53 research outputs found
Bioinformatics and molecular modeling in glycobiology
The field of glycobiology is concerned with the study of the structure, properties, and biological functions of the family of biomolecules called carbohydrates. Bioinformatics for glycobiology is a particularly challenging field, because carbohydrates exhibit a high structural diversity and their chains are often branched. Significant improvements in experimental analytical methods over recent years have led to a tremendous increase in the amount of carbohydrate structure data generated. Consequently, the availability of databases and tools to store, retrieve and analyze these data in an efficient way is of fundamental importance to progress in glycobiology. In this review, the various graphical representations and sequence formats of carbohydrates are introduced, and an overview of newly developed databases, the latest developments in sequence alignment and data mining, and tools to support experimental glycan analysis are presented. Finally, the field of structural glycoinformatics and molecular modeling of carbohydrates, glycoproteins, and protein–carbohydrate interaction are reviewed
Seizing the moment: The presidential campaigns’ use of Twitter during the 2012 electoral cycle
High evolutionary divergence of the 5.8S ribosomal DNA in Mimulus glaucescens (Scrophulariaceae)
Identification and Assessing the Cultivars of Laminaria Lamx. (Phaeophyceae) with Molecular Markers
Bases anatomiques de l'abord chirurgical du segment distal de l'a. cérébrale postérieure
Analyzing the availability and performance of an e-health system integrated with edge, fog and cloud infrastructures
Loss of photosynthetic and chlororespiratory genes from the plastid genome of a parasitic flowering plant
Phylogenetic analysis of Sorghum and related taxa using internal transcribed spacers of nuclear ribosomal DNA
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