409 research outputs found

    Combined anterior segment OCT and wavefront-based autorefractor using a shared beam

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    We have combined an anterior segment (AS) optical coherence tomography (OCT) system and a wavefront-based aberrometer with an approach that senses ocular wavefront aberrations using the OCT beam. Temporal interlacing of the OCT and aberrometer channels allows for OCT images and refractive error measurements to be acquired continuously and in real-time. The system measures refractive error with accuracy and precision comparable to that of clinical autorefractors. The proposed approach provides a compact modular design that is suitable for integrating OCT and wavefront-based autorefraction within the optical head of the ophthalmic surgical microscope for guiding cataract surgery or table-top devices for simultaneous autorefraction and ocular biometry

    Optical Power of the Isolated Human Crystalline Lens

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    PURPOSE. To characterize the age dependence of isolated human crystalline lens power and quantify the contributions of the lens surfaces and refractive index gradient. METHODS. Experiments were performed on 100 eyes of 73 donors (average 2.8 Ϯ 1.6 days postmortem) with an age range of 6 to 94 years. Lens power was measured with a modified commercial lensmeter or with an optical system based on the Scheiner principle. The radius of curvature and asphericity of the isolated lens surfaces were measured by shadow photography. For each lens, the contributions of the surfaces and the refractive index gradient to the measured lens power were calculated by using optical ray-tracing software. The age dependency of these refractive powers was assessed. RESULTS. The total refractive power and surface refractive power both showed a biphasic age dependency. The total power decreased at a rate of Ϫ0.41 D/y between ages 6 and 58.1, and increased at a rate of 0.33D/y between ages 58.1 and 82. The surface contribution decreased at a rate of Ϫ0.13 D/y between ages 6 and 55.2 and increased at a rate of 0.04 D/y between ages 55.2 and 94. The relative contribution of the surfaces increased by 0.17% per year. The equivalent refractive index also showed a biphasic age dependency with a decrease at a rate of Ϫ3.9 ϫ 10 Ϫ4 per year from ages 6 to 60.4 followed by a plateau. CONCLUSIONS. The lens power decreases with age, due mainly to a decrease in the contribution of the gradient. The use of a constant equivalent refractive index value to calculate lens power with the lens maker formula will underestimate the power of young lenses and overestimate the power of older lenses. (Invest Ophthalmol Vis Sci. 2008;49:2541-2548) DOI: 10.1167/iovs.07-1385 T he optical power of the crystalline lens is determined by the surface curvatures, the refractive index differences at the aqueous lens and lens vitreous interfaces, and the refractive index gradient distribution within the lens. 1 Studying the optical properties of the lens (i.e., optical power, refractive index distribution, and the surface refractive contributions) in vivo is difficult because of the position of the lens behind the cornea and pupil, as well as the distortions of the posterior lens surface caused by the lens refractive index gradient. Two approaches have been used to measure the lens power in vivo. In the first approach the curvatures of the lens surface and lens thickness are measured by phakometry and ultrasonic or optical biometry. The lens power is then calculated assuming an equivalent uniform refractive index (typically, ϳ1.42). 2,3 In the second approach, the lens power is calculated from measurements of axial eye length, anterior chamber depth, corneal power, and refractive state of the eye. These parameters are input into an eye model to calculate the power required for the lens to produce an optical system that matches the measurements. 3-6 Both techniques derive the lens power from measurements of other ocular parameters. Even though recent studies have cross-validated in vivo lens biometry techniques 9 -15 A comparison of in vivo -21 The isolated lens power has been shown to decrease with age

    Focusing Light Dimmer for the Zeiss Fundus Camera

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    A plug-in device allowed full, fingertip control of the observation light of the Zeiss fundus camera
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