12,706 research outputs found
Alternative determinism principle for topological analysis of chaos
The topological analysis of chaos based on a knot-theoretic characterization
of unstable periodic orbits has proved a powerful method, however knot theory
can only be applied to three-dimensional systems. Still, the core principles
upon which this approach is built, determinism and continuity, apply in any
dimension. We propose an alternative framework in which these principles are
enforced on triangulated surfaces rather than curves and show that in dimension
three our approach numerically predicts the correct topological entropies for
periodic orbits of the horseshoe map.Comment: Accepted for publication as Rapid Communication in Physical Review
Auctions as a vehicle to reduce airport delays and achieve value capture
Congestion at airports imposes large costs on airlines and their passengers. A key reason for congestion is that an airline schedules its flights without regard to the costs imposed on other airlines and their passengers. As a result, during some time intervals, airlines schedule more flights to and from an airport than that airport can accommodate and flights are delayed. This paper explores how a specific market-based proposal by the Federal Aviation Administration (FAA), which includes the use of auctions to determine the right to arrive or depart in a specific time interval at airports in the New York City area, might be used as part of a strategy to mitigate delays and congestion. By explaining the underlying economic theory and key arguments with minimal technical jargon, the paper allows those with little formal training in economics to understand the fundamental issues associated with the FAA's controversial proposal. Moreover, the basics of the proposed auction process, known as a combinatorial auction, and value capture are also explained.Airlines ; Airports
Ultracold Atoms as a Target: Absolute Scattering Cross-Section Measurements
We report on a new experimental platform for the measurement of absolute
scattering cross-sections. The target atoms are trapped in an optical dipole
trap and are exposed to an incident particle beam. The exponential decay of the
atom number directly yields the absolute total scattering cross-section. The
technique can be applied to any atomic or molecular species that can be
prepared in an optical dipole trap and provides a large variety of possible
scattering scenarios
Patient-specific 3D Printed Liver Models for Pre-operative Planning and Improved Patient Adherence
Project Background: 3D anatomical relationships in the liver are not always visually accessible for surgeons performing resections even with advanced imaging options. Firm understanding of these relationships is essential for timely procedures, which can improve patient outcomes and lower hospital expenses. Patient-specific 3D modeling has existed for some time, though it is costly. New cost-effective techniques have surfaced which may yield opportunities for more effective preoperative planning in liver surgery and improved patient adherence.
Methods: Digital patient-specific 3D reconstruction of a liver was completed by interpolating data from MRI scans using 3D Slicer, a segmenting program. The liver model was processed and 3D printed as a shell to be used as a mold. The liver shell, associated vasculature, and tumor were printed using polylactic acid (PLA) filament on an Ultimaker S5 3D printer. Transparent silicone was used as a cast, giving the model a solid form yet still allowing examination of the inside contents.
Results: One completed liver model was used in pre-surgical consultation of a patient with hepatocellular carcinoma undergoing liver resection and during the surgical procedure as a guide for the surgical team. A follow-up survey concerning qualitative aspects of the model administered to the surgical team suggested high accuracy of the model compared to the anatomy observed during the procedure.
Conclusion: Cost-effective techniques in producing patient specific 3D anatomical models appears not only feasible, but highly effective in improving communication between the surgical team during the procedure and also between the surgeon and the patient during pre-surgical consultation. Future research may be conducted concerning the model’s visual clarity as well as impact on patient adherence post-op
Exact Results for the Kuramoto Model with a Bimodal Frequency Distribution
We analyze a large system of globally coupled phase oscillators whose natural
frequencies are bimodally distributed. The dynamics of this system has been the
subject of long-standing interest. In 1984 Kuramoto proposed several
conjectures about its behavior; ten years later, Crawford obtained the first
analytical results by means of a local center manifold calculation.
Nevertheless, many questions have remained open, especially about the
possibility of global bifurcations. Here we derive the system's complete
stability diagram for the special case where the bimodal distribution consists
of two equally weighted Lorentzians. Using an ansatz recently discovered by Ott
and Antonsen, we show that in this case the infinite-dimensional problem
reduces exactly to a flow in four dimensions. Depending on the parameters and
initial conditions, the long-term dynamics evolves to one of three states:
incoherence, where all the oscillators are desynchronized; partial synchrony,
where a macroscopic group of phase-locked oscillators coexists with a sea of
desynchronized ones; and a standing wave state, where two counter-rotating
groups of phase-locked oscillators emerge. Analytical results are presented for
the bifurcation boundaries between these states. Similar results are also
obtained for the case in which the bimodal distribution is given by the sum of
two Gaussians.Comment: 28 pages, 7 figures; submitted to Phys. Rev. E Added comment
The Role of Collective Neutrino Flavor Oscillations in Core-Collapse Supernova Shock Revival
We explore the effects of collective neutrino flavor oscillations due to
neutrino-neutrino interactions on the neutrino heating behind a stalled
core-collapse supernova shock. We carry out axisymmetric (2D)
radiation-hydrodynamic core-collapse supernova simulations, tracking the first
400 ms of the post-core-bounce evolution in 11.2 solar mass and 15 solar mass
progenitor stars. Using inputs from these 2D simulations, we perform neutrino
flavor oscillation calculations in multi-energy single-angle and multi-angle
single-energy approximations. Our results show that flavor conversions do not
set in until close to or outside the stalled shock, enhancing heating by not
more than a few percent in the most optimistic case. Consequently, we conclude
that the postbounce pre-explosion dynamics of standard core-collapse supernovae
remains unaffected by neutrino oscillations. Multi-angle effects in regions of
high electron density can further inhibit collective oscillations,
strengthening our conclusion.Comment: v2: Added multi-angle calculations. Conclusions unchanged. 16 pages,
7 figures. Accepted to Phys. Rev. D after revisions: 15 Sept 2011 (major), 24
Jan 2012 (minor
Cellular mRNAs access second ORFs using a novel amino acid sequence-dependent coupled translation termination-reinitiation mechanism
Polycistronic transcripts are considered rare in the human genome. Initiation of translation of internal ORFs of eukaryotic genes has been shown to use either leaky scanning or highly structured IRES regions to access initiation codons. Studies on mammalian viruses identified a mechanism of coupled translation termination-reinitiation that allows translation of an additional ORF. Here, the ribosome terminating translation of ORF-1 translocates upstream to reinitiate translation of ORF-2. We have devised an algorithm to identify mRNAs in the human transcriptome in which the major ORF-1 overlaps a second ORF capable of encoding a product of at least 50 aa in length. This identified 4368 transcripts representing 2214 genes. We investigated 24 transcripts, 22 of which were shown to express a protein from ORF-2 highlighting that 3' UTRs contain protein-coding potential more frequently than previously suspected. Five transcripts accessed ORF-2 using a process of coupled translation termination-reinitiation. Analysis of one transcript, encoding the CASQ2 protein, showed that the mechanism by which the coupling process of the cellular mRNAs was achieved was novel. This process was not directed by the mRNA sequence but required an aspartate-rich repeat region at the carboxyl terminus of the terminating ORF-1 protein. Introduction of wobble mutations for the aspartate codon had no effect, whereas replacing aspartate for glutamate repeats eliminated translational coupling. This is the first description of a coordinated expression of two proteins from cellular mRNAs using a coupled translation termination-reinitiation process and is the first example of such a process being determined at the amino acid level
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