Assessment of serum L-fucose in brain tumor cases

<b>Background:</b> Glycosylation of altered tumor cell in relation to cellular heterogeneity in human intracranial tumors remains relatively unexposed. Serum protein-bound carbohydrate, L-Fucose is reported to be overexpressed during tumor progression by many investigators. Therefore, there is a need to determine the diagnostic, prognostic, functional significance of glycoprotein elevations in various cases of tumors. <b> Objective:</b> The objective of the present study was to evaluate the clinical utility of serum L-fucose in patients with brain tumor. <b> Materials and Methods:</b> Serum glyco-conjugate levels were estimated in 99 patients with brain tumors. Estimation of L-fucose was carried out colorimetrically by the method of Winzler using cysteine hydrochloride. <b> Results:</b> There was a significant increase in L-fucose level in most of the patients. In the posttreatment cases, the L-fucose levels were apparently low compared to preoperative values. <b> Conclusion:</b> Our results showed that the rise in serum L-fucose may be used as a general marker for brain tumors in addition to other markers

From cages to wedges and clefts : Design of some novel hosts based on Image , Image , Image -triquinane framework

Annulation of aromatic rings on the folded Image ,Image ,Image -triquinane backbone has led to the design of potential host systems Image and Image whose crystal structures have been determined

Response of Reverse Flotation on Iron Ore Slimes Varying in Size Distribution and Assay Content

In view of the depletion of high grade iron ores, steel producers have adopted various beneficiating techniques to utilize the medium and low grade iron ores. M/s JSW too has adopted the beneficiation of ores to make use of medium and low grade iron ore. The efficiency of most commonly used technology for beneficiation of iron ores such as spiral concentration and magnetic separation become inefficient with the content of higher amount of ultra fines. Iron ore slimes generated during the beneficiation process carry considerable iron into the tailings. The slimes comprise particles of very fine sizes (-25µm) with high concentrations of impurities like alumina and silica and impose inefficient recoveries of iron bearing minerals. In this context reverse flotation studies are carried out with an emphasis to reduce iron loss in tails. Initial trials on spiral classifier overflow (COF) sample confirmed that the amine collector SOKEM 503C is comparatively more efficient than the SOKEM 522C and SOKEM 524C. To improve upon the grade and recoveries with the said collector, COF sample is subjected to two stage de-sliming followed by flotation. The outcome of study established that i) Improvement in product grade with the feed of narrow size range, ii) Iron bearing particle in finest size will have a tendency to migrate into froth fraction during initial stage of froth collection period, iii) Increased feed grade leads to increased iron loss in tailing and iv) Flotation on underflows of 5” and 3” cyclone independently, yields comparatively better grade and recoveries i.e. 63.0%Fe and 55.2% respectively rather than flotation separation on a blend of both the underflow of 5” and 3” hydrocyclone

The bed requirement inventory: a simple measure to estimate the need for a psychiatric bed.

OBJECTIVE: To develop an assessment of bed need that was as little affected by personal bias as possible. METHOD: The Bed Requirement Inventory (BRI) is an eight-point scale designed to identify the appropriate use of an acute psychiatric bed. This is completed by a member of the ward staff, usually a nurse, and takes 5 minutes to fill in. The reliability, validity and feasibility of using the scale in normal practice were tested in a one-year study, and variations in inappropriate bed use described. RESULTS: The inter-rater reliability of the scale was good (intra-class correlation coefficient = 0.63) and a comparison of the need for a psychiatric bed (comparing the BRI score with the judgement of an independent multidisciplinary group of professionals) also showed good agreement (k = 0.69), suggesting reasonable validity (although when the assessment was made by the named nurse agreement was less good). Results from a year-long survey in two West London hospitals showed that 17% of admissions were inappropriate and 32% had delayed discharge, black Caribbean patients had a significantly higher proportion (25%) of inappropriate admission than others (11%) and those referred from housing charities and hostels had a higher proportion (50%) of inappropriate bed use at some time than other groups (33%). CONCLUSIONS: The Bed Requirement Inventory is a quick and reliable method of determining the appropriate use of a psychiatric bed and could be of use in estimating local bed needs. Delayed discharge remains a serious reason for inappropriate bed use in London

Not Available

Not AvailableBACKGROUND Effects of supplementation of dried alkaline (referred to as MVP1) and aqueous (referred to as PBD1) extracts of K. alvarezii , were evaluated in broiler (Vencobb 400) chickens (1–35 d post‐hatch). In experiment I, each of the seven diets (basal diet with three levels (0.5, 1.5 or 5.0 g kg‐1 diet) of MVP1 or PBD1 and a negative control) was fed to twelve pen replicates containing five birds in each. In experiment II, each of three diets (a negative control, and PBD1 at two levels (1.0 or 1.5 g kg‐1 diet)) was fed to sixteen pen replicates of five chicks in each. RESULTS Concentrations of total phenolics, phycobillins and free radical scavenging activity were higher (P<0.01) whereas carrageenan was lower in PBD1 than in MVP1. In the experiment I, PBD1 at 1.5 g kg‐1 diet improved (P<0.05) body weight (7.11% higher). In the experiment II, both the treatments improved (P<0.01) BW (9.18% and 8.47%, respectively) as compared to control. The group fed with PBD1@ 1.0 g kg‐1 had higher (P<0.05) HI titre, expression of intestinal claudin 2, TLR2A, NOD1, avian beta defensin 4, interleukin 2 and 6 genes than control. Treatments did not influence feed efficiency or levels of most of the antioxidant enzymes. Villus width and crypt depth were significantly higher in the group fed with 1.5 g kg‐1 of PBD1. CONCLUSION Supplementing dried aqueous extract of Kappaphycus alvarezii at 1 g kg‐1 diet may be an effective strategy to increase growth and immunity in broiler chicken.Sea6 Energy Pvt Ltd, Bangalore, Indi