6 research outputs found
Habitual miscarriage in women with a combination of autoimmune diseases of the thyroid gland and AFS
In world literature, published many works, the main object of study are women of reproductive age, including healthy women, women with recurrent pregnancy loss and infertile women undergoing assisted reproductive technologies. Most of these studies showed a significant Association between the presence tireoidnykh autoantibodies, infertility and an increased risk of miscarriage. Adequate levels of circulating blood levels of thyroid hormones is the subject of βEssentialsβ for the normal functioning of the reproductive system. This article examines the relationship of miscarriage with autoimmune thyroid diseases and circulation of antiphospholipid antibodies. This Association is not accidental. A possible mechanism for this relationship is the fact that the presence of antithyroid antibodies reflects a generalized activation of the immune system and enhances autoimmune process directed against fetoplacental system.Π ΠΌΠΈΡΠΎΠ²ΠΎΠΉ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΠ΅ ΠΎΠΏΡΠ±Π»ΠΈΠΊΠΎΠ²Π°Π½ΠΎ ΠΌΠ½ΠΎΠ³ΠΎ ΡΠ°Π±ΠΎΡ, ΠΎΡΠ½ΠΎΠ²Π½ΡΠΌ ΠΎΠ±ΡΠ΅ΠΊΡΠΎΠΌ ΠΈΠ·ΡΡΠ΅Π½ΠΈΡ ΠΊΠΎΡΠΎΡΡΡ
ΡΠ²Π»ΡΡΡΡΡ ΠΆΠ΅Π½ΡΠΈΠ½Ρ ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, Π²ΠΊΠ»ΡΡΠ°Ρ Π·Π΄ΠΎΡΠΎΠ²ΡΡ
ΠΆΠ΅Π½ΡΠΈΠ½, ΠΆΠ΅Π½ΡΠΈΠ½ Ρ ΠΏΡΠΈΠ²ΡΡΠ½ΡΠΌ Π½Π΅Π²ΡΠ½Π°ΡΠΈΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΈ Π±Π΅ΡΠΏΠ»ΠΎΠ΄Π½ΡΡ
ΠΆΠ΅Π½ΡΠΈΠ½, ΠΏΠΎΠ΄Π²Π΅ΡΠ³Π°ΡΡΠΈΡ
ΡΡ Π²ΡΠΏΠΎΠΌΠΎΠ³Π°ΡΠ΅Π»ΡΠ½ΡΠΌ ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΡΠΌ ΡΠ΅Ρ
Π½ΠΎΠ»ΠΎΠ³ΠΈΡΠΌ. ΠΠΎΠ»ΡΡΠΈΠ½ΡΡΠ²ΠΎ Π·ΡΠΈΡ
ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΉ ΠΏΠΎΠΊΠ°Π·Π°Π»ΠΎ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΡΡ ΡΠ²ΡΠ·Ρ ΠΌΠ΅ΠΆΠ΄Ρ Π½Π°Π»ΠΈΡΠΈΠ΅ΠΌ ΡΠΈΡΠ΅ΠΈΠΎΠ΄Π½ΡΡ
Π°ΡΡΠΎΠ°Π½ΡΠΈΡΠ΅Π», Π±Π΅ΡΠΏΠ»ΠΎΠ΄ΠΈΠ΅ΠΌ ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΡΠΌ ΡΠΈΡΠΊΠΎΠΌ Π½Π΅Π²ΡΠ½Π°ΡΠΈΠ²Π°Π½ΠΈΡ. ΠΠ΄Π΅ΠΊΠ²Π°ΡΠ½ΡΠΉ ΡΡΠΎΠ²Π΅Π½Ρ ΡΠΈΡΠΊΡΠ»ΠΈΡΡΡΡΠΈΡ
Π² ΠΊΡΠΎΠ²ΠΈ Π³ΠΎΡΠΌΠΎΠ½ΠΎΠ² ΡΠΈΡΠΎΠ²ΠΈΠ΄Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΏΡΠ΅Π΄ΠΌΠ΅ΡΠΎΠΌ βΠΏΠ΅ΡΠ²ΠΎΠΉ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎΡΡΠΈ" Π΄Π»Ρ Π½ΠΎΡΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΡΠ½ΠΊΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΡΡΡ Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·Ρ Π½Π΅Π²ΡΠ½Π°ΡΠΈΠ²Π°Π½ΠΈΡ Ρ Π°ΡΡΠΎΠΈΠΌΠΌΡΠ½Π½ΡΠΌΠΈ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΠΌΠΈ ΡΠΈΡΠΎΠ²ΠΈΠ΄Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ ΠΈ ΡΠΈΡΠΊΡΠ»ΡΡΠΈΠ΅ΠΉ Π°Π½ΡΠΈΡΠΎΡΡΠΎΠ»ΠΈΠΏΠΈΠ΄Π½ΡΡ
Π°Π½ΡΠΈΡΠ΅Π». ΠΡΠ° Π°ΡΡΠΎΡΠΈΠ°ΡΠΈΡ Π²ΠΎΠ·Π½ΠΈΠΊΠ»Π° Π½Π΅ ΡΠ»ΡΡΠ°ΠΉΠ½ΠΎ. ΠΠΎΠ·ΠΌΠΎΠΆΠ½ΡΠΌ ΠΌΠ΅Ρ
