Preparation and evaluation of herbal cream

A herbal fairness cream was formulated using herbal extracts which have potential antioxidant activity. Creams were basically formulated using the hydro alcoholic extracts of Glycyrrhiza glabra (root and Stolons),Camellia sinensis (leaf), Pleurotus osttreatus (mushroom plant). The prepared formulation were subjected to different evaluation like spreadability, pH, appearance, viscosity, drug content, irritability and antioxidant properties. The prepared formulation was found stable and effective. Among the several combination Liquorice & Green Tea based preparation shows better results. From the results it was concluded that it is possible to develop creams containing herbal extracts having potent antioxidant and fairness property and can be used as the provision of a barrier to protect skin.  &nbsp

Preparation and Quality Evaluation of Mozzarella Cheese from Different Milk Sources

Three mozzarella cheeses were prepared from three different milk sources i.e. cow (C), buffalo (B) and their mix (A) milks using DL (Streptococcus lactis and cremoris; S. Diacetalactic, Leuconostoc cremoris) and yoghurt cultures. Milk was standardized to C/F: 0.90/0.92 and process optimized for using all milk sources. The samples were analyzed for physico-chemical and functional properties, sensory attributes and protein and fat losses. Except ash and yield at 50% moisture; fat, protein, actual yield, pH, acidity and moisture were significantly influenced by milk sources. From sensory result, cow and mix cheeses were significantly superior, whereas functional properties were superior for cow cheese but buffalo and mix cheeses had higher nutritive value. From overall comparison, cow mozzarella cheese was ranked most suitable for pizza topping

Antihyperlipidemic potential of herbals

One of the most widespread diseases in the world is Coronary Heart Disease (CHD). It is also one of the most preventable. This review explores the management of CHD through changes in dietary modifications, lifestyle, and the use of dietary supplements and botanical

Clock gene variation in type 2 diabetes: a review

Diabetes mellitus type 2 is a long-standing metabolic disorder that is exemplify by high blood sugar, insulin resistance, and comparative lack of insulin. General symptoms include increased thirst, frequent urination, and unsolved weight loss. Type 2 diabetes is mainly due to obesity and not sufficient work out in public who are heritably prone. Circadian clocks are significant to keep the moment in the sequence of physiological practice, series of behaviour and metabolism. The plasma level of glucose and numerous hormones implicated in glucose homeostasis for example insulin and glucagon exhibit circadian variation. Circadian desynchrony, a feature of alter occupation elevated-fat diet feed and sleep distraction in individual have been linked with metabolic disorders for instance obesity and type 2 diabetes. Circadian rhythm distraction can cause different fitness disarray. Current reading has discovered a seal connection among the pathophysiology of metabolic condition, which is characterized by obesity and hyperglycemia, and the operation of interior molecular clock

A review of wound healing activity on different wound models

Wound is an injury of living tissue or break in the epithelial integrity of the upper layer of skin. This may lead to disturbance of skin anatomical structure and their function. The normal wounds start to heal immediately after an injury. Normal healing process involved: inflammatory phase, proliferation phase and maturation phase. Now a day wound healing is a challenging clinical problem. So, necessity of effective wound management is required. The various screening models play important role to understand the basic process of tissue repair and treatment of wounds. Wide varieties of in-vitro, ex-vivo and in-vivo models have been developed for evaluation of wound healing activity. The in-vitro models includes Chick chorioallantoic membrane assay, Fibroblast assay, Collagen assay, Scratch assay, Endothelial cell in vitro tube formation assay, Keratinocytes assay. Ex-vivo models includes organotypic culture, human ex vivo skin culture, porcine model, Human organotypic skin explanted culture and the  in-vivo models includes Excision wound model, Incision wound Model, Burn wound model, Dead space wound model.The aim of this review article is detailed study of different types of in-vitro, ex-vivo and in-vivo models for evaluation of wound healing activity

Factors affecting on compliance of childhood immunization in Ilam District of Nepal: a case-control study

