GRB Spectral Hardness and Afterglow Properties

A possible relationship between the presence of a radio afterglow and gamma-ray burst spectral hardness is discussed. The correlation is marginally significant; the spectral hardness of the bursts with radio afterglows apparently results from a combination of the break energy Ebreak and the high-energy spectral index beta. If valid, this relationship would indicate that the afterglow does carry information pertaining to the GRB central engine.Comment: 5 pages, 3 figures, presented at the 5th Huntsville Gamma-Ray Burst Symposiu

A Simple BATSE Measure of GRB Duty Cycle

We introduce a definition of gamma-ray burst (GRB) duty cycle that describes the GRB's efficiency as an emitter; it is the GRB's average flux relative to the peak flux. This GRB duty cycle is easily described in terms of measured BATSE parameters; it is essentially fluence divided by the quantity peak flux times duration. Since fluence and duration are two of the three defining characteristics of the GRB classes identified by statistical clustering techniques (the other is spectral hardness), duty cycle is a potentially valuable probe for studying properties of these classes.Comment: 4 pages, 1 figure, presented at the 5th Huntsville Gamma-Ray Burst Symposiu

Multiscale patterning of nanocomposite polyelectrolyte/nanoparticle films using inkjet printing and AFM scratching

The fabrication of structured polymer/nanoparticle composite films through a combination of additive, subtractive and self-assembly methodologies is investigated. Consumer grade inkjet printing hardware is employed to deposit cationic polyelectrolytes on (i) hydrophilic and (ii) hydrophobised glass substrates. The hydrophobisation process controls the spreading of the droplets and hence the lateral size of printed features. The printed cationic polyelectrolyte regions are used as a template to direct the self-assembly of negatively charged gold nanoparticles onto the surface. Micro-scale features are created in the polyelectrolyte/nanoparticle films using AFM scratching to selectively displace material. The effect of substrate wettability on film morphology is discussed

Microplastic-free microcapsules using supramolecular self-assembly of bis-urea molecules at an emulsion interface

Encapsulation technology is well established for entrapping active ingredients within an outer shell for their protection and controlled release. However, many solutions employed industrially use nondegradable cross-linked synthetic polymers for shell formation. To curb rising microplastic pollution, regulatory policies are forcing industries to substitute the use of such intentionally added microplastics with environmentally friendly alternatives. This work demonstrates a one-pot process to make microplastic-free microcapsules using supramolecular self-assembly of bis-ureas. Molecular bis-urea species generated in-situ spontaneously self-assemble at the interface of an oil-in-water emulsion via hydrogen bonding to form a shell held together by noncovalent bonds. In addition, Laponite nanodiscs were introduced in the formulation to restrict aggregation observed during the self-assembly and to reduce the porosity of the shell, leading to well-dispersed microcapsules (mean Sauter diameter d [3,2] ∼ 5 μm) with high encapsulation efficiency (∼99%). Accelerated release tests revealed an increase in characteristic release time of the active by more than an order of magnitude after encapsulation. The mechanical strength parameters of these capsules were comparable to some of the commercial, nondegradable melamine–formaldehyde microcapsules. With mild operating conditions in an aqueous environment, this technology has real potential to offer an industrially viable method for producing microplastic-free microcapsules

Accurate micron-scale modification of AFM cantilevers

Atomic force microscopy has provided the modern researcher with the ability to perform accurate force measurements between a probe and a surface. The data obtained can be used in the development of biosensors, surfactants, and materials with enhanced properties, to name only a few applications. The atomic force microscope (AFM) is undoubtedly suited for making repeated force measurements. Standard AFM cantilevers can be modified through the attachment of a colloid probe such as silica, and employed in the analysis of forces between surfaces. Resin-based or glass bond adhesives are suitable for probe bonding, as they are insoluble in water once set. However, such adhesives often require heating to reduce their viscosity, which makes the procedure quite difficult to carry out. The particle is usually attached to the apex of the cantilever, so that measurements can be performed with optimum force resolution. Particle attachment is traditionally carried out under an optical microscope using thin wire as a guide. However, there is no guarantee that the colloid particle has been accurately positioned on the apex of the cantilever

Bio-nanopatterning of Surfaces

Bio-nanopatterning of surfaces is a very active interdisciplinary field of research at the interface between biotechnology and nanotechnology. Precise patterning of biomolecules on surfaces with nanometre resolution has great potential in many medical and biological applications ranging from molecular diagnostics to advanced platforms for fundamental studies of molecular and cell biology. Bio-nanopatterning technology has advanced at a rapid pace in the last few years with a variety of patterning methodologies being developed for immobilising biomolecules such as DNA, peptides, proteins and viruses at the nanoscale on a broad range of substrates. In this review, the status of research and development are described, with particular focus on the recent advances on the use of nanolithographic techniques as tools for biomolecule immobilisation at the nanoscale. Present strengths and weaknesses, as well future challenges on the different nanolithographic bio-nanopatterning approaches are discussed