Π°Π½ΠΈΠ·ΠΌΠΎΠΌ ΡΠ°ΠΊΠΎΠΉ Π²Π·Π°ΠΈΠΌΠΎΡΠ²ΡΠ·ΠΈ ΡΠ²Π»ΡΠ΅ΡΡΡ ΡΠΎΡ ΡΠ°ΠΊΡ, ΡΡΠΎ Π½Π°Π»ΠΈΡΠΈΠ΅ Π°Π½ΡΠΈΡΠΈΡΠ΅ΠΎΠΈΠ΄Π½ΡΡ
Π°Π½ΡΠΈΡΠ΅Π» ΠΎΡΡΠ°ΠΆΠ°Π΅Ρ Π³Π΅Π½Π΅ΡΠ°Π»ΠΈΠ·ΠΎΠ²Π°Π½Π½ΡΡ Π°ΠΊΡΠΈΠ²Π°ΡΠΈΡ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ ΠΈ ΡΡΠΈΠ»ΠΈΠ²Π°Π΅Ρ Π°ΡΡΠΎΠΈΠΌΠΌΡΠ½Π½ΡΠΉ ΠΏΡΠΎΡΠ΅ΡΡ, Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΡΠΉ ΠΏΡΠΎΡΠΈΠ² ΡΠ΅ΡΠΎΠΏΠ»Π°ΡΠ΅Π½ΡΠ°ΡΠ½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ
Features of lipid metabolism and bone metabolism in elderly women
We studied 65 elderly women bone turnover markers and investigated for osteoporosis and to assess lipid profile. In the study of the risk of osteoporosis is set significantly more rapid loss of BMD in women mnogorozhashih both trabecular and cortical bone in the structures. Infringing content lipoprotein spectrum of blood were found in all women surveyed, but the extent of these changes was also more pronounced in multiparous womenΠ£ 65 ΠΏΠΎΠΆΠΈΠ»ΡΡ
ΠΆΠ΅Π½ΡΠΈΠ½ ΠΈΠ·ΡΡΠ΅Π½ ΠΊΠΎΡΡΠ½ΡΠΉ ΠΎΠ±ΠΌΠ΅Π½ ΠΈ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Ρ ΠΌΠ°ΡΠΊΠ΅ΡΡ ΠΎΡΡΠ΅ΠΎΠΏΠΎΡΠΎΠ·Π°, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΎΡΠ΅Π½Π΅Π½ Π»ΠΈΠΏΠΈΠ΄Π½ΡΠΉ ΡΠΏΠ΅ΠΊΡΡ. ΠΡΠΈ ΠΈΠ·ΡΡΠ΅Π½ΠΈΠΈ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ ΡΠΈΡΠΊΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΎΡΡΠ΅ΠΎΠΏΠΎΡΠΎΠ·Π° ΡΡΡΠ°Π½ΠΎΠ²Π»Π΅Π½Π° Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½Π°Ρ Π±ΠΎΠ»Π΅Π΅ Π±ΡΡΡΡΠ°Ρ ΠΏΠΎΡΠ΅ΡΡ ΠΠΠΠ’ Ρ ΠΌΠ½ΠΎΠ³ΠΎΡΠΎΠΆΠ°ΡΠΈΡ
ΠΆΠ΅Π½ΡΠΈΠ½ ΠΊΠ°ΠΊ Π² ΡΡΠ°Π±Π΅ΠΊΡΠ»ΡΡΠ½ΡΡ
, ΡΠ°ΠΊ ΠΈ Π² ΠΊΠΎΡΡΠΈΠΊΠ°Π»ΡΠ½ΡΡ
ΠΊΠΎΡΡΠ½ΡΡ
ΡΡΡΡΠΊΡΡΡΠ°Ρ
. ΠΠ°ΡΡΡΠ΅Π½ΠΈΡ ΡΠΎΠ΄Π΅ΡΠΆΠ°Π½ΠΈΡ Π»ΠΈΠΏΠΎΠΏΡΠΎΡΠ΅ΠΈΠ½ΠΎΠ²ΠΎΠ³ΠΎ ΡΠΏΠ΅ΠΊΡΡΠ° ΠΊΡΠΎΠ²ΠΈ Π²ΡΡΠ²Π»Π΅Π½Ρ Ρ Π²ΡΠ΅Ρ
ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½Π½ΡΡ
ΠΆΠ΅Π½ΡΠΈΠ½, ΠΎΠ΄Π½Π°ΠΊΠΎ ΡΡΠ΅ΠΏΠ΅Π½Ρ ΡΡΠΈΡ
ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΠΉ Π±ΡΠ»Π° Π±ΠΎΠ»Π΅Π΅ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠΉ ΡΠ°ΠΊΠΆΠ΅ Ρ ΠΌΠ½ΠΎΠ³ΠΎΡΠΎΠΆΠ°Π²ΡΠΈΡ
ΠΆΠ΅Π½ΡΠΈ
To the question about the study of genetic factors of cardiovascular diseases in women of postmenopausal age
Cardiovascular disease is one of the most frequent reasons of death among the women of menopausal age. In addition to the hormonal disorders, which is accompanying this period of life, there is no doubt in presence of genetic predisposition to the development of cardiovascular diseases. The connection between the risk of the development of cardiovascular diseases and increased levels of PAI-1 in the blood, due to the presence of the 4G allele of PAI-1 and genetic polymorphism of MTHFR in genotype, was examined in this article. The study of genetic factors, which play a role in the development of cardiovascular diseases, indicates, that women of postmenopausal age are at the high risk of the listed diseases, and this should be considered during the selecting the optimal method of treatment of menopausal disorders.Π‘Π΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΠ°Ρ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠ΄Π½ΠΎΠΉ ΠΈΠ· ΡΠ°ΠΌΡΡ