Childhood immunization is one of the most important public health interventions to reduce child morbidity and mortality. Reaching all children with full immunization services is critical to meet Nepal's commitment to Sustainable Development Goals (SDGs). This study aimed to identify factors affecting compliance with childhood immunization in children aged 16 to 36 months in Nepal. A community-based unmatched case-control study was conducted with 250 (83 cases and 167 controls) respondents in the Ilam district of Nepal. Respondents were randomly selected using a multi-stage cluster sampling technique. Data were collected using a structured questionnaire and analysed using SPSS version 16 statistical software. Bivariate and multivariate logistic regression analyses were done to identify the factors influencing compliance with childhood immunization of the sampled respondents. More than two-thirds (66.8%) of the sampled children were fully immunized, and 19.3% of the children defaulted to the Measles-Rubella vaccines. Only 19.2% of the respondents had good knowledge about the type of vaccine, and more than half (59.2%) of the respondents had a positive attitude towards immunization. Multivariate logistic regression analysis revealed that lack of knowledge about vaccines (AOR = 49.4, 95% CI = 12.94 to 188.59), father's level of education (AOR = 2.1, 95% CI = 1.05 to 4.30), not getting immunization on the day of the appointment (AOR = 4.8, 95% CI =2.30 to 9.89), lack of knowledge about immunization schedule (AOR = 2.4, 95% CI = 1.14 to 4.84), and negative attitude towards immunization (AOR = 2.1, 95% CI = 1.03 to 4.19) were independently impeded on compliance on the childhood immunization. Targeted intervention in health promotion activities at the household level should be promoted and integrated immunization services into the existing primary health care services

Spatio-Temporal Impacts of Biofuel Production and Climate Variability on Water Quantity and Quality in Upper Mississippi River Basin

Impact of climate change on the water resources of the United States exposes the vulnerability of feedstock-specific mandated fuel targets to extreme weather conditions that could become more frequent and intensify in the future. Consequently, a sustainable biofuel policy should consider: (a) how climate change would alter both water supply and demand; and (b) in turn, how related changes in water availability will impact the production of biofuel crops; and (c) the environmental implications of large scale biofuel productions. Understanding the role of biofuels in the water cycle is the key to understanding many of the environmental impacts of biofuels. Therefore, the focus of this study is to model the rarely explored interactions between land use, climate change, water resources and the environment in future biofuel production systems. Results from this study will help explore the impacts of the US biofuel policy and climate change on water and agricultural resources. We used the Soil and Water Assessment Tool (SWAT) to analyze the water quantity and quality consequences of land use and land management related changes in cropping conditions (e.g., more use of marginal lands, greater residue harvest, increased yields), plus management practices due to biofuel crops to meet the Renewable Fuel Standard target on water quality and quantity

Fast Orthostatic Tremor in Parkinson’s Disease: Case Report and Comprehensive Review of Literature

Background: Orthostatic tremor (OT) is a rare symmetric tremor disorder occasionally observed in association with other movement disorders. Case report: We report the presence of a fast OT in a case of Parkinson’s disease (PD), and provide a comprehensive review of the literature. Discussion: A fast OT presenting as unsteadiness may be a presenting symptom of PD. This symptom may be nonresponsive to levodopa, and benzodiazepines should be prescribed to adequately control the OT and reduce disability

Effect of harvesting time and desapping on sapburn and quality in mango (Mangifera indica) cv. Langra

Sapburn is one of the most important problems in mango (Mangifera indica L.) which severely downgrade its quality and reduces its market value. In the present study, two experiments were conducted to study the effect of harvesting time on sap flow quantity; and its control through simple desapping treatment. The sap flow was recorded higher from the mango fruits (cv. Langra) harvested during morning hours. For the second experiment, mature mango fruits were harvested with 8 - 10 cm pedicel attached and treated with aqueous solutions of sodium hydroxide (1% and 2%) and potassium hydroxide (1% and 2%) by immersion method, after removing the pedicel. For control, sap was allowed to flow freely over the fruit surface. During storage of fruit at ambient condition (25±2°C) for 12 days, fruits desapped with 1% sodium hydroxide (NaOH) showed about 11-fold lower sapburn injury than control. Treatment with NaOH did not significantly affect TSS, acidity and carotenoids content in the fruit. However, it maintained significantly higher ascorbic acid, total phenolics content and antioxidant activity than control