Análisis de viabilidad financiera empresa Distribuidora XYZ

Trabajo de InvestigaciónComo parte del objeto de este trabajo de investigación se recopiló la suficiente información sobre estudios de casos de viabilidad y diagnóstico financiero empresarial relacionados con el sector de autopartes y mantenimiento de vehículos. Se realizaron una serie de análisis y proyecciones financieras que nos ayudaron a establecer la viabilidad financiera de la empresa Distribuidora XYZ, la cual se constituyó hace ya dos años y cuenta con dos sucursales en la ciudad de BogotáIntroducción 1. Resumen 2. Marco teórico 3. Objetivos 4. Diseño metodológico 5. Cronograma de actividades 6. Resultados de la investigación 7. Conclusiones Bibliografía AnexosEspecializaciónEspecialista en Análisis y Administración Financier

Permutation entropy and irreversibility in gait kinematic time series from patients with mild cognitive decline and early Alzheimer’s dementia

Permutation entropy; Irreversibility; Mild cognitive impairmentEntropía de permutación; Irreversibilidad; Defecto cognitivo leveEntropia de permutació; Irreversibilitat; Deteriorament cognitiu lleuGait is a basic cognitive purposeful action that has been shown to be altered in late stages of neurodegenerative dementias. Nevertheless, alterations are less clear in mild forms of dementia, and the potential use of gait analysis as a biomarker of initial cognitive decline has hitherto mostly been neglected. Herein, we report the results of a study of gait kinematic time series for two groups of patients (mild cognitive impairment and mild Alzheimer’s disease) and a group of matched control subjects. Two metrics based on permutation patterns are considered, respectively measuring the complexity and irreversibility of the time series. Results indicate that kinematic disorganisation is present in early phases of cognitive impairment; in addition, they depict a rich scenario, in which some joint movements display an increased complexity and irreversibility, while others a marked decrease. Beyond their potential use as biomarkers, complexity and irreversibility metrics can open a new door to the understanding of the role of the nervous system in gait, as well as its adaptation and compensatory mechanisms.This research was funded through the Premio del Ilustre Colegio Profesional de Fisioterapeutas de la Comunidad De Madrid, prize number ICPFM-IX-2013

Permutation entropy and irreversibility in gait kinematic time series from patients with mild cognitive decline and early alzheimer’s dementia

Gait is a basic cognitive purposeful action that has been shown to be altered in late stages of neurodegenerative dementias. Nevertheless, alterations are less clear in mild forms of dementia, and the potential use of gait analysis as a biomarker of initial cognitive decline has hitherto mostly been neglected. Herein, we report the results of a study of gait kinematic time series for two groups of patients (mild cognitive impairment and mild Alzheimer’s disease) and a group of matched control subjects. Two metrics based on permutation patterns are considered, respectively measuring the complexity and irreversibility of the time series. Results indicate that kinematic disorganisation is present in early phases of cognitive impairment; in addition, they depict a rich scenario, in which some joint movements display an increased complexity and irreversibility, while others a marked decrease. Beyond their potential use as biomarkers, complexity and irreversibility metrics can open a new door to the understanding of the role of the nervous system in gait, as well as its adaptation and compensatory mechanismsThis research was funded through the Premio del Ilustre Colegio Profesional de Fisioterapeutas de la Comunidad De Madrid, prize number ICPFM-IX-201

