661 research outputs found
THE PRACTICALITY AND EFFECTIVENESS OF LESSON PLAN SET ON NATURAL SCIENCE SUBJECT IN TRAINING THE CRITICAL THINKING SKILLS OF JUNIOR HIGH SCHOOL STUDENTS
This research aims to evaluate the practicality and effectiveness of natural science subject lesson plan set on the concept of plant structure and its utilization in technology in training the critical thinking skills of junior high school students. The lesson plan set includes syllabi, lesson plan, student worksheet, teaching material, media, and assessment sheet. The development is using Plomp and Nieveen’s development steps which consist of preliminary research and prototyping. The method used in this research is descriptive qualitative. The research is done in five months (July-November 2017) at the State Junior High Schools 1 in Banjarmasin. The subject of the small group test is 12 students of VIII B Class and field test is 34 students of VIII D Class. The subject appointment is done purposively, which based on high, medium, and low academic capability. The practicality data is obtained from 1) lesson plan implementation and 2) students’ responses. The effectiveness data is obtained from the learning result of 1) spiritual, 2) affective, 3) cognitive, 4) psychomotor, 5) critical thinking skills, 6) teachers’ activities, and 7) students’ activities. Data analysis is done descriptively. The result shows that the lesson plan set is practical to use based on the implementation of lesson plan and students’ responses. Lesson plan set is effective to use based on the criteria of the learning result of 1) spiritual, 2) affective, 3) cognitive, 4) psychomotor, 5) critical thinking skills, 6) teachers’ activities, and 7) students’ activities. Article visualizations
On the background in the reaction and mixed event simulation
In this paper we evaluate sources of background for the , with the detected through its decay channel, to
compare with the experiment carried out at ELSA. We find background from
followed by decay of a into two ,
recombining one and one , and from the reaction with subsequent decay of the into two photons. This
background accounts for the data at invariant masses beyond 700
MeV, but strength is missing at lower invariant masses which was attributed to
photon misidentification events, which we simulate to get a good reproduction
of the experimental background. Once this is done, we perform an event mixing
simulation to reproduce the calculated background and we find that the method
provides a good description of the background at low invariant
masses but fakes the background at high invariant masses, making background
events at low invariant masses, which are due to misidentification
events, responsible for the background at high invariant masses which is due to
the and reactions.Comment: 10 pages, 5 figure
A spectroscopic and molecular dynamics study on the aggregation process of a long-acting lipidated therapeutic peptide: the case of semaglutide
The aggregation properties of semaglutide, a lipidated peptide drug agonist of the Glucagon-like peptide 1 receptor recently approved for the treatment of type 2 diabetes, have been investigated by spectroscopic techniques (UV-Vis absorption, steady-state and time-resolved fluorescence, and electronic circular dichroism) and molecular dynamics simulations. We show that in the micromolar concentration region, in aqueous solution, semaglutide is present as monomeric and dimeric species, with a characteristic monomer-to-dimer transition occurring at around 20 μM. The lipid chain stabilizes a globular morphology of the monomer and dimer species, giving rise to a locally well-defined polar outer surface where the lipid and peptide portions are packed to each other. At very long times, these peptide clusters nucleate the growth of larger aggregates characterized by blue luminescence and a β-sheet arrangement of the peptide chains. The understanding of the oligomerization and aggregation potential of peptide candidates is key for the development of long acting and stable drugs
A new highly segmented start counter for the CLAS detector
The design, construction and performance of a highly segmented Start Counter are described. The Start Counter is an integral part of the trigger used in photon beam running with CLAS in Hall B at the Thomas Jefferson National Accelerator Facility (TJNAF). The Start Counter is constructed of 24 2.2-mm-thick single-ended scintillation paddles, forming a hermetic hexagon around the target region. This device measures the interaction time of the incoming photon in the target by detecting the outgoing particles. The counter provides complex trigger topologies, shows good efficiency and achieved a time resolution of 350 ps
Dark matter search in a Beam-Dump eXperiment (BDX) at Jefferson Lab
MeV-GeV dark matter (DM) is theoretically well motivated but remarkably
unexplored. This Letter of Intent presents the MeV-GeV DM discovery potential
for a 1 m segmented plastic scintillator detector placed downstream of the
beam-dump at one of the high intensity JLab experimental Halls, receiving up to
10 electrons-on-target (EOT) in a one-year period. This experiment
(Beam-Dump eXperiment or BDX) is sensitive to DM-nucleon elastic scattering at
the level of a thousand counts per year, with very low threshold recoil
energies (1 MeV), and limited only by reducible cosmogenic backgrounds.
Sensitivity to DM-electron elastic scattering and/or inelastic DM would be
below 10 counts per year after requiring all electromagnetic showers in the
detector to exceed a few-hundred MeV, which dramatically reduces or altogether
eliminates all backgrounds. Detailed Monte Carlo simulations are in progress to
finalize the detector design and experimental set up. An existing 0.036 m
prototype based on the same technology will be used to validate simulations
with background rate estimates, driving the necessary RD towards an
optimized detector. The final detector design and experimental set up will be
presented in a full proposal to be submitted to the next JLab PAC. A fully
realized experiment would be sensitive to large regions of DM parameter space,
exceeding the discovery potential of existing and planned experiments by two
orders of magnitude in the MeV-GeV DM mass range.Comment: 28 pages, 17 figures, submitted to JLab PAC 4
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