Error propagation in the rocket grenade experiment

Error propagation in rocket-grenade experimen

Measurements of the structure and circulation of the stratosphere and mesosphere, 1971-2

Complete data from a total of 43 meteorological rocket soundings of the stratosphere and mesosphere conducted from Barrow, Alaska; Churchill, Canada; Wallops Island Va.; and Kourou, French Guiana are presented. These data consist of temperature, pressure, density, and wind profiles from 35 acoustic grenade soundings that cover the 30 to 90 km altitude range, and temperature, pressure, and density profiles from 8 pitot probe soundings that cover the 25 to 120 km altitude range. Errors for each of the 35 acoustic grenade soundings are also included

Discovery of new 19.9-GHz methanol masers in star-forming regions

We have used the NASA Tidbinbilla 70-m antenna to search for emission from the 21-30 E (19.9-GHz) transition of methanol. The search was targeted towards 22 star formation regions that exhibit maser emission in the 107.0-GHz 31-40 A+ methanol transition, and in the 6.6-GHz 51-60 A+ transition characteristic of class II methanol maser sources. A total of seven sources were detected in the 21-30 E transition, six of these being new detections. Many of the new detections are weak (≳0.5 Jy), however, they appear to be weak masers rather than thermal or quasi-thermal emission. We find a strong correlation between sources that exhibit 19.9-GHz methanol masers and those that both have the class II methanol masers projected against radio continuum emission and have associated 6035-MHz OH masers. This suggests that the 19.9-GHz methanol masers arise in very specific physical conditions, probably associated with a particular evolutionary phase. In the model of Cragg, Sobolev & Godfrey these observations are consistent with gas temperatures of 50 K, dust temperatures of 150-200 K and gas densities of 106.5-107.5 cm-3

Gridmapping the northern plains of Mars: Geomorphological, Radar and Water-Equivalent Hydrogen results from Arcadia Plantia

A project of mapping ice-related landforms was undertaken to understand the role of sub-surface ice in the northern plains. This work is the first continuous regional mapping from CTX (“ConTeXt Camera”, 6 m/pixel; Malin et al., 2007) imagery in Arcadia Planitia along a strip 300 km across stretching from 30°N to 80°N centred on the 170° West line of longitude. The distribution and morphotypes of these landforms were used to understand the permafrost cryolithology. The mantled and textured signatures occur almost ubiquitously between 35° N and 78° N and have a positive spatial correlation with inferred ice stability based on thermal modelling, neutron spectroscopy and radar data. The degradational features into the LDM (Latitude Dependent Mantle) include pits, scallops and 100 m polygons and provide supporting evidence for sub-surface ice and volatile loss between 35-70° N in Arcadia with the mantle between 70-78° N appearing much more intact. Pitted terrain appears to be much more pervasive in Arcadia than in Acidalia and Utopia suggesting that the Arcadia study area had more wide-spread near-surface sub-surface ice, and thus was more susceptible to pitting, or that the ice was less well-buried by sediments. Correlations with ice stability models suggest that lack of pits north of 65-70° N could indicate a relatively young age (~1Ma), however this could also be explained through regional variations in degradation rates. The deposition of the LDM is consistent with an airfall hypothesis however there appears to be substantial evidence for fluvial processes in southern Arcadia with older, underlying processes being equally dominant with the LDM and degradation thereof in shaping the landscape

Outcomes of Cardiac Screening in Adolescent Soccer Players.

BACKGROUND: Reports on the incidence and causes of sudden cardiac death among young athletes have relied largely on estimated rates of participation and varied methods of reporting. We sought to investigate the incidence and causes of sudden cardiac death among adolescent soccer players in the United Kingdom. METHODS: From 1996 through 2016, we screened 11,168 adolescent athletes with a mean (±SD) age of 16.4±1.2 years (95% of whom were male) in the English Football Association (FA) cardiac screening program, which consisted of a health questionnaire, physical examination, electrocardiography, and echocardiography. The FA registry was interrogated to identify sudden cardiac deaths, which were confirmed with autopsy reports. RESULTS: During screening, 42 athletes (0.38%) were found to have cardiac disorders that are associated with sudden cardiac death. A further 225 athletes (2%) with congenital or valvular abnormalities were identified. After screening, there were 23 deaths from any cause, of which 8 (35%) were sudden deaths attributed to cardiac disease. Cardiomyopathy accounted for 7 of 8 sudden cardiac deaths (88%). Six athletes (75%) with sudden cardiac death had had normal cardiac screening results. The mean time between screening and sudden cardiac death was 6.8 years. On the basis of a total of 118,351 person-years, the incidence of sudden cardiac death among previously screened adolescent soccer players was 1 per 14,794 person-years (6.8 per 100,000 athletes). CONCLUSIONS: Diseases that are associated with sudden cardiac death were identified in 0.38% of adolescent soccer players in a cohort that underwent cardiovascular screening. The incidence of sudden cardiac death was 1 per 14,794 person-years, or 6.8 per 100,000 athletes; most of these deaths were due to cardiomyopathies that had not been detected on screening. (Funded by the English Football Association and others.)

