Eight-Dimensional Mid-Infrared/Optical Bayesian Quasar Selection

We explore the multidimensional, multiwavelength selection of quasars from mid-IR (MIR) plus optical data, specifically from Spitzer-IRAC and the Sloan Digital Sky Survey (SDSS). We apply modern statistical techniques to combined Spitzer MIR and SDSS optical data, allowing up to 8-D color selection of quasars. Using a Bayesian selection method, we catalog 5546 quasar candidates to an 8.0 um depth of 56 uJy over an area of ~24 sq. deg; ~70% of these candidates are not identified by applying the same Bayesian algorithm to 4-color SDSS optical data alone. Our selection recovers 97.7% of known type 1 quasars in this area and greatly improves the effectiveness of identifying 3.5<z<5 quasars. Even using only the two shortest wavelength IRAC bandpasses, it is possible to use our Bayesian techniques to select quasars with 97% completeness and as little as 10% contamination. This sample has a photometric redshift accuracy of 93.6% (Delta Z +/-0.3), remaining roughly constant when the two reddest MIR bands are excluded. While our methods are designed to find type 1 (unobscured) quasars, as many as 1200 of the objects are type 2 (obscured) quasar candidates. Coupling deep optical imaging data with deep mid-IR data could enable selection of quasars in significant numbers past the peak of the quasar luminosity function (QLF) to at least z~4. Such a sample would constrain the shape of the QLF and enable quasar clustering studies over the largest range of redshift and luminosity to date, yielding significant gains in our understanding of quasars and the evolution of galaxies.Comment: 49 pages, 14 figures, 7 tables. AJ, accepte

An Extremely Deep Wide-Field Near-Infrared Survey: Bright Galaxy Counts and Local Large Scale Structure

We present a deep, wide-field near-infrared (NIR) survey over five widely separated fields at high Galactic latitude covering a total of ~ 3 deg^2 in J, H, and Ks. The deepest areas of the data (~ 0.25 deg^2) extend to a 5 sigma limiting magnitude of JHKs > 24 in the AB magnitude system. Although depth and area vary from field to field, the overall depth and large area of this dataset make it one of the deepest wide-field NIR imaging surveys to date. This paper discusses the observations, data reduction, and bright galaxy counts in these fields. We compare the slope of the bright galaxy counts with the Two Micron All Sky Survey (2MASS) and other counts from the literature and explore the relationship between slope and supergalactic latitude. The slope near the supergalactic equator is sub- Euclidean on average pointing to the possibility of a decreasing average space density of galaxies by ~ 10-15% over scales of ~ 250-350 Mpc. On the contrary, the slope at high supergalactic latitudes is strongly super-Euclidean on average suggesting an increase in the space density of galaxies as one moves from the voids just above and below the supergalactic plane out to distances of ~ 250-350 Mpc. These results suggest that local large scale structure could be responsible for large discrepancies in the measured slope between different studies in the past. In addition, the local universe away from the supergalactic plane appears to be underdense by ~ 25-100% relative to the space densities of a few hundred megaparsecs distant. Subject headings: cosmology: observations and large scale structure of universe-galaxies: fundamental parameters (counts)-infrared: galaxiesComment: Accepted to ApJS, 18 Pages, 14 Figures, 8 Table

Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis

Introduction Psoriatic arthritis (PsA) affects around 150 000 people in the UK of whom around 50% require treatment with biologics. The most used biologics for PsA target tumour necrosis factor (TNF) or interleukin-17A (IL-17A). About 50% of patients respond to each, but it is not currently possible to predict response for individual patients, necessitating sequential treatment steps. A recent proof of concept study in PsA suggested that using peripheral immunophenotype to choose therapy could improve time to treatment response. This study will test the hypothesis, within an open-label parallel-group biomarker-stratified multicentre randomised controlled trial, which the baseline proportion of CD4+T cells with an activated type 17 immunophenotype (Th17 levels) predicts response to IL-17A or TNF inhibitors in PsA. Additional analyses will identify if the model can be refined by combining additional clinical and immunophenotypic factors. Statistical modelling will be used to predict the likely effectiveness of these approaches compared with standard care. Methods and analysis Patients with PsA eligible to start their first biologic as part of standard care are recruited and baseline blood tests are taken for immunophenotyping. Participants are stratified equally by Th17 levels and randomised 1:1 to receive either TNF (adalimumab) or IL-17A (secukinumab) inhibitors. The primary analysis will establish the interaction between baseline immunophenotype and treatment on the primary outcome (achievement of minimal disease activity criteria at week 24). In secondary analysis, modelling will identify if this prediction model can be optimised further by incorporating clinical phenotypes and additional immunophenotyping techniques. Ethics and dissemination Ethical approval for the study was granted by the North West Preston Research Ethics Committee (ref 21/NW/0016). Dissemination will be via conference presentations and peer-reviewed publications, aiming to impact on treatment guidelines. Trial registration number ISRCTN17228602

