Heritability of anthropometric phenotypes in caste populations of Visakhapatnam, India

This is the publisher's version, also available electronically from http://digitalcommons.wayne.edu/humbiol/vol74/iss3/1/.In this study, we used anthropometric data from six Andhra caste populations to examine heritability patterns of 23 anthropometric phenotypes (linear, craniofacial, and soft tissue measures) with special reference to caste differences. We obtained anthropometric data from 342 nuclear families from Brahmin, Reddy, Telaga, Nagara, Ag. Kshatriya, and Mala castes of Visakhapatnam, India. These caste groups represent the existing hierarchical stratification of Indian populations. We used a variance components approach to determine the heritability (h2) of these 23 anthropometric phenotypes (height, weight, BMI, etc.). The sample consisted of 1918 individuals ranging in age from 6 to 72 years (mean = 21.5, S.D. = 13.8). The heritabilities (h2 ± S.E.) for all anthropometric traits for the entire sample were significant (p < 0.0001) and varied from 0.25 ± 0.05 (BMI) to 0.61 ± 0.05 (bizygomatic breadth) after accounting for sex, age, and caste effects. Since data on socioeconomic and nutritional covariates were available for a subset of families, we repeated the genetic analyses using this subset, which has yielded higher heritabilities ranging from 0.21 ± 0.16 (head breadth) to 0.72 ± 0.18 (nasal breadth). In general, craniofacial measurements exhibited higher h2 compared to linear measures. Breadth measurements and circumferences yielded more or less similar heritabilities. Age and sex effects were significant (p < 0.0001) for most of the traits, while the effects of caste, socioeconomic status, and nutritional status were inconsistent across the traits. In conclusion, anthropometric phenotypes examined in this study are under appreciable additive genetic influences

Factor V Leiden mutation: An added risk in single ventricle palliation

We present the case report of a child with Factor V Leiden mutation who underwent Fontan procedure. Thromboembolism is a widely recognized complication of the Fontan procedure and its modifications. Factor V Leiden mutation, being a hypercoagulable state, posed a higher risk for thromboembolism in this child. Appropriate measures taken before and after surgery prevented postoperative coagulopathy

Synthesis, Characterization of Pendimethalin Encapsulated PVA Nanofiber and Its Impact on Blackgram

Nanotechnology operates at the nanoscale, offering precise manipulation and enhancing materials, applications, and performance across various domains. It holds promise in addressing weed-related losses, with nanofibers emerging as a noteworthy option among diverse nano-formulations. The research conducted at Centre for Agricultural Nanotechnology, TNAU, Coimbatore focuses on crafting pendimethalin-loaded PVA nanofibers. The nanofiber structure and successful pendimethalin integration were examined using SEM and FTIR analyses. Coating black gram seeds with pendimethalin-infused PVA nanofibers were assessed for their impact on growth and germination. SEM data indicated a rise in fibre diameter post-loading in PVA nanofiber-coated seeds (from 118.3 nm to 332.9 nm) and in pendimethalin-loaded PVA nanofiber coated seeds (from 339.8 nm to 664.5 nm). FTIR results validated pendimethalin presence within PVA nanofibers. Germination test demonstrated that herbicide-loaded nanofiber coatings didn't hinder germination or growth. In summary, synthesizing herbicide-loaded nanofibers and their seed coating presents a pioneering concept, warranting further exploration for its potential in weed seed germination and control

Heritability of Anthropometric Phenotypes in Caste Populations of Visakhapatnam, India

In this study, we used anthropometric data from six Andhra caste populations to examine heritability patterns of 23 anthropometric phenotypes (linear, craniofacial, and soft tissue measures) with special reference to caste differences. We obtained anthropometric data from 342 nuclear families from Brahmin, Reddy, Telaga, Nagara, Ag. Kshatriya, and Mala castes of Visakhapatnam, India. These caste groups represent the existing hierarchical stratification of Indian populations. We used a variance components approach to determine the heritability (h2) of these 23 anthropometric phenotypes (height, weight, BMI, etc.). The sample consisted of 1918 individuals ranging in age from 6 to 72 years (mean = 21.5, S.D. = 13.8). The heritabilities (h2 ± S.E.) for all anthropometric traits for the entire sample were significant (p \u3c 0.0001) and varied from 0.25 ± 0.05 (BMI) to 0.61 ± 0.05 (bizygomatic breadth) after accounting for sex, age, and caste effects. Since data on socioeconomic and nutritional covariates were available for a subset of families, we repeated the genetic analyses using this subset, which has yielded higher heritabilities ranging from 0.21 ± 0.16 (head breadth) to 0.72 ± 0.18 (nasal breadth). In general, craniofacial measurements exhibited higher h2 compared to linear measures. Breadth measurements and circumferences yielded more or less similar heritabilities. Age and sex effects were significant (p \u3c 0.0001) for most of the traits, while the effects of caste, socioeconomic status, and nutritional status were inconsistent across the traits. In conclusion, anthropometric phenotypes examined in this study are under appreciable additive genetic influences