Comparative Study of Neuronal Degenerative Potentials of Ethanolic Root Bark and Leaf Extracts of Rauwolfia Vomitoria on the Cerebellum of Adult Wistar Rats

Rauwolfia vomitoria has been used for centuries in India and Africa for treatment of a variety of disorders including snake bites and sting, insomnia and insanity. Neuronal degenerative potentials of ethanolic root bark and leaf extracts of Rauwolfia vomitoria on the cerebellum of adult wistar rats was investigated. Thirty wistar rats weighing between 170-240g were divided into six groups, each consisting of five rats. Groups A served as the normal control that received distilled water while group B served as the olive oil control that received 0.5mls of olive oil. Experimental groups C and D received 200mg/kg, 300mg/kg of ethanolic root bark extracts while groups E and F received 200mg/kg, 300mg/kg of the leaf extract orally respectively for seven days.  In this study, the treatment groups showed a dose-dependent degree of silver impregnation of the cell bodies and axons. The sections of the cerebellar cortex of the treated group C, D, E and F showed various degrees of neurodegenerative changes highlighted by the silver stain impregnation which was more intense in groups C and D that received 200mg/kg and 300mg/kg ethanolic root-bark than in the groups E and F that received 200mg/kg and 300mg/kg of ethanolic leaf extract. These changes may result in cerebellar dysfunction Keywords: Ethanolic extracts, Root-bark extract, Leaf extract, Rauwolfia vomitoria

Analytical solutions of the N-dimensional Schrödinger equation with modified screened Kratzer plus inversely quadratic Yukawa potential and thermodynamic properties of selected diatomic molecules

In this study, we presented approximate analytical solutions to the N-dimensional Schrödinger equation with the screened modified Kratzer plus inversely quadratic Yukawa potential (SMKIQYP) by adopting the Nikiforov-Uvarov method and using the Greene-Aldrich approximation scheme for the inverse square term. The obtained energy eigenvalues were used to investigate four diatomic molecules: Hydrogen (H2), Iodine (I2), Nitrogen monoxide (NO), and Carbon monoxide (CO). The numerical results of the energy spectrum for the NO and CO molecules based on some of the deduced potentials such as modified Kratzer and screened modified Kratzer potentials were also determined. Then, using the obtained partition function, we calculated the thermodynamic properties such as the mean energy, specific heat, entropy, and free energy of the aforementioned diatomic molecules. The partition function of the H2, CO, and I2 diatomic molecules was computed for various temperatures. The results show that the partition function of the three diatomic molecules increased with increasing temperature. To validate our results, the numerical results of the energy spectrum for a few recovered potentials were compared with the results available in the literature, and we observed that our results are in excellent agreement