Recasting Economics as if the Climate and Global Ecology Really Mattered

Peer reviewedPublisher PD

Effects of organic matter input on soil microbial properties and crop yields in conventional and organic cropping systems

Unlike conventional cropping systems, which are characterised by targeted short-term fertility management, organic farming systems depend on long-term increase in soil fertility and promotion of soil biodiversity. This study sought to investigate long-term effects of organic matter inputs on various cropping systems in a 10-year-old experiment. Results show that in the long-term high C and N inputs enhance microbial activity. Microbial biomass N and the potential nitrification rate were higher in cropping systems based on green manure than in those reliant on inputs from animal manure and mineral fertilizer. Soil microbiological properties were affected by the individual crops in the rotation. The high microbial activity with increased organic matter inputs did not transform to enhanced crop productivity

L'objet et ses contextes

Over the past few decades, numerous theoretical works have revealed the abundance and diversity of meanings and qualities possessed by artifacts. Besides their shape and composition, artifacts have functions. They are the bearers of symbolic values and representations. Thus, the study of an artifact reveals a technology, an environment, a skill, a need, a taste and an aesthetic sense. This article looks at how to integrate the various facets of the artifact. It attempts to place it in an overall conceptual framework in which a practical and structured reading of the artifact from a transdisciplinary perspective becomes possible. It compares the different ways in which a conservator and a researcher examine an artifact and describes possible ways of establishing common ground. The researchers at the Centre d'études sur la langue, les arts et les traditions populaires des francophones en Amérique du Nord (CELAT) have thus tried to describe, in simple language that all scientists will understand, how to read the artifact, how to use it as an aid to reading and how to make it speak. Résumé Depuis quelques décennies, de nombreux travaux théoriques ont révélé la richesse et la diversité des sens et des qualités de l'objet. Par-delà leur forme et leur matière, les objets ont une fonction et des usages. Ils sont porteurs de valeurs symboliques et de représentations. Ainsi, l'étude de l'objet est révélatrice d'une technologie, d'un environnement, d'une compétence, d'un besoin, d'un goût, d'une esthétique. Cet article explore une façon d'intégrer ces différentes facettes de l'objet. Il tente de le situer dans un cadre conceptuel global pouvant déboucher sur des grilles pratiques de lecture dans une perspective transdiscipli-naire. Il compare les processus d'interrogation de l'objet par le conservateur et le chercheur et définit un lieu et des modalités de rencontre possibles. Les chercheurs du CELAT (Centre d'études sur la langue, les arts et les traditions populaires des francophones en Amérique du Nord) ont ainsi tenté de préciser en un langage simple qui pourrait être commun à tous les intervenants scientifiques une façon de lire l'objet, de lire par l'objet et de le faire parler

In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development

Acknowledgments: The authors would like to acknowledge the funding support for this work from Scottish Enterprise [VNAR_001(2012)] and the Biotechnology and Biological Sciences Research Council (BB/K010905/1).Peer reviewedPublisher PD

A combined microfinance and training intervention can reduce HIV risk behaviour in young female participants.

OBJECTIVE: To assess effects of a combined microfinance and training intervention on HIV risk behavior among young female participants in rural South Africa. DESIGN: : Secondary analysis of quantitative and qualitative data from a cluster randomized trial, the Intervention with Microfinance for AIDS and Gender Equity study. METHODS: Eight villages were pair-matched and randomly allocated to receive the intervention. At baseline and after 2 years, HIV risk behavior was assessed among female participants aged 14-35 years. Their responses were compared with women of the same age and poverty group from control villages. Intervention effects were calculated using adjusted risk ratios employing village level summaries. Qualitative data collected during the study explored participants' responses to the intervention including HIV risk behavior. RESULTS: After 2 years of follow-up, when compared with controls, young participants had higher levels of HIV-related communication (adjusted risk ratio 1.46, 95% confidence interval 1.01-2.12), were more likely to have accessed voluntary counseling and testing (adjusted risk ratio 1.64, 95% confidence interval 1.06-2.56), and less likely to have had unprotected sex at last intercourse with a nonspousal partner (adjusted risk ratio 0.76, 95% confidence interval 0.60-0.96). Qualitative data suggest a greater acceptance of intrahousehold communication about HIV and sexuality. Although women noted challenges associated with acceptance of condoms by men, increased confidence and skills associated with participation in the intervention supported their introduction in sexual relationships. CONCLUSIONS: In addition to impacts on economic well being, women's empowerment and intimate partner violence, interventions addressing the economic and social vulnerability of women may contribute to reductions in HIV risk behavior