ΡΠ°ΡΡΡΡ
ΠΏΡΠΈΡΠΈΠ½ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΠΈ ΠΆΠ΅Π½ΡΠΈΠ½ ΠΊΠ»ΠΈΠΌΠ°ΠΊΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°. ΠΠΎΠΌΠΈΠΌΠΎ Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΡΡ
Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ, ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠΈΡ
ΡΡΠΎΠΌΡ ΠΏΠ΅ΡΠΈΠΎΠ΄Ρ ΠΆΠΈΠ·Π½ΠΈ, Π² Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ Π½Π΅Ρ ΡΠΎΠΌΠ½Π΅Π½ΠΈΠΉ Π² Π½Π°Π»ΠΈΡΠΈΠΈ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΡΠ΅Π΄ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΠΊ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΡΡΡ ΡΠ²ΡΠ·Ρ ΠΌΠ΅ΠΆΠ΄Ρ ΡΠΈΡΠΊΠΎΠΌ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΡΡΠΎΠ²Π½Ρ Π ΠΠ Π² ΠΊΡΠΎΠ²ΠΈ, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠ΅ΠΌ Π² ΠΈΡ
Π³Π΅Π½ΠΎΡΠΈΠΏΠ΅ -4G Π°Π»Π»Π΅Π»Ρ Π³Π΅Π½Π° Π ΠΠ ΠΈ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌΠ° ΠΠ’ΠΠ€Π . ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ², ΠΈΠ³ΡΠ°ΡΡΠΈΡ
ΡΠΎΠ»Ρ Π² ΡΠ°Π·Π²ΠΈΡΠΈΠΈ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ, ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΡΡ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ ΠΆΠ΅Π½ΡΠΈΠ½Ρ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΡΠΎΡΡΠ°Π²Π»ΡΡΡ Π³ΡΡΠΏΠΏΡ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ° ΠΏΠΎ ΠΏΠ΅ΡΠ΅ΡΠΈΡΠ»Π΅Π½Π½ΡΠΌ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΠΌ ΠΈ ΡΡΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ ΡΡΠΈΡΡΠ²Π°ΡΡ ΠΏΡΠΈ Π²ΡΠ±ΠΎΡΠ΅ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π°Π»ΡΠ½ΡΡ
ΡΠ°ΡΡΡΡΠΎΠΉΡΡΠ²
About the study the clinical data in women in early natural and surgical postmenopausal women
Climacteric syndrome remains an urgent problem today. The climax is both the norm and disease: the norm because the menopause in the female body is a natural phenomenon, but a disease because it is a persistent violation of the regulation, leading eventually to decreased viability of the organism. We examined 207 women aged 40-55 years with climacteric syndrome in early natural (110 women) and surgical postmenopausal (97 women). The study of clinical data revealed some differences in the occurrence of menopausal women in early natural and surgical postmenopausal women.