Application of Electric Field to Developing Falling Films using Wire-Plate Electrode Configuration- An Experimental Study

Experimental investigation of Electrohydrodynamic developing falling film flow of transformer oil has been conducted within an inclined rectangular channel and hydrodynamic characteristics of the flow have been revealed. The electric field has been generated by five overhead thin wire electrodes connected to the positive high DC voltage on the air and the grounded plate electrodes which are placed upon the floor of the channel. It is the first time that the wavy behavior on a liquid falling film's interface has been created by this electrode configuration. A non-intrusive method has been used to measure the local flow structure by a high-speed camera, then statistical characteristics of the wavy falling film have been computed by image processing of the captured video frames. By applying 13-16 kV to the wire electrodes, the influence of EHD force on the wavy behavior of falling film has been conducted for Reynolds number 10-120 in the laminar-wavy regime at three different inclination angles 15◦, 30◦ and 45°. The vertical distance of the high-voltage wire electrodes to ground electrodes has been set to 14 mm. The liquid velocity, film thickness, and wave frequency have been measured for non-electrified and electrified falling film, and their results have been evaluated with other experimental studies and an acceptable agreement has been obtained. The results indicate that the proposed HV wire-grounded plate electrode configuration in this study does not disturb the original structure of the falling film and by intensifying the wavy behavior of laminar falling film can either suppress or enhance heat/mass transfer rate. The effects of the applied voltage on the frequency, velocity and film thickness of the falling liquid film have been also discussed in detail

Predicting one-year left ventricular mass index regression following transcatheter aortic valve replacement in patients with severe aortic stenosis: A new era is coming

Aortic stenosis (AS) is the most common valvular heart disease in the western world, particularly worrisome with an ever-aging population wherein postoperative outcome for aortic valve replacement is strongly related to the timing of surgery in the natural course of disease. Yet, guidelines for therapy planning overlook insightful, quantified measures from medical imaging to educate clinical decisions. Herein, we leverage statistical shape analysis (SSA) techniques combined with customized machine learning methods to extract latent information from segmented left ventricle (LV) shapes. This enabled us to predict left ventricular mass index (LVMI) regression a year after transcatheter aortic valve replacement (TAVR). LVMI regression is an expected phenomena in patients undergone aortic valve replacement reported to be tightly correlated with survival one and five year after the intervention. In brief, LV geometries were extracted from medical images of a cohort of AS patients using deep learning tools, and then analyzed to create a set of statistical shape models (SSMs). Then, the supervised shape features were extracted to feed a support vector regression (SVR) model to predict the LVMI regression. The average accuracy of the predictions was validated against clinical measurements calculating root mean square error and R2 score which yielded the satisfactory values of 0.28 and 0.67, respectively, on test data. Our work reveals the promising capability of advanced mathematical and bioinformatics approaches such as SSA and machine learning to improve medical output prediction and treatment planning

О закономерностях распределения гелия в осадочном чехле юго-востока Беларуси

In this work, microscopic and histological studies suggest that Strobilanthes crispus ethanol extract reduce azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. S. crispus is considered a traditional medicine and used as an antioxidant. Its leaf contains a large amount of phenolic compounds to which its radical scavenging role is attributed and enhance its ability to eradicate oxidative stress reactions. The study was designed to determine the chemopreventive effect of S. crispus ethanol extract in vivo and in vitro by elucidating the effect of the extract on intermediate biomarkers which can be used as effective predictors of colon cancer. S. crispus was analyzed for DPPH free radical scavenging, nitric oxide (NO) and ferric acid reduction. The results indicated that S. crispus oral administration significantly inhibited colorectal carcinogenesis induced by AOM as revealed by the reduction in the number of ACF. S. crispus down-regulated the expression of PCNA, Bcl2 and beta-catenin. Additionally, it exerted a pronounced inhibitory effect on MDA and NO levels and stimulatory effect on CAT and GPx activities. These results demonstrate that S. crispus is a chemopreventive agent for colorectal cancer through the suppression of early and intermediate carcinogenic phases that may be related to its flavonoid content

Source Process and Slip Model of 2005 Dahuiyeh-Zarand Earthquake (Iran) Using Inversion of Near-Field Strong Motion Data

On 2005 February 22, the Dahuiyeh-Zarand earthquake, Mw 6.5, struck one of the most seismically active regions in south-central Iran, east of Zarand City in Kerman province,causing more than 500 fatalities. The causative fault of the 2005 Dahuiyeh-Zarand earthquake, a reverse fault, striking nearly EW and dipping to the north, was located within a mountainous region and therefore more difficult to identify compared to the range-bounded faults. Its identification, after the 2005 event, is very important for both the estimation of seismic hazard as well as for the damage and fatality functions. We have inverted six three-component nearfield strong motion waveforms to obtain the complete earthquake rupture history and slip distribution. Accelerograms are bandpass filtered with 0.2\u20131.0 Hz, and a length of 15\u201317 s of the waveforms is inverted. The lack of absolute timing has been successfully overcome by estimating, from the velocity model of the region, the propagation of P and S waves from the epicentre to the stations. The final fault slip model and the estimated source parameters are able to explain the observed waveforms. The rupture is found to be bilateral with a maximum slip of 2.4 m concentrated on two asperities in the west and east sides of the nucleation point at depths of 6\u201312 km. The western asperity is located to the east of Zarand City and beneath the Dahuiyeh village, which might explain why the Dahuiyeh village was totally destroyed by this earthquake

Chemopreventive effects of Strobilanthes crispus leaf extract on azoxymethane-induced aberrant crypt foci in rat colon

In this work, microscopic and histological studies suggest that Strobilanthes crispus ethanol extract reduce azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) in rats. S. crispus is considered a traditional medicine and used as an antioxidant. Its leaf contains a large amount of phenolic compounds to which its radical scavenging role is attributed and enhance its ability to eradicate oxidative stress reactions. The study was designed to determine the chemopreventive effect of S. crispus ethanol extract in vivo and in vitro by elucidating the effect of the extract on intermediate biomarkers which can be used as effective predictors of colon cancer. S. crispus was analyzed for DPPH free radical scavenging, nitric oxide (NO) and ferric acid reduction. The results indicated that S. crispus oral administration significantly inhibited colorectal carcinogenesis induced by AOM as revealed by the reduction in the number of ACF. S. crispus down-regulated the expression of PCNA, Bcl2 and beta-catenin. Additionally, it exerted a pronounced inhibitory effect on MDA and NO levels and stimulatory effect on CAT and GPx activities. These results demonstrate that S. crispus is a chemopreventive agent for colorectal cancer through the suppression of early and intermediate carcinogenic phases that may be related to its flavonoid content