2005 PRETEXT: a revised staging system for primary malignant liver tumours of childhood developed by the SIOPEL group

Over the last 15 years, various oncology groups throughout the world have used the PRETEXT system for staging malignant primary liver tumours of childhood. This paper, written by members of the radiology and surgery committees of the International Childhood Liver Tumor Strategy Group (SIOPEL), presents various clarifications and revisions to the original PRETEXT system

All-sky Medium Energy Gamma-ray Observatory: Exploring the Extreme Multimessenger Universe

The All-sky Medium Energy Gamma-ray Observatory (AMEGO) is a probe class mission concept that will provide essential contributions to multimessenger astrophysics in the late 2020s and beyond. AMEGO combines high sensitivity in the 200 keV to 10 GeV energy range with a wide field of view, good spectral resolution, and polarization sensitivity. Therefore, AMEGO is key in the study of multimessenger astrophysical objects that have unique signatures in the gamma-ray regime, such as neutron star mergers, supernovae, and flaring active galactic nuclei. The order-of-magnitude improvement compared to previous MeV missions also enables discoveries of a wide range of phenomena whose energy output peaks in the relatively unexplored medium-energy gamma-ray band

Good Samaritan liver donor in pediatric transplantation.

We report a case of anonymous liver transplantation from adult to child

Historical review and perspectives in pediatric transplantation

Purpose of review Recent progress in organ transplantation in children is illustrated by analysis of the most informative papers published during 2005-2006. Recent findings The review focuses on immunosuppression, steroid withdrawal or avoidance, living-related transplantation, long-term survival, drug-related nephrotoxicity, growth, and quality of life in solid organ transplantation. Summary Research on better, more selective, and safer immunosuppression must be pursued as well as the search for surrogate markers of tolerance. Long-term analysis is needed of quality of life beyond 10 - 15 years after transplantation