Characterizing Normal and Pathological Gait through Permutation Entropy

Altres ajuts: We acknowledge the contribution of the children and their families who generously collaborated to build the gait dataset used in this study. We are also grateful to Michael R. Paul for kindly editing the English style of this manuscript. The acquisition and processing of gait data were funded by Escuela de Fisioterapia de la ONCE-UAM, through a private donation, and Agencia de Evaluación de Tecnologías Sanitarias (Instituto de Salud Carlos III), .Cerebral palsy is a physical impairment stemming from a brain lesion at perinatal time, most of the time resulting in gait abnormalities: the first cause of severe disability in childhood. Gait study, and instrumental gait analysis in particular, has been receiving increasing attention in the last few years, for being the complex result of the interactions between different brain motor areas and thus a proxy in the understanding of the underlying neural dynamics. Yet, and in spite of its importance, little is still known about how the brain adapts to cerebral palsy and to its impaired gait and, consequently, about the best strategies for mitigating the disability. In this contribution, we present the hitherto first analysis of joint kinematics data using permutation entropy, comparing cerebral palsy children with a set of matched control subjects. We find a significant increase in the permutation entropy for the former group, thus indicating a more complex and erratic neural control of joints and a non-trivial relationship between the permutation entropy and the gait speed. We further show how this information theory measure can be used to train a data mining model able to forecast the child's condition. We finally discuss the relevance of these results in clinical applications and specifically in the design of personalized medicine interventions

Gait phenotypes in paediatric hereditary spastic paraplegia revealed by dynamic time warping analysis and random forests

The Hereditary Spastic Paraplegias (HSP) are a group of heterogeneous disorders with a wide spectrum of underlying neural pathology, and hence HSP patients express a variety of gait abnormalities. Classification of these phenotypes May help in monitoring disease progression and personalizing therapies. This is currently managed by measuring values of some kinematic and spatio-temporal parameters at certain moments during the gait cycle, either in the doctor´s surgery room or after very precise measurements produced by instrumental gait analysis (IGA). These methods, however, do not provide information about the whole structure of the gait cycle. Classification of the similarities among time series of IGA measured values of sagittal joint positions throughout the whole gait cycle can be achieved by hierarchical clustering analysis based on multivariate dynamic time warping (DTW). Random forests can estimate which are the most important isolated parameters to predict the classification revealed by DTW, since clinicians need to refer to them in their daily practice. We acquired time series of pelvic, hip, knee, ankle and forefoot sagittal angular positions from 26 HSP and 33 healthy children with an optokinetic IGA system. DTW revealed six gait patterns with different degrees of impairment of walking speed, cadence and gait cycle distribution and related with patient’s age, sex, GMFCS stage, concurrence of polyneuropathy and abnormal visual evoked potentials or corpus callosum. The most important parameters to differentiate patterns were mean pelvic tilt and hip flexion at initial contact. Longer time of support, decreased values of hip extension and increased knee flexion at initial contact can differentiate the mildest, near to normal HSP gait phenotype and the normal healthy one. Increased values of knee flexion at initial contact and delayed peak of knee flexion are important factors to distinguish GMFCS stages I from II- III and concurrence of polyneuropathyDGA was in receipt of a grant from Sociedad Española de Neurología Pediátrica (SENEP). Publication fee was supported by EUF-ONCE-UAM and Asociación Española de Paraparesia Espástica Familiar (AEPEF)

Overview of processing techniques for surface electromyography signals

Surface electromyography (sEMG) is a technology to assess muscle activation, which is an important component in applications related to diagnosis, treatment, progression assessment, and rehabilitation of specific individuals' conditions. Recently, sEMG potential has been shown, since it can be used in a non-invasive manner; nevertheless, it requires careful signal analysis to support health professionals reliably. This paper briefly described the basic concepts involved in the sEMG, such as the physiology of the muscles, the data acquisition, the signal processing techniques, and classification methods that may be used to identify disorders or signs of abnormalities according to muscular patterns. Specifically, classification methods encompass digital signal processing techniques and machine learning with high potential in the field. We hope that this work serves as an introduction to researchers interested in this field.Comment: 11 pages, 7 figure

Despliegue de solución global de seguridad y servicios TI a la medida basados en Zentyal Server

Paso final de la migración y arranque de los requerimientos solicitados en relación con la administración y control de una distribución Linux para este caso Zentyal Server. Está orientada a la implementación de servicios de infraestructura IT de mayor nivel para Intranet y Extranet como son: DHCP Server, DNS Server, Controlador de Dominio, Proxy no transparente, Cortafuegos, File Server, Sprint Server y VPNFinal step of the migration and start of the requested requirements in relation to the administration and control of a Linux distribution for this case Zentyal Server. It is oriented to the implementation of higher-level IT infrastructure services for Intranet and Extranet such as: DHCP Server, DNS Server, Domain Controller, Non-transparent Proxy, Firewall, File Server, Print Server and VPN

