A Sexier Literacy: Information Literacy through Media Literacy

The similarities in scope and objectives between information literacy and media literacy education are remarkable. On the surface, each is concerned with issues of access, analysis, evaluation, and use or production. But even beyond these basic tenets, guiding learners toward critical thought, creative agency, ethical use and production of information, and civic empowerment are shared concerns. In fact, as we begin to work with the generation of students dubbed Generation M by the Kaiser Family Foundation, we will increasingly find the distinctions between information and media literacies breaking down. Generation M, or the media generation, has grown up steeped in media exposure and with unprecedented access to technologies enabling information consumption and production. Recognizing and addressing the unique relationship this generation feels to media and information offers us an exciting opportunity to re-imagine information literacy instruction at the college level. Additionally, media literacy instruction invites librarians to forge dynamic working partnerships with professors, information technologists, and local media activists. While the term information literacy might alienate some potential allies, media studies scholarship is a familiar discipline for faculty and media-makers already working with film, television, journalism cyber-journalism, and digital media

Damage and protection cost curves for coastal floods within the 600 largest European cities

The economic assessment of the impacts of storm surges and sea-level rise in coastal cities requires high-level information on the damage and protection costs associated with varying flood heights. We provide a systematically and consistently calculated dataset of macroscale damage and protection cost curves for the 600 largest European coastal cities opening the perspective for a wide range of applications. Offering the first comprehensive dataset to include the costs of dike protection, we provide the underpinning information to run comparative assessments of costs and benefits of coastal adaptation. Aggregate cost curves for coastal flooding at the city-level are commonly regarded as by-products of impact assessments and are generally not published as a standalone dataset. Hence, our work also aims at initiating a more critical discussion on the availability and derivation of cost curves

Identification of Vascularised Carotid Plaques Using a Standardised and Reproducible Technique to Measure Ultrasound Contrast Uptake

ObjectivesContrast-enhanced ultrasonography (CEUS) has been used to assess the vascularisation of carotid plaques. Our aim was to develop and validate a standardised semi-automated method for CEUS examination of plaques, and test if the technique could be used to identify vulnerable plaques.MethodsStudy participants were a mixed population of symptomatic and asymptomatic subjects, selected if they had a plaque with height >2.5 mm and <10% acoustic shadowing. Participants received a bolus of ultrasound contrast agent and a 90-s cine-loop was captured. A Contrast Quantification Program (CQP) was developed and trained to identify extent of contrast uptake after motion correction and application of a noise reduction algorithm. The technique was validated by comparing CQP values with visual assessment of contrast uptake. CQP values were also compared with plaque echogenicity and history of clinical events.ResultsCQP values correlated with a visual, 5-scale classification of contrast uptake by two blinded, experienced sonographers. Repeated contrast injections showed high reproducibility. Participants with a history of ipsilateral stroke/TIA had significantly higher CQP values than asymptomatic participants.ConclusionWe present a reproducible, semi-automatic method to identify vascularisation of carotid plaques, which could be used in prospective studies to determine the clinical value of plaque vascularisation

The high energy gamma-ray emission expected from Tycho's supernova remnant

A nonlinear kinetic model of cosmic ray (CR) acceleration in supernova remnants (SNRs) is used to describe the properties of Tycho's SNR. Observations of the expansion characteristics and of the nonthermal radio and X-ray emission spectra, assumed to be of synchrotron origin, are used to constrain the overall dynamical evolution and the particle acceleration parameters of the system, in addition to what is known from independent estimates of the distance and thermal X-ray observations. It is shown that a very efficient production of nuclear cosmic rays, leading to strong shock modification, and a large downstream magnetic field strength B_d approx 240muG are required to reproduce the observed synchrotron emission from radio to X-ray frequencies. This field strength is still well within the upper bound for the effective magnetic field, consistent with the acceleration process. The pi^0-decay gamma-ray flux turns out to be somewhat greater than the inverse Compton (IC) flux off the Cosmic Microwave Background at energies below 1 TeV, dominating it strongly at 10 TeV. The predicted TeV gamma-ray flux is consistent with but close to the very low upper limit recently obtained by HEGRA. A future detection at E_gamma ~ 10 TeV would clearly indicate hadronic emission.Comment: 8 pages, 6 figures. Accepted in Astronomy and Astrophyic