ΠΠ»ΠΈΠΌΠ°ΠΊΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠΈΠ½Π΄ΡΠΎΠΌ ΠΎΡΡΠ°Π΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΎΠΉ ΠΈ Π½Π° ΡΠ΅Π³ΠΎΠ΄Π½ΡΡΠ½ΠΈΠΉ Π΄Π΅Π½Ρ. ΠΊΠ»ΠΈΠΌΠ°ΠΊΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠ΄Π½ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎ ΠΈ Π½ΠΎΡΠΌΠΎΠΉ ΠΈ Π±ΠΎΠ»Π΅Π·Π½ΡΡ: Π½ΠΎΡΠΌΠΎΠΉ ΠΏΠΎΡΠΎΠΌΡ, ΡΡΠΎ ΠΊΠ»ΠΈΠΌΠ°ΠΊΡ Π² ΠΆΠ΅Π½ΡΠΊΠΎΠΌ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ΅ ΡΠ²Π»Π΅Π½ΠΈΠ΅ Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅ΡΠ½ΠΎΠ΅, Π° Π±ΠΎΠ»Π΅Π·Π½ΡΡ ΠΏΠΎΡΠΎΠΌΡ, ΡΡΠΎ ΡΡΠΎ ΡΡΠΎΠΉΠΊΠΎΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ ΡΠ΅Π³ΡΠ»ΡΡΠΈΠΈ, ΠΏΡΠΈΠ²ΠΎΠ΄ΡΡΠ΅Π΅ Π² ΠΊΠΎΠ½Π΅ΡΠ½ΠΎΠΌ ΠΈΡΠΎΠ³Π΅ ΠΊ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΠΆΠΈΠ·Π½Π΅ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ°. ΠΠ°ΠΌΠΈ Π±ΡΠ»ΠΎ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 207 ΠΆΠ΅Π½ΡΠΈΠ½ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 40-55 Π»Π΅Ρ Ρ ΠΊΠ»ΠΈΠΌΠ°ΠΊΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ Π² ΡΠ°Π½Π½Π΅ΠΉ Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ (110 ΠΆΠ΅Π½ΡΠΈΠ½) ΠΈ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π΅ (97 ΠΆΠ΅Π½ΡΠΈΠ½). ΠΠ·ΡΡΠ΅Π½ΠΈΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π΄Π°Π½Π½ΡΡ
Π²ΡΡΠ²ΠΈΠ»ΠΎ Π½Π΅ΠΊΠΎΡΠΎΡΡΠ΅ ΡΠ°Π·Π»ΠΈΡΠΈΡ Π² ΠΏΡΠΎΡΠ΅ΠΊΠ°Π½ΠΈΠΈ ΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Ρ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ Π² ΡΠ°Π½Π½Π΅ΠΉ Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΈ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π΅
Features of clinical data in women in early surgical postmenopausal women
Surgical deactivation of ovarian function in women of reproductive age remains one of the urgent problems of modern medicine. This analysis was performed in 60 women of the main group aged 40-55 years in early surgical postmenopausal women who underwent abdominal gynecological operations with ovarian excision. Indications for surgical interventions on the organs of the reproductive system in women are ovarian tumors, combined pathology of the reproductive system, severe purulent processes of the genitals and others, the volume of which includes removal of the ovaries.Π₯ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²ΡΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΠ½ΠΊΡΠΈΠΈ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ² Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΠΎΡΡΠ°Π΅ΡΡΡ ΠΎΠ΄Π½ΠΎΠΉ ΠΈΠ· Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΡ
