903 research outputs found
Red and orange laser operation of Pr:KYF4 pumped by a Nd:YAG/LBO laser at 469.1nm and a InGaN laser diode at 444nm
We report the basic luminescence properties and the continuous-wave (CW) laser operation of a Pr3+-doped KYF4 single crystal in the Red and Orange spectral regions by using a new pumping scheme. The pump source is an especially developed, compact, slightly tunable and intra-cavity frequency-doubled diode-pumped Nd:YAG laser delivering a CW output power up to about 1.4 W around 469.1 nm. At this pump wavelength, red and orange laser emissions are obtained at about 642.3 and 605.5 nm, with maximum output powers of 11.3 and 1 mW and associated slope efficiencies of 9.3% and 3.4%, with respect to absorbed pump powers, respectively. For comparison, the Pr:KYF4 crystal is also pumped by a InGaN blue laser diode operating around 444 nm. In this case, the same red and orange lasers are obtained, but with maximum output powers of 7.8 and 2 mW and the associated slope efficiencies of 7 and 5.8%, respectively. Wavelength tuning for the two lasers is demonstrated by slightly tilting the crystal. Orange laser operation and laser wavelength tuning are reported for the first time
Management of the hospitalized transplant patient.
Significant hyperglycemia is commonly observed immediately after solid organ and bone marrow transplant as well as with subsequent hospitalizations. Surgery and procedures are well known to cause pain and stress leading to secretion of cytokines and other hormones known to aggravate insulin action. Immunosuppression required for transplant and preexisting risk are also major factors. Glucose control improves outcomes for all hospitalized patients, including transplant patients, but is often more challenging to achieve because of frequent and sometimes unpredictable changes in immunosuppression doses, renal function, and nutrition. As a result, risk of hypoglycemia can be greater in this patient group when trying to achieve glucose control goals for hospitalized patients. Key to successful management of hyperglycemia is regular communication between the members of the care team as well as anticipating and rapidly implementing a new treatment paradigm in response to changes in immunosuppression, nutrition, renal function, or evidence of changing insulin resistance
Extending Phenomenological Crystal-Field Methods to Point-Group Symmetry: Characterization of the Optically-Excited Hyperfine Structure of Er:YSiO
We show that crystal-field calculations for point-group symmetry are
possible, and that such calculations can be performed with sufficient accuracy
to have substantial utility for rare-earth based quantum information
applications. In particular, we perform crystal-field fitting for a
C-symmetry site in Er:YSiO. The calculation
simultaneously includes site-selective spectroscopic data up to 20,000
cm, rotational Zeeman data, and ground- and excited-state hyperfine
structure determined from high-resolution Raman-heterodyne spectroscopy on the
1.5 m telecom transition. We achieve an agreement of better than 50 MHz
for assigned hyperfine transitions. The success of this analysis opens the
possibility of systematically evaluating the coherence properties, as well as
transition energies and intensities, of any rare-earth ion doped into
YSiO .Comment: 6 pages, plus 5 pages in supplementary information, 4 figures tota
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for sarcomatosis from uterine adenosarcoma
Uterine adenosarcoma has poor prognosis and management of this disease is controversial. We describe a case of sarcomatosis secondary to recurrent uterine adenosarcoma who underwent cytoreductive surgery (CS) and hyperthermic intraoperative peritoneal chemotherapy (HIPEC). A 52 year-old female presented with perimenopausal menometrorrhagia. She underwent laparoscopic hysterectomy and bilateral salpingo-oopherectomy with pathology showing uterine adenosarcoma. She developed a pelvic recurrence 2 years later. A pelvic exenteration was then performed and within 8 months, she recurred. CS/HIPEC with Cisplatin was performed. Six weeks post-operatively, the patient was found to have recurrence again. This case describes the use of CS/HIPEC as a treatment modality for uterine adenosarcoma with sarcomatosis. Despite CS and HIPEC, the patient developed an aggressive recurrence within six weeks of her surgery date. We recommend a multidisciplinary approach to this disease with the recognition that CS/HIPEC may offer little benefit as a salvage therapy based on this case
Influence of Polyphenol Levels on the Perception of Aroma in Vitis vinifera cv. Malbec wine
The aim of this study was to explore the effect of two ranges of polyphenols naturally present in Malbec wine,high concentrations (4.5-7.2 g/L) and low (1.4-3.2 g/L), on the perception of aroma. Samples with a maximumethanol level of 13.5% were taken from the fermentation tanks before the clarification and filtration process. AQuantitative Descriptive Analysis of wines was assessed by ten trained assessors, and HS-SPME-GC-MS andphysicochemical analyses were performed. The intensities of fruity (P < 0.01), citrus (P < 0.01), strawberry (P< 0.05), cooked fruit (P < 0.01) and floral (P < 0.01) aromas decreased when the level of polyphenols increased.Neither volatile compounds nor physicochemical analyses were significant in the two groups of wines
High precision Monte Carlo study of the 3D XY-universality class
We present a Monte Carlo study of the two-component model on the
simple cubic lattice in three dimensions. By suitable tuning of the coupling
constant we eliminate leading order corrections to scaling. High
statistics simulations using finite size scaling techniques yield
and , where the statistical and
systematical errors are given in the first and second bracket, respectively.
These results are more precise than any previous theoretical estimate of the
critical exponents for the 3D XY universality class.Comment: 13 page
Single-Molecule-Sensitive FRET in Freely-Diffusing Attoliter Droplets
Fluorescence resonance energy transfer (FRET) from individual, dye-labeled
RNA molecules confined in freely-diffusing attoliter-volume aqueous droplets is
carefully compared to FRET from unconfined RNA in solution. The use of
freely-diffusing droplets is a remarkably simple and high-throughput technique
that facilitates a substantial increase in signal-to-noise for
single-molecular-pair FRET measurements. We show that there can be dramatic
differences between FRET in solution and in droplets, which we attribute
primarily to an altered pH in the confining environment. We also demonstrate
that a sufficient concentration of a non-ionic surfactant mitigates this effect
and restores FRET to its neutral-pH solution value. At low surfactant levels,
even accounting for pH, we observe differences between the distribution of FRET
values in solution and in droplets which remain unexplained. Our results will
facilitate the use of nanoemulsion droplets as attoliter volume reactors for
use in biophysical and biochemical assays, and also in applications such as
protein crystallization or nanoparticle synthesis, where careful attention to
the pH of the confined phase is required.Comment: Twenty-three pages, 3 figures, one table, plus supporting information
with additional figures and table
Influence of different PEEP levels and tidal volumes on the regional nonaerated tissue: experimental study
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