Crystal structure of (1a,2,3a,4,5a,12a,13,14a,15,16a,17,18a,25a,26)-N-(2-Methoxyethyl)-5,12,18,25-tetraphenyl-27,28,29,30-tetraoxadeca-cyclo

Abstrac

Crystal structure of (1a, 8a, 9b, 12b)-1,8-diphenyl-13-oxatetracyclo-[6.4.1.0 2,7.0 9,12] trideca-2,4,6,10-tetraene, c24h18o

C24H18O, orthorhombic. Pbca (No. 61), a + 19.8704 A. b = 16.78(2) A, c = 10.520(6) A, V = 3507.6 A3, Z = 8, Rgt(F) = 0.057, wRref(F2) = 0.147, T = 293 K. Source of material. Colourless crystals were obtained from the slow evaporation of a methanol solution of the compound [1]. Experimental details. The C-bound H atoms were placed in their geometrically calculated positions and included in the final refinement in the riding model approximation. Discussion. The structure determination shows that the molecule approximates mm symmetry and that the phenyl groups are oriented in to the same side of the molecule as the 03 atom

Crystal structure of (1SR,8RS,15SR,19RS)4,6-dimethoxy-17-methyl-3,5-diazapentacyclo[6.6.5.02,7.09,14.015,19]-nonadec-2,4,6,9,11,13-hexaene-16,18-dione, C19H17N3O4, the major adduct from the Diels-Alder reaction of maleic anhydride with 2,4-dimethoxy-1,3-diazaanthracene

The H atoms were placed in their geometrically calculated positions and included in the final refinement in the riding model approximation

Crystal structure of dimethyl (1a,2b,3a,4b,7b,8a,9b,10a)-13-isopropylidene-pentacyclo[8.2.1.1.4,7.02,9.03,8]tetradeca-5,11-diene-2,9-dicarboxylate, c21h24o4

C21H2404. monoclinic, Pl2]/nl (No. 14). a = 9.547(2) A, b = 19.014(3) A, c = 9.877(2) A, ~ = 91.42(2)°, V = 1792.4 A3, Z = 4, Rgt(F) = 0.062, wRret(F2) = 0.194, T= 293 K

Crystal structure of (3s*,4s*)-4-hydroxy-2-(2'methoxyethyl)-3-phenyl-3-4-dihydroisoquinol-1(2h)-one, c18h19no3

C18H19NO3, monoclinic, P121/n1 (No. 14), a+8.454(6) A, b=13.123(3) A, c=14.698(3)A,P=104.85(3)o, V=1576.2 A3, Z=4, Rgt(F)=0.062, wRref(F2)=0.184, T=293 K. Source of material. This compound was prepared by the method described in the previous paper [1] but replacing the 3,4-dihydroisoquinoline with N(2'-methoxyethyl)-bezaldimine (0.815 g, 5mmol). Following chromatography, the product was isolated and recrystallised from ethanol in 13% yield (mp 407 K - 407.5 K). The product was characterised by a 3J coupling between the cis-related protons H-3 and H-4 of 6.9 Hz[2]. Experimental details The H atoms were placed in their geometrically calculated positions and included in the final refinement in the riding model approximation

Position-addressable nano-scaffolds. I. The preparation of N,O-, N,C- and N,N-bridged sesquinorbornadiene succinimides as compact, highly functionalized addressable building blocks

Succinimide-functionalized N,O-,N,C-, and N,N- bridged benzol[2] polynorbornanes (benzosesquinorboradienes) are reported for the first time and are prepared by the cycloaddition of either five-membered cyclie 1,3-diennes onto N-subsisted benzo-7-azanorboradienomaleimides or N-subsituted isoindoles onto the appropriate norbornadienomaleimides. These products containan end-fused norbornen (or a 7-substituted relative) and have been designed to act as alkene BLOCKs for the production of nano-scaffold with up to six addressable sites supplied byeach norbornrnr unit. The N-bridges in these BLOCKs (and their coupled products) allow N-substituent mobilityby invertomerization of the sp3 nitrogen whereas the N-substituents on the succinimides are attached to an sp2 nitrogen atom and remain static. Preferred invertomer geometry can be determined using molecular modelling

Crystal structure of tetramethyl (1a,2b,3a,5a,6b,7a,8b,9a,11a,12b)-4,10-dioxahexacyclo[5.5.1.02,6.03,5.08,12.09,11]tridecane-3,5,9,11-tetracarb-oxylate,c19h20o10

C19H200lO, monoclinic, P12]/cl (No. 14), a = 7.309(2) A b =12.471(3) A, c =20.930(7) A, p=95.96(2)°, V=1897.5 A3, Z =4, Rgt(F) =0.076, WRref(F2 ) =0.226, T =293 K

Crystal structure of (13s*,13ar*)-2,3-dimethoxy-13-hydroxy-13a-menthyl-8-oxo-5,6,13,13a-tetrahydro-8h-dibenzo[a,g]quinolizine, c20h21no4

C2oH21N04, monoclinic, PI21/c1 (No, 14), a = 7.521(2) A, b =23.257(2) ,c =9.784(2) A, f3 =95.57(2)°, V =1703.3 A, Z =4, Rgt(F) =0.060, 11·-RrcdF2) =0.183, T= 293 K

Crystal structure of dimethyl (1a,2b,3a,4b,7b,8a,9b,10a)-13-di(methylthio)methylidene-pentacyclo[8.2.1.14,7.02,9.03.8]tetradeca-5,11-diene-2,9-dicarboxylate, c21h24,o4s2

CZIHz404SZ, monoclinic, PI21/c1 (No. 14), a = 10.962(3) A, b = 12.797(2) A, c = 15.189(4) A, j3 = 1l0.]4(2t, V = 2000.5 A3, Z = 4, Rgl(F) = 0.046, wRreftr) = 0.1 ]9, T= 293 K

syn-Facial hetero-bridged [n]polynorbornanes : a new class of polarofacial framework molecules composed of fused 7-oxa- and 7-azanorbornanes

New oxygen-bridged norbornane-fused cyclobutene epoxides and bis-(cyclobutene epoxides) are described and shown to react stereoselectively with 7-azanorbornenes to produce syn-facial N,O-bridged polynorbornanes and stereorandomly with 7-oxanorbornenes to produce O,O-bridged polynorbornanes as mixtures of syn-facial and anti-facial products. Polarofacial systems containing up to six syn-facial norbornane bridges are described, while systems with seven co-facial oxygen atoms have been prepared by incorporating terminal epoxide rings to O5-[5]polynorbornanes. Ester-substituted 1,3,4-oxadiazoles are shown to be useful reagents for coupling 7-oxanorbornanes and produce predominantly syn-facial O-bridged polarofacial systems together with their anti-facial isomers