Eat, Sleep, Console for Neonatal Abstinence Syndrome Babies

Neonatal Abstinence Syndrome (NAS) is a complex disorder that manifests with neurologic, gastrointestinal, and musculoskeletal disturbances and is most often associated with opioid withdrawal. In the US, 6 out of 1,000 babies are born to mothers who used opioids during their pregnancy. These babies go on to develop NAS. Androscoggin County, where Central Maine Medical Center is located, has an even higher rate of babies with NAS: 100 out of 1,000. Most institutions use the Finnegan Neonatal Abstinence Scoring System (FNASS) to guide pharmacologic treatment. This system assigns a score based on 21 clinical signs of withdrawal with a score ≥8 indicating a need for pharmacologic treatment. This system has never been validated nor has its score cutoffs been tested which may lead to over or under treatment of babies experiencing NAS. Eat, Sleep, Console is a novel approach which has shown to decrease average length of stay, pharmacologic treatment, and healthcare costs.https://scholarworks.uvm.edu/fmclerk/1503/thumbnail.jp

Sacrifice and Emotional Communities in Early Modern Literature

The early modern period in England was a time of intense political, religious, and cultural upheaval. Between the Protestant Reformation and urbanization, England experienced significant ideological changes as well as the growing pains of overpopulation and plague in its major cities. The literature of the time illustrates the emotional complexity that many of the authors and citizens experienced firsthand as a result of the tumult in England. This thesis focuses specifically on the period during the reigns of Queen Elizabeth I and James I, using the works of Sir Philip Sidney and John Donne as structural buoys for the paper, and a mid-section focused on Shakespeare in order to identify three examples of literary sacrifice that comment on and critique the writers’ own experiences with the social, political, and religious landscape of early modern England. The theme of sacrifice became a vehicle for the early modern writers’ nuanced critiques of their own historical contexts. At the very heart of sacrifice is surrender: the authors were being asked to give something up in order to maintain harmony within their own communities and their literature comments on these sacrifices

Reducing Stress, Anxiety, and Depression for NICU Parents

This project aims to appraise evidence of the effectiveness of various practices on reducing stress, anxiety, and depression among parents of infants in the neonatal intensive care unit (NICU). The project contains six research articles from both national and international journals. Study designs include one meta-analysis, one randomized controlled trial, one small scale randomized controlled trial, one prospective phase lag cohort study, on pretest-posttest study, and one mixed-methods pretest-posttest study. Recommendations for effective interventions were based on best evidence discovered through quality appraisal and study outcomes. All interventions, except for educational programs and Kangaroo Care, resulted in a statistically significant reduction of either stress, anxiety, and/ or depression. Family centered care and mindfulness-based intervention reduced all barriers of interest. There is strong and high-quality evidence for the effect of Cognitive Behavioral Therapy on depression, moderate evidence for the effect of activity-based group therapy on anxiety, and promising evidence for the effect of HUG Your Baby on stress

End of One Way

Describes the role of three South Minneapolis community-based organizations. Demonstrates how the organizations form partnerships and share leadership with their communities. Explores a set of themes derived from each example of community engagement

Nutrition Knowledge Assessment of Lund Family Center Residents

Introduction. Staff at the Lund Family Center report that there may be knowledge deficits, with regards to nutrition, among the Center’s residents—primarily pregnant/ parenting women with substance abuse and mental health issues. Before considering intervention options, we wanted to identify the specifics of the residents’ knowledge gaps. Methods. We administered paper versions of a revised General Nutrition Knowledge Questionnaire (GNKQ-R) Section 2 to 21 Lund residents to explore nutri- tion knowledge as compared to groups more representative of the general population. The GNKQ-R Section 2 is an externally validated, efficacious tool that specifically as- sesses knowledge of food groups and nutrients. Demographic data and free-response personal assessments of health were also collected. Results. The study population scored significantly lower than a UK population (p=0.002) previously analyzed using the questionnaire, however, the Lund residents scored significantly higher than a CA population (p=0.0001). There were statistically insignificant positive relationships between age, education level, and self-reported health status, in addition to slightly lower performances among those with “Single” relationship status. Conclusions. Though demonstrated by a small, homogenous population, the statistically significant nutrition knowledge deficit of the Lund Family Center residents, relative to the referenced UK study, warranted intervention. A brief nutrition curriculum composed of 16 focused modules was developed for future administration. The modules were oriented towards family nutrition, with content including such topics as breastfeeding advice, including children in meal-making, and macronutrient basics. These modules will be delivered to Lund residents in 2018.https://scholarworks.uvm.edu/comphp_gallery/1261/thumbnail.jp

Children\u27s Judgments of Age

Age judgments of human figures by children, ranging in age from 3 through 9 years, were investigated. The stimuli consisted of 4 different male figures drawn according to typical physical characteristics of the middle-aged adult, adolescent child, and infant. The figures were reproduced in 2 sizes and were matched in all possible pairings. Ss\u27 accuracy in age judgments increased steadily over the 7 age levels. The errors of young Ss were primarily due to a figural-size response set. Older Ss made increasing use of other physical features in making their judgments. Implications of these findings were discussed with references to the theoretical framework of Piaget

Comprehensive Genetic Testing Identifies Targetable Genomic Alterations in Most Patients with Non-Small Cell Lung Cancer, Specifically Adenocarcinoma, Single Institute Investigation

This study reviews extensive genetic analysis in advanced non-small cell lung cancer (NSCLC) patients in order to: describe how targetable mutation genes interrelate with the genes identified as variants of unknown significance; assess the percentage of patients with a potentially targetable genetic alterations; evaluate the percentage of patients who had concurrent alterations, previously considered to be mutually exclusive; and characterize the molecular subset of KRAS. Thoracic Oncology Research Program Databases at the University of Chicago provided patient demographics, pathology, and results of genetic testing. 364 patients including 289 adenocarcinoma underwent genotype testing by various platforms such as FoundationOne, Caris Molecular Intelligence, and Response Genetics Inc. For the entire adenocarcinoma cohort, 25% of patients were African Americans; 90% of KRAS mutations were detected in smokers, including current and former smokers; 46% of EGFR and 61% of ALK alterations were detected in never smokers. 99.4% of patients, whose samples were analyzed by next-generation sequencing (NGS), had genetic alterations identified with an average of 10.8 alterations/tumor throughout different tumor subtypes. However, mutations were not mutually exclusive. NGS in this study identified potentially targetable genetic alterations in the majority of patients tested, detected concurrent alterations and provided information on variants of unknown significance at this time but potentially targetable in the future

The Grizzly, February 22, 2001

Student E-mail Service Altered After Spate of Abuse • National Sorority to Open UC Chapter • New Curriculum to Emphasize Diversity, Fine Arts • Ursinus Students Show Political Spirit in Protest • Threat of Serial Bomber Creeps Closer to Collegeville • SPINT Week Informs Students of Alternative Housing Options • Ursinus Students React to Court\u27s Ruling that Napster Must Shut Down • Opinions: Welcome to the Board; Hazing Still Prevalent During New Member Education ; Should Drugs be Legalized for Civilian Use? • Bears Clinch top Seed in Playoffs with Thrilling Overtime win • Third Place Finish for Wrestling Squad at CCC Match • Druckenmiller, Augelli, Jaskelewicz Lead Bears at Swimming Championships • Gymnastics Team Beats Springfield, Takes Fourth at Invitational • UC Track Team Looks Ahead to Conference Champs • Guisto, Hussey Lead Women to win in Season Finalehttps://digitalcommons.ursinus.edu/grizzlynews/1484/thumbnail.jp