On the spectroastrometric separation of binary point-source fluxes

Spectroastrometry is a technique which has the potential to resolve flux distributions on scales of milliarcseconds. In this study, we examine the application of spectroastrometry to binary point sources which are spatially unresolved due to the observational point spread function convolution. The technique uses measurements with sub-pixel accuracy of the position centroid of high signal-to-noise long-slit spectrum observations. With the objects in the binary contributing fractionally more or less at different wavelengths (particularly across spectral lines), the variation of the position centroid with wavelength provides some information on the spatial distribution of the flux. We examine the width of the flux distribution in the spatial direction, and present its relation to the ratio of the fluxes of the two components of the binary. Measurement of three observables (total flux, position centroid and flux distribution width) at each wavelength allows a unique separation of the total flux into its component parts even though the angular separation of the binary is smaller than the observations' point-spread function. This is because we have three relevant observables for three unknowns (the two fluxes, and the angular separation of the binary), which therefore generates a closed problem. This is a wholly different technique than conventional deconvolution methods, which produce information on angular sizes of the sampling scale. Spectroastrometry can produce information on smaller scales than conventional deconvolution, and is successful in separating fluxes in a binary object with a separation of less than one pixel. We present an analysis of the errors involved in making binary object spectroastrometric measurements and the separation method, and highlight necessary observing methodology.Comment: 11 pages, 8 figures, accepted for publication in Astronomy and Astrophysic

Novel, Anti-hTNF-α Variable New Antigen Receptor Formats with Enhanced Neutralising Potency and Multifunctionality, Generated for Therapeutic Development

ACKNOWLEDGMENTS The authors wish to acknowledge the funding support for this work from MSD/Scottish Universities Life Sciences Alliance (SULSA), Scottish Enterprise, the Biotechnology and Biological Sciences Research Council (BBSRC), and the University of Aberdeen. FUNDING Grateful for support from Biotechnology and Biological Sciences Research Council (BB/K010905/1), Scottish Enterprise [VNAR_001 (2012)], Scottish Universities Life Sciences Alliance/ MSD (MSD01_A_Porter-Teismann), and the College of Life Sciences and Medicine, University of Aberdeen (Fee bursary to OU).Peer reviewedPublisher PD

National Institute of Neurological Disorders and Stroke (NINDS): Advances in understanding and treating neuropathy, 24–25 October 2006; Bethesda, Maryland

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75348/1/j.1529-8027.2008.00154.x.pd

Detection of efflux pump activity among clinical isolates of Staphylococcus and Micrococcus species

Purpose: To detect efflux pump activity (EPA) and screening a suspected efflux pump inhibitor (EPI) [1- (3-(trifluoromethyl)benzyl]-piperazine (TFMBP)], which could help in reducing multi-drug resistance (MDR).Methods: Eighteen isolates, viz, 14 S. aureus, 2 S. lentus, 1 S. xylosus and 1 Micrococcus species from various hospital infections of admitted patients were screened for antibiotics susceptibility to 11 classes of antibiotics including oxacillin and β-lactamase production. Efflux pump activity (EPA) was determined by minimum inhibitory concentration (MIC) technique in the presence and absence of TFMBP, the isolates were also screened for MDR genes.Results: All the isolates were resistant to ampicillin (10 μg) and penicillin (10 μg), but sensitive to bacitracin (10 μg). Majority of the isolates were MDR 12/18 (66.7 %), 10 (55.6 %) were inducible β- lactamase producers and 3 (16.7 %) were intrinsic β-lactamase producers. Seven (38.9 %) were resistant to oxacillin and also produced carbapenemase enzyme. Eight (66.7 %) of the 12 MDR isolates gave evidence of EPA with TFMBP. However, no MDR genes were detected.Conclusion: Staphylococcus and Micrococcus species exhibit EPA in antibiotic resistance while a suitable EPI such as TFMBP when combined with specific antibiotics could help combat this menace.Keywords: [1-(3-(Trifluoromethyl)benzyl]-piperazine, Efflux pump activity, Oxacillin resistant S. aureus, Multidrug resistant, Carbapenemas