Biogeochemical characterization of suspended particulate matter in the Columbia River estuary

In order to understand what controls the composition of suspended particulate material (SPM) in estuarine turbidity maxima (ETM), a set of SPM samples collected in the Columbia River and estuary (northwestern USA) during 3 seasons (fall 1990, summer 1991, spring 1992) was analyzed for detrital mineral (Min), total organic matter [OM, as 2 x particulate organic carbon (POC)], biogenic silica (BSi), chlorophyll a, δ¹³C, and lignin. In most samples, Min, OM and BSi collectively accounted for 100% of total SPM mass, although their relative importance changed seasonally. The ETM was a trap for organic matter during all 3 seasons, which can explain the intense microbial activity and microcrustacean grazing observed previously. The organic matter was particularly rich in chlorophyll a in late spring to early summer. The source of this seasonal enrichment was mainly riverine phytoplankton. The organic matter contribution to ETM from the ocean was minor compared to the river, but apparently not negligible. Despite large seasonal variations in chlorophyll content, the δ¹³C of POC concentrated in ETM remained nearly constant between -26 and -25.5%. Vascular plant debris, as depicted by lignin phenol content, always comprised a minor fraction of the organic matter in ETM, although ETM had higher lignin levels than the OM of surrounding waters. Intertidal mudflats are if not an additional source of organic matter at least an important site for transforming riverine organic matter that is ultimately concentrated in ETM.Keywords: Suspended particulate material (SPM), Lignin, Particulate organic carbon (POC), Columbia River estuary, Aluminum, Estuarine turbidity maxima (ETM), Mudflats, Chlorophyll, ManganeseArticle appears in Marine Ecology Progress Series and is copyrighted by Inter Research

Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.

Metastasis requires tumor cells to navigate through a stiff stroma and squeeze through confined microenvironments. Whether tumors exploit unique biophysical properties to metastasize remains unclear. Data show that invading mammary tumor cells, when cultured in a stiffened three-dimensional extracellular matrix that recapitulates the primary tumor stroma, adopt a basal-like phenotype. Metastatic tumor cells and basal-like tumor cells exert higher integrin-mediated traction forces at the bulk and molecular levels, consistent with a motor-clutch model in which motors and clutches are both increased. Basal-like nonmalignant mammary epithelial cells also display an altered integrin adhesion molecular organization at the nanoscale and recruit a suite of paxillin-associated proteins implicated in invasion and metastasis. Phosphorylation of paxillin by Src family kinases, which regulates adhesion turnover, is similarly enhanced in the metastatic and basal-like tumor cells, fostered by a stiff matrix, and critical for tumor cell invasion in our assays. Bioinformatics reveals an unappreciated relationship between Src kinases, paxillin, and survival of breast cancer patients. Thus adoption of the basal-like adhesion phenotype may favor the recruitment of molecules that facilitate tumor metastasis to integrin-based adhesions. Analysis of the physical properties of tumor cells and integrin adhesion composition in biopsies may be predictive of patient outcome

Prototyping of petalets for the Phase-II Upgrade of the silicon strip tracking detector of the ATLAS Experiment

In the high luminosity era of the Large Hadron Collider, the HL-LHC, the instantaneous luminosity is expected to reach unprecedented values, resulting in about 200 proton-proton interactions in a typical bunch crossing. To cope with the resultant increase in occupancy, bandwidth and radiation damage, the ATLAS Inner Detector will be replaced by an all-silicon system, the Inner Tracker (ITk). The ITk consists of a silicon pixel and a strip detector and exploits the concept of modularity. Prototyping and testing of various strip detector components has been carried out. This paper presents the developments and results obtained with reduced-size structures equivalent to those foreseen to be used in the forward region of the silicon strip detector. Referred to as petalets, these structures are built around a composite sandwich with embedded cooling pipes and electrical tapes for routing the signals and power. Detector modules built using electronic flex boards and silicon strip sensors are glued on both the front and back side surfaces of the carbon structure. Details are given on the assembly, testing and evaluation of several petalets. Measurement results of both mechanical and electrical quantities are shown. Moreover, an outlook is given for improved prototyping plans for large structures.Comment: 22 pages for submission for Journal of Instrumentatio