New insights into the biomechanics of Legg-Calvé-Perthes’ disease: The role of epiphyseal skeletal immaturity in vascular obstruction

ObjectivesLegg–Calvé–Perthes’ disease (LCP) is an idiopathic osteonecrosis of the femoral head that is most common in children between four and eight years old. The factors that lead to the onset of LCP are still unclear; however, it is believed that interruption of the blood supply to the developing epiphysis is an important factor in the development of the condition.MethodsFinite element analysis modelling of the blood supply to the juvenile epiphysis was investigated to understand under which circumstances the blood vessels supplying the femoral epiphysis could become obstructed. The identification of these conditions is likely to be important in understanding the biomechanics of LCP.ResultsThe results support the hypothesis that vascular obstruction to the epiphysis may arise when there is delayed ossification and when articular cartilage has reduced stiffness under compression.ConclusionThe findings support the theory of vascular occlusion as being important in the pathophysiology of Perthes disease

Identificação e aspectos bioecológicos do gavião-caramujeiro (Rosthramus sociabilis) visando sua utilização como indicador de sustentabilidade na região costeira do Sul do Rio Grande do Sul.

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Fluxo gênico em feijoeiro comum: ocorrência e possíveis conseqüências.

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Sistemas de criação de capivaras.

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Desempenho reprodutivo da capivara (Hydrochaeris hydrochaeris) em criação semi-intensiva na região Costeira Sul do Rio Grande do Sul.

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