Hsp21potentiates antifungal drug tolerance in Candida albicans

Peer reviewedPublisher PD

Device Optimization of Tris-Aluminum (Alq3) Based Bilayer Organic Light Emitting Diode Structures

In this work we present detailed analysis of the emitted radiation spectrum from tris(8-hydroxyquinoline) aluminum (Alq3) based bilayer OLEDs as a function of: the choice of cathode, the thickness of organic layers, and the position of the hole transport layer/Alq3 interface. The calculations fully take into account dispersion in the glass substrate, the indium tin oxide anode, and in the organic layers, as well as the dispersion in the metal cathode. Influence of the incoherent transparent substrate (1 mm glass substrate) is also fully accounted for. Four cathode structures have been considered: Mg/Ag, Ca/Ag, LiF/Al, and Ag. For the hole transport layer, N,N'-diphenyl-N,N'-(3-methylphenyl)-1,1'-biphenyl-4,4'-diamine (TPD) and N,N'-di(naphthalene-1-yl)-N,N'-diphenylbenzidine (NPB) were considered. As expected, emitted radiation is strongly dependent on the position of the emissive layer inside the cavity and its distance from the metal cathode. Although our optical model for an OLED does not explicitly include exciton quenching in vicinity of the metal cathode, designs placing the emissive layer near the cathode are excluded to avoid unrealistic results. Guidelines for designing devices with optimum emission efficiency are presented. Finally, several different devices were fabricated and characterized and experimental and calculated emission spectra were compared

Small but crucial : the novel small heat shock protein Hsp21 mediates stress adaptation and virulence in Candida albicans

Peer reviewedPublisher PD

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast

Acknowledgments We thank Rebecca Shapiro for creating CaLC1819, CaLC1855 and CaLC1875, Gillian Milne for help with EM, Aaron Mitchell for generously providing the transposon insertion mutant library, Jesus Pla for generously providing the hog1 hst7 mutant, and Cathy Collins for technical assistance.Peer reviewedPublisher PD

Greater risk of incident asthma cases in adults with Allergic Rhinitis and Effect of Allergen Immunotherapy: A Retrospective Cohort Study

Asthma and rhinitis are often co-morbid conditions. As rhinitis often precedes asthma it is possible that effective treatment of allergic rhinitis may reduce asthma progression. The aim of our study is to investigate history of allergic rhinitis as a risk factor for asthma and the potential effect of allergen immunotherapy in attenuating the incidence of asthma. Hospital-referred non-asthmatic adults, aged 18–40 years between 1990 and 1991, were retrospectively followed up until January and April 2000. At the end of follow up, available subjects were clinically examined for asthma diagnosis and history of allergen specific immunotherapy, second-hand smoking and the presence of pets in the household. A total of 436 non-asthmatic adults (332 subjects with allergic rhinitis and 104 with no allergic rhinitis nor history of atopy) were available for final analyses. The highest OR (odds ratio) associated with a diagnosis of asthma at the end of follow-up was for the diagnosis of allergic rhinitis at baseline (OR, 7.8; 95%CI, 3.1–20.0 in the model containing the covariates of rhinitis diagnosis, sex, second-hand smoke exposure, presence of pets at home, family history of allergic disorders, sensitization to Parietaria judaica; grass pollen; house dust mites; Olea europea: orchard; perennial rye; and cat allergens). Female sex, sensitization to Parietaria judaica and the presence of pets in the home were also significantly predictive of new onset asthma in the same model. Treatment with allergen immunotherapy was significantly and inversely related to the development of new onset asthma (OR, 0.53; 95%CI, 0.32–0.86). In the present study we found that allergic rhinitis is an important independent risk factor for asthma. Moreover, treatment with allergen immunotherapy lowers the risk of the development of new asthma cases in adults with allergic rhinitis