity puzzling in UK as well as in Bangladesh. For UK productivity puzzle, this study considered that workforce composition, lower business investment, flexibility of labour market, Impaired resource allocation, and public sector productivity were the major factors that might have caused productivity to fall and in Bangladesh, insignificant role of allocative efficiency of resources within industry, poor performing public sector, inadequate public sector investment, labor union, firm size and productivity are inversely related were the major factors that might had caused low productivity. In light of these findings, it is found that there is a similarity between productivity puzzling factor of UK and Bangladesh. Performance and investment in public sector and improper resource allocation are common productivity puzzling factor for both the countries. Keywords: Productivity Puzzling, UK, Banglades
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