Measuring the Sources of the Intergalactic Ionizing Flux

We use a wide-field (0.9 square degree) X-ray sample with optical and GALEX ultraviolet observations to measure the contribution of Active Galactic Nuclei (AGNs) to the ionizing flux as a function of redshift. Our analysis shows that the AGN contribution to the metagalactic ionizing background peaks around z=2. The measured values of the ionizing background from the AGNs are lower than previous estimates and confirm that ionization from AGNs is insufficient to maintain the observed ionization of the intergalactic medium (IGM) at z>3. We show that only sources with broad lines in their optical spectra have detectable ionizing flux and that the ionizing flux seen in an AGN is not correlated with its X-ray color. We also use the GALEX observations of the GOODS-N region to place a 2-sigma upper limit of 0.008 on the average ionization fraction fnu(700 A)/fnu(1500 A) for 626 UV selected galaxies in the redshift range z=0.9-1.4. We then use this limit to estimate an upper bound to the galaxy contribution in the redshift range z=0-5. If the z~1.15 ionization fraction is appropriate for higher redshift galaxies, then contributions from the galaxy population are also too low to account for the IGM ionization at the highest redshifts (z>4).Comment: 15 pages, Accepted by The Astrophysical Journa

First Measurement of the Clustering Evolution of Photometrically-Classified Quasars

We present new measurements of the quasar autocorrelation from a sample of \~80,000 photometrically-classified quasars taken from SDSS DR1. We find a best-fit model of $\omega(\theta) = (0.066\pm^{0.026}_{0.024})\theta^{-(0.98\pm0.15)}$ for the angular autocorrelation, consistent with estimates from spectroscopic quasar surveys. We show that only models with little or no evolution in the clustering of quasars in comoving coordinates since z~1.4 can recover a scale-length consistent with local galaxies and Active Galactic Nuclei (AGNs). A model with little evolution of quasar clustering in comoving coordinates is best explained in the current cosmological paradigm by rapid evolution in quasar bias. We show that quasar biasing must have changed from b_Q~3 at a (photometric) redshift of z=2.2 to b_Q~1.2-1.3 by z=0.75. Such a rapid increase with redshift in biasing implies that quasars at z~2 cannot be the progenitors of modern L* objects, rather they must now reside in dense environments, such as clusters. Similarly, the duration of the UVX quasar phase must be short enough to explain why local UVX quasars reside in essentially unbiased structures. Our estimates of b_Q are in good agreement with recent spectroscopic results, which demonstrate the implied evolution in b_Q is consistent with quasars inhabiting halos of similar mass at every redshift. Treating quasar clustering as a function of both redshift and luminosity, we find no evidence for luminosity dependence in quasar clustering, and that redshift evolution thus affects quasar clustering more than changes in quasars' luminosity. We provide a new method for quantifying stellar contamination in photometrically-classified quasar catalogs via the correlation function.Comment: 34 pages, 10 figures, 1 table, Accepted to ApJ after: (i) Minor textual changes; (ii) extra points added to Fig.

Ultradeep Ks Imaging in the GOODS-N

We present an ultradeep Ks-band image that covers 0.5*0.5 deg^2 centered on the Great Observatories Origins Deep Survey-North (GOODS-N). The image reaches a 5 \sigma depth of Ks(AB) = 24.45 in the GOODS-N region, which is as deep as the GOODS-N Spitzer Infrared Array Camera (IRAC) 3.6 \mu m image. We present a new method of constructing IRAC catalogs that uses the higher spatial resolution Ks image and catalog as priors and iteratively subtracts fluxes from the IRAC images to estimate the IRAC fluxes. Our iterative method is different from the \chi^2 approach adopted by other groups. We verified our results using data taken in two different epochs of observations, as well as by comparing our colors with the colors of stars and with the colors derived from model spectral energy distributions (SEDs) of galaxies at various redshifts. We make available to the community our WIRCam Ks-band image and catalog (94951 objects in 0.25 deg^2), the Interactive Data Language (IDL) pipeline used for reducing the WIRCam images, and our IRAC 3.6 to 8.0 \mu m catalog (16950 objects in 0.06 deg^2 at 3.6 \mu m). With this improved Ks and IRAC catalog and a large spectroscopic sample from our previous work, we study the color-magnitude and color-color diagrams of galaxies. We compare the effectiveness of using Ks and IRAC colors to select active galactic nuclei (AGNs) and galaxies at various redshifts. We also study a color selection of z = 0.65--1.2 galaxies using the Ks, 3.6 \mu m, and 4.5 \mu m bands.Comment: Accepted for publication on ApJS. Online data are availabl

Questioning Classic Patient Classification Techniques in Gait Rehabilitation: Insights from Wearable Haptic Technology

Classifying stroke survivors based on their walking abilities is an important part of the gait rehabilitation process. It can act as powerful indicator of function and prognosis in both the early days after a stroke and long after a survivor receives rehabilitation. This classification often relies solely on walking speed; a quick and easy measure, with only a stopwatch needed. However, walking speed may not be the most accurate way of judging individual’s walking ability. Advances in technology mean we are now in a position where ubiquitous and wearable technologies can be used to elicit much richer measures to characterise gait. In this paper we present a case study from one of our studies, where within a homogenous group of stroke survivors (based on walking speed classification) important differences in individual results and the way they responded to rhythmic haptic cueing were identified during the piloting of a novel gait rehabilitation technique

How does the radio enhancement of broad absorption line quasars relate to colour and accretion rate?

