1,466 research outputs found
Evaporation Channel as a Tool to Study Fission Dynamics
The dynamics of the fission process is expected to affect the evaporation
residue cross section because of the fission hindrance due to the nuclear
viscosity. Systems of intermediate fissility constitute a suitable environment
for testing such hypothesis, since they are characterized by evaporation
residue cross sections comparable or larger than the fission ones. Observables
related to emitted charged particle, due to their relatively high emission
probability, can be used to put stringent constraints on models describing the
excited nucleus decay and to recognize the effects of fission dynamics. In this
work model simulations are compared with the experimental data collected via
the ^{32}S + ^{100}Mo reaction at E_{lab}= 200 MeV. By comparing an extended
set of evaporation channel observables the limits of the statistical model and
the large improvement coming by using a dynamical model are evidenced. The
importance of using a large angular covering apparatus to extract the
observable is stressed. The opportunity to measure more sensitive observables
by a new detection device in operation at LNL are also discussed.Comment: v1: 7 pages, 6 figure
Clustering effects in 48Cr composite nuclei produced via 24Mg + 24Mg reaction
In the framework of studying clustering effects in N=Z light nuclei, an experiment was carried out to get information on the properties of the 48 Cr composite nuclei produced via the 24 Mg +24 Mg reaction. In particular, the study regards the 48 Cr at 60 MeV of excitation energy where a resonance with a narrow width (170 KeV) has been found by measuring the elastic and anelastic channels. To determine the deformation of this state, evaporative Light Charged Particles (LCP) are measured and compared to the Statistical Model (SM) predictions, which are very sensitive to nuclear deformation. The experiment was performed at LNL using the 8ĒLP apparatus to select LCPs and a Parallel Plate Avalanche Counter (PPAC) system to detect the Evaporation Residues (ER). Preliminary results on the measurements of ER – LCP and LCP – LCP angular correlations are presented which indicate the presence of a very large deformation.The analysis will proceed with the extraction of the LCP energy spectra and with the angular correlations for high multiplicity channels to determine the deformation
Examination of isospin effects in multi-dimensional Langevin fission dynamics
Abstract One-dimensional and three-dimensional dynamical fission calculations based on Langevin equations are performed for the compound nuclei 194 Pb, 200 Pb, 206 Pb, 182 Hg, and 204 Hg to investigate the influence of the compound nucleus isospin on the prescission particle multiplicities and on the fission fragment mass–energy distribution. It is found that the prescission neutron, proton, and alpha particle multiplicities have approximately the same sensitivity to the dissipation strength for a given nucleus. This is at variance with conclusions of recent papers. The sensitivity of the calculated prescission particle multiplicities to the dissipation strength becomes higher with decreasing isospin of fissioning compound nucleus, and the increase of prescission particle multiplicities could reach 200%, when the reduction coefficient of one-body viscosity k s increases from 0.1 to 1, for the most neutron deficient nuclei considered. The variances of fission fragment mass and kinetic energy distributions are less sensitive to the change of dissipation strength than the prescission light particle multiplicities. A comparison to experimental data concerning 200 Pb nucleus is also presented
Examination of isospin effects in multi-dimensional Langevin fission dynamics
One-dimensional and three-dimensional dynamical fission calculations based on Langevin equations are performed for the compound nuclei Pb-194, Pb-200, Pb-206, Hg-182, and Hg-204 to investigate the influence of the compound nucleus isospin on the prescission particle multiplicities and oil the fission fragment mass-energy distribution It is found that the prescission neutron, proton, and alpha particle multiplicities have approximately the same sensitivity to the dissipation strength for a given nucleus This is at variance with Conclusions of recent papers The sensitivity of the calculated prescission particle Multiplicities to the dissipation strength becomes higher with decreasing isospin of fissioning compound nucleus, and the increase of prescission particle multiplicities could reach 200%, when the reduction coefficient of one-body viscosity k(s) increases from 0 1 to 1, for the most neutron deficient nuclei considered The variances of fission fragment mass and kinetic energy distributions are less sensitive to the change of dissipation strength than the prescission light particle multiplicities A comparison to experimental data concerning Pb-200 nucleus is also presented
Modulation of Neuropathic and Inflammatory Pain by the Endocannabinoid Transport Inhibitor AM404 [ N
Characterization of New TRPM8 Modulators in Pain Perception
Background: Transient Receptor Potential Melastatin-8 (TRPM8) is a non-selective cation channel activated by cold temperature and by cooling agents. Several studies have proved that this channel is involved in pain perception. Although some studies indicate that TRPM8 inhibition is necessary to reduce acute and chronic pain, it is also reported that TRPM8 activation produces analgesia. These conflicting results could be explained by extracellular Ca2+-dependent desensitization that is induced by an excessive activation. Likely, this effect is due to phosphatidylinositol 4,5-bisphosphate (PIP2) depletion that leads to modification of TRPM8 channel activity, shifting voltage dependence towards more positive potentials. This phenomenon needs further evaluation and confirmation that would allow us to understand better the role of this channel and to develop new therapeutic strategies for controlling pain.
Experimental approach: To understand the role of TRPM8 in pain perception, we tested two specific TRPM8-modulating compounds, an antagonist (IGM-18) and an agonist (IGM-5), in either acute or chronic animal pain models using male Sprague-Dawley rats or CD1 mice, after systemic or topical routes of administration.
Results: IGM-18 and IGM-5 were fully characterized in vivo. The wet-dog shake test and the body temperature measurements highlighted the antagonist activity of IGM-18 on TRPM8 channels. Moreover, IGM-18 exerted an analgesic effect on formalin-induced orofacial pain and chronic constriction injury-induced neuropathic pain, demonstrating the involvement of TRPM8 channels in these two pain models. Finally, the results were consistent with TRPM8 downregulation by agonist IGM-5, due to its excessive activation.
Conclusions: TRPM8 channels are strongly involved in pain modulation, and their selective antagonist is able to reduce both acute and chronic pain
Fission Dynamics: The Quest of a Temperature Dependent Nuclear Viscosity
oai:ojs2.jnp.chitkara.edu.in:article/2This paper presents a journey within some open questions about the current use of a temperature dependent nuclear viscosity in models of nuclear fission and proposes an alternative experimental approach by using systems of intermediate fissility. This study is particularly relevant because: i) systems of intermediate fissility offer a suitable frame-work since the intervals between the compound nucleus and scission point temperatures with increasing excitation energy are much smaller than in the case of heavier systems, ii) the dependence of viscosity on the temperature may change with the fissility of the composite system; iii) the opportunity to measure also observables in the evaporation residues channel translates into a larger set of effective constraints for the models
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