Una revista para la comunidad científica internacional vinculada a la Ingeniería del Agua

Se destaca el carácter especial de este número, al ser el que sirve de inicio de esta nueva fase y de puente con la fase anterior.González Pérez, J.; Puertas Agudo, J.; Pulido Calvo, I.; Andrés Doménech, I.; Valdes, JB. (2014). Una revista para la comunidad científica internacional vinculada a la Ingeniería del Agua. Ingeniería del agua. 18(1):VI-VII. https://doi.org/10.4995/ia.2014.3291OJSVIVII18

Diseño de un grip para una ventosa cuyo uso sea alternable entre un robot colaborativo UR3 y un operario

El presente proyecto se centra en una propuesta de diseño de un grip para una ventosa que pueda ser utilizada tanto por un robot colaborativo UR3 como por un humano. Para llevar a cabo este diseño se deben tener en cuenta dos criterios principales: 1) requerimientos del humano y 2) especificaciones del robot. Inicialmente, en el proceso de diseño se tomarán las medidas de antropometría y fuerza a estudiantes universitarios; posteriormente, se realizará un bosquejo del prototipo del grip teniendo en cuenta las necesidades de los usuarios (humano y robot). A partir de esta información, se elaborará el diseño del dispositivo en un software CAD para realizar las pruebas de rendimiento y finalmente demostrar su funcionamiento mediante una animación desarrollada en AutoDesk 3ds Max.This project focuses on a design proposal for a grip for a suction cup that can be used by both a collaborative UR3 robot and a human. To carry out this design, two main criteria must be taken into account: 1) human requirements and 2) robot specifications. Initially, anthropometry and force measurements will be taken in the design process of university students; Subsequently, a sketch of the grip prototype will be made taking into account the needs of the users (human and robot). From this information, the design of the device will be elaborated in CAD software to perform performance tests and finally demonstrate its operation through an animation developed in AutoDesk 3ds Max.Ingeniero (a) IndustrialPregrad

Diagnóstico del Deterioro de la Vía que del Municipio del Líbano Tolima Conduce a la Vereda de Santa Teresa entre los kilómetros 5 y 6

Evaluar alternativas de solución al deterioro de la vía que comunica el centro poblado del Líbano Tolima y las veredas de la Trinidad, San Fernando, Tierradentro y Santa Teresa, en el tramo comprendido entre los kilómetros 5 y 6, durante la temporada invernal.El Líbano es un municipio ubicado al norte del departamento del Tolima, el cual presenta un atraso evidente en el mantenimiento de la malla vial rural, lo cual genera sobre costos en la producción agrícola de la región, por las dificultades de transporte de los productos al centro poblado. Motivo por el cual se llevo a cabo esta investigación con el fin de plantear una solución ‘Tipo’ para mejorar las condiciones de la vía, específicamente la que conduce del municipio del Líbano Tolima a la vereda de Santa Teresa, tomando como tramo de estudio el comprendido entre el k5 y k6, entre tanto, se hizo evidente que con el fin de llegar a una solución optima y de calidad, se planea un sistema constructivo de Placa Huella, de acuerdo a los lineamientos del INVIAS y del Departamento Nacional de Planeación del Gobierno Nacional para vias de tercer orden.Líbano is a municipality located in the north of the department of Tolima, which presents an evident delay in the maintenance of the rural road network, which generates extra costs in the agricultural production of the region, due to the difficulties of transporting the products to the population center. Reason why this research was carried out in order to propose a solution "Type" to improve the conditions of the road, specifically the one that leads from the municipality of Lebanon Tolima to the village of Santa Teresa, taking as a study section between the k5 and k6, meanwhile, it became clear that in order to reach an optimal solution and quality, it plans a constructive system of Footprint Plate, according to the guidelines of INVIAS and the National Department of Planning of the National Government for third order roads