ΠΏΡΠΎΠ±Π»Π΅ΠΌ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Ρ. ΠΠ°Π½Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· Π±ΡΠ» ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ Ρ 60 ΠΆΠ΅Π½ΡΠΈΠ½ ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡ 40 Π΄ΠΎ 55 Π»Π΅Ρ Π² ΡΠ°Π½Π½Π΅ΠΉ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π΅, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΏΠ΅ΡΠ΅Π½Π΅ΡΠ»ΠΈ Π°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΡΠ΅ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ Ρ ΡΠ΄Π°Π»Π΅Π½ΠΈΠ΅ΠΌ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ². ΠΠΎΠΊΠ°Π·Π°Π½ΠΈΡΠΌΠΈ Π΄Π»Ρ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΡΡ
Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ² Π½Π° ΠΎΡΠ³Π°Π½Π°Ρ
ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΡΠ²Π»ΡΡΡΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ², ΡΠΎΡΠ΅ΡΠ°Π½Π½Π°Ρ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ, ΡΡΠΆΠ΅Π»ΡΠ΅ Π³Π½ΠΎΠΉΠ½ΡΠ΅ ΠΏΡΠΎΡΠ΅ΡΡΡ Π³Π΅Π½ΠΈΡΠ°Π»ΠΈΠΉ ΠΈ Π΄ΡΡΠ³ΠΈΠ΅, ΠΎΠ±ΡΠ΅ΠΌ ΠΊΠΎΡΠΎΡΡΡ
Π²ΠΊΠ»ΡΡΠ°Π΅Ρ ΡΠ΄Π°Π»Π΅Π½ΠΈΠ΅ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ²
THE VALUE OF ANTIPHOSPHOLIPID ANTIBODIES CIRCULATION IN WOMEN WITH AUTOIMMUNE DISEASES OF THYROID GLAND AND MISCARRIAGE IN HISTORY
In the world literature many works which main object of studying are women with repeated miscarriage and infertile women after IVF are published. Majority of these researches demonstrated significant association between the circulation of thyroid autoantibodies, infertility and high risk of fetal loss. Adequate level of thyroid hormones is necessity for normal functioning of reproductive system. In this article the association of miscarriage and autoimmune diseases of thyroid gland is considered. This association arose not incidentally perhaps the mechanism of such interrelation is that fact that existence of antibodies reflects the general activation of immune system and increases autoimmune process against feto-placental system. Objective: to investigate spectrum of antiphospholipid antibodies in patients with various forms of autoimmune thyroid disease and a history of recurrent pregnancy loss. Materials and Methods: 154 women were involved including 112 women with autoimmune thyroid disease (Graves' disease, autoimmune thyroiditis, postpartum thyroiditis) and 42 with miscarriage history, but without thyroid disease. Results: there is no significant difference between the frequency of detection of antiphospholipid syndrome (APS) among women with ATD and without ATD and with anamnesis of miscarriage. However, APS most often detected in patients with thyrotoxicosis (45%; p <0.005). High incidence of APS among women with autoimmune thyroiditis (33.33%) also identified. Conclusion: check up of thyroid status for all pregnant women with increased thyroid function could be recommended. Early detection and correction of the hemostatic system and thyroid dysfunction during pregnancy will help to prevent complications