The origin of radio emission in different populations of radio-quiet quasars is relatively unknown, but recent work has uncovered various drivers of increased radio-detection fraction. In this work, we pull together three known factors: optical colour (g - i), C IV distance (a proxy for L/LEdd), and whether or not the quasar contains broad absorption lines (BALQSOs) which signify an outflow. We use SDSS (Sloan Digital Sky Survey) DR14 spectra along with the LOFAR Two Metre Sky Survey Data Release 2 and find that each of these properties have an independent effect. BALQSOs are marginally more likely to be radio-detected than non-BALQSOs at similar colours and L/LEdd, moderate reddening significantly increases the radio-detection fraction and the radio detection increases with L/LEdd above a threshold for all populations. We test a widely used simple model for radio wind shock emission and calculate energetic efficiencies that would be required to reproduce the observed radio properties. We discuss interpretations of these results concerning radio-quiet quasars more generally. We suggest that radio emission in BALQSOs is connected to a different physical origin than the general quasar population since they show different radio properties independent of colour and C IV distance

The HELLAS2XMM Survey. XII. The infrared/sub-millimeter view of an X-ray selected Type 2 quasar at z=2

We present multi-wavelength observations (from optical to sub-millimeter, including Spitzer and SCUBA) of H2XMMJ 003357.2-120038 (also GD158_19), an X-ray selected, luminous narrow-line (Type 2) quasar at z=1.957 selected from the HELLAS2XMM survey. Its broad-band properties can be reasonably well modeled assuming three components: a stellar component to account for the optical and near-IR emission, an AGN component (i.e., dust heated by an accreting active nucleus), dominant in the mid-IR, with an optical depth at 9.7 micron along the line of sight (close to the equatorial plane of the obscuring matter) of tau(9.7)=1 and a full covering angle of the reprocessing matter (torus) of 140 degrees, and a far-IR starburst component (i.e., dust heated by star formation) to reproduce the wide bump observed longward of 70 micron. The derived star-formation rate is about 1500 solar masses per year. The overall modeling indicates that GD158_19 is a high-redshift X-ray luminous, obscured quasar with coeval powerful AGN activity and intense star formation. It is probably caught before the process of expelling the obscuring gas has started, thus quenching the star formation.Comment: 7 pages, 3 figures, 1 table, accepted for publication by MNRA

Detections of CO Molecular Gas in 24um-Bright ULIRGs at z~2 in the Spitzer First Look Survey

We present CO observations of 9 ULIRGs at z~2 with S(24\mu m)>1mJy, previously confirmed with the mid-IR spectra in the Spitzer First Look Survey. All targets are required to have accurate redshifts from Keck/GEMINI near-IR spectra. Using the Plateau de Bure millimeter-wave Interferometer (PdBI) at IRAM, we detect CO J(3-2) [7 objects] or J(2-1) [1 object] line emission from 8 sources with integrated intensities Ic ~(5-9)sigma. The CO detected sources have a variety of mid-IR spectra, including strong PAH, deep silicate absorption and power-law continuum, implying that these molecular gas rich objects at z~2 could be either starbursts or dust obscured AGNs. The measured line luminosity L'[CO] is (1.28-3.77)e+10[K km/s pc^2]. The averaged molecular gas mass M(H2) is 1.7e+10Msun, assuming CO-to-H2 conversion factor of 0.8Msun/[K km/s pc^2]. Three sources (33%) -- MIPS506, MIPS16144 & MIPS8342 -- have double peak velocity profiles. The CO double peaks in MIPS506 and MIPS16144 show spatial separations of 45kpc and 10.9kpc, allowing the estimates of the dynamical masses of 3.2e+11*sin^(-2)(i)Msun and 5.4e+11*sin^{-2}(i)Msun respectively. The implied gas fraction, M(gas)/M(dyn), is 3% and 4%, assuming an average inclination angle. Finally, the analysis of the HST/NIC2 images, mid-IR spectra and IR SED revealed that most of our sources are mergers, containing dust obscured AGNs dominating the luminosities at (3-6)um. Together, these results provide some evidence suggesting SMGs, bright 24um z~2 ULIRGs and QSOs could represent three different stages of a single evolutionary sequence, however, a complete physical model would require much more data, especially high spatial resolution spectroscopy.Comment: 15 pages, 8 figures, accepted for publication in ApJ