Implementation of fuzzy analytical hierarchy process on notebook selection

Notebooks are technological devices widely adopted to assist in human daily life including learning, business, communication and other tasks. Equipped with the distinctive features, notebook was facilitated more simply for one touch screen basis to enable freely in exploring the users’ creativity. This study attempts to examine the process of selecting notebook brand among the consumers. Using AHP (Analytical Hierarchy Process) to help decision support system in the selection of Notebook from decision support systems designed to enhance all decision-process through identifying problems, selecting relevant data and defining the approaches was used to evaluate the selection of alternatives in the decision-making process. The finding reveals that the visibility of decision making into the ranking of priority with alternative choice of notebook can be viewed as follows Zyrex 16%, HP 15%, Asus 14%, Apple 13%, Samsung and Axioo 11%, Acer and Toshiba with priority 10%

Nanoparticle of Telmisartan and Polyvinylpyrrolidone K-30: Characterization and Dissolution Study

Background: Telmisartan (TEL) is an orally active nonpeptide angiotensin II antagonist drug. The drug acts on a subtype of AT1 receptors, which serves to cope with high blood pressure (hypertension). TEL is a class II Biopharmaceutical Classification System (BCS), which is a drug that has low solubility in water and high permeability. Objectives: This study aims to determine the effect of the formation of TEL-PVP K-30 nanoparticles through the solvent drop grinding method on the characteristics of physicochemical properties and the rate of dissolution of TEL. Methods: Nanoparticles are made in 2 formulas, namely formula 1: 1 and formula 1: 2. Results: Characterization of the Particle Size Analyzer (PSA) was performed with the results of the formula 1:1 24nm, and the formula 1:2 35nm. X-ray Diffraction (XRD) analysis resulted from a decrease in the intensity of crystallinity degrees. Fourier Transform Infrared (FT-IR) Spectroscopy occurs wave number shift. Differential Scanning Calorimetry (DSC) decreases in melting point. The dissolution rate was carried out using a pH 7.5 phosphate tart medium. Conclusion: The result of the dissolution rate has increased by 3.3 times for formula 1:1 and 2.9 times for formula 1:2. Keywords: Telmisartan; polyvinylpyrrolidone K-30; nanoparticles; and solvent drop grinding