A kinetic model and simulation of starch saccharification and simultaneous ethanol fermentation by amyloglucosidase and Zymomonas mobilis

A mathematical model is described for the simultaneous saccharification and ethanol fermentation (SSF) of sago starch using amyloglucosidase (AMG) and Zymomonas mobilis. By introducing the degree of polymerization (DP) of oligosaccharides produced from sago starch treated with α -amylase, a series of Michaelis-Menten equations were obtained. After determining kinetic parameters from the results of simple experiments carried out at various substrate and enzyme concentrations and from the subsite mapping theory, this model was adapted to simulate the SSF process. The results of simulation for SSF are in good agreement with experimental results.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/47811/1/449_2004_Article_BF00369488.pd

An interdisciplinary approach to characterize peanut-allergic patients - first data from the FOOD@ consortium

BACKGROUND: Peanut allergy is a frequent cause of food allergy and potentially life-threatening. Within this interdisciplinary research approach, we aim to unravel the complex mechanisms of peanut allergy. As a first step were applied in an exploratory manner the analysis of peanut allergic versus non-allergic controls. METHODS: Biosamples were studied regarding DNA methylation signatures, gut microbiome, adaptive and innate immune cell populations, soluble signaling molecules and allergen-reactive antibody specificities. We applied a scalable systems medicine computational workflow to the assembled data. RESULTS: We identified combined cellular and soluble biomarker signatures that stratify donors into peanut-allergic and non-allergic with high specificity. DNA methylation profiling revealed various genes of interest and stool microbiota differences in bacteria abundances. CONCLUSION: By extending our findings to a larger set of patients (e.g., children vs. adults), we will establish predictors for food allergy and tolerance and translate these as for example, indicators for interventional studies

Laboratory equipment to optimise integrated communication systems for military helicopters

What has been presented in the paper is a research/testing tool used in the Air F orce Institute of Technology (Instytut Techniczny Wojsk Lotniczych - ITWL) to build, actuate, test, and optimise integrated communication systems as far as both a set of devices the system is composed of and the applied software are concerned. Particular attention has been paid to the so-called integration station (built under the Mi-8, Mi-17, Mi-24 upgrade project), i.e. the laboratory equipment to optimise and unify communication systems integrated on the basis of digital data buses (following the MIL-1553B standard, among other ones). Such equipment has allowed ITWL to integrate new communication devices/systems while upgrading the W-3PL helicopter. Some selected tasks performed with this equipment engagedhave been discussed. Also, problems arising while actuating and testing the developed software to integrate communication devices/systems (including digitally controlled radio stations of the RRC, HARRIS, and MR6000 types, communication control panels of the PSL-1 type and multi-function displays of the MW-l type) have been given consideration in the scope of the software functionality and reliability. Presented are also additional monitoring and measuring systems used to test this software, just to mention the M230 rugged laptop computer used to diagnose the system and prepare plans of the radio communication

Radioelectronic and thermovisual support in display systems to aid in searching for sea-going ships from search & rescue helicopters

This paper presents the basic principles of SAR (Search and Rescue) and CSAR (Combat Search and Rescue) missions, with the SAR support systems installed on-board Polish and German military helicopters presented in more detail. Mi8/17 and W3PL “Głuszec” helicopters with an integrated avionics system (designed and constructed in the Air Force Institute of Technology) used in combination with an on-board weaponry system are designed to undertake CSAR missions. A TOPLITE observation-targeting head (with TV and FLIR thermal cameras, for day and night operation respectively) and a RSC125G on-board radio direction finder were used to search for survivors. The weaponry system of the W3PL “Głuszec” helicopter is involved in supporting CSAR search-rescue tasks, e.g. functions of targeting with the use of a Head-Up Display (HUD) (through the integrated ballistic computer) and imaging with the use of a TOPLITE head monitor