626 research outputs found

    The live sheep export industry

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    Australia\u27s live sheep trade to Middle Eastern countries is an important export industry. However, about 2 per cent of the sheep die, mainly during the sea voyage. The Western Australian Department of Agriculture has conducted a major research programme to improve the health and welfare of sheep during live export. The programme has\u27examined many aspects of the export sheep industry, and a substantial part of it has focused on why sheep die during sea transport

    Landscape of overlapping gene expression in the equine placenta

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    Increasing evidence suggests that overlapping genes are much more common in eukaryotic genomes than previously thought. These different-strand overlapping genes are potential sense-antisense (SAS) pairs, which might have regulatory effects on each other. In the present study, we identified the SAS loci in the equine genome using previously generated stranded, paired-end RNA sequencing data from the equine chorioallantois. We identified a total of 1261 overlapping loci. The ratio of the number of overlapping regions to chromosomal length was numerically higher on chromosome 11 followed by chromosomes 13 and 12. These results show that overlapping transcription is distributed throughout the equine genome, but that distributions differ for each chromosome. Next, we evaluated the expression patterns of SAS pairs during the course of gestation. The sense and antisense genes showed an overall positive correlation between the sense and antisense pairs. We further provide a list of SAS pairs with both positive and negative correlation in their expression patterns throughout gestation. This study characterizes the landscape of sense and antisense gene expression in the placenta for the first time and provides a resource that will enable researchers to elucidate the mechanisms of sense/antisense regulation during pregnancy

    A spectral atlas of post-main-sequence stars in omega Centauri: kinematics, evolution, enrichment and interstellar medium

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    We present a spectral atlas of the post-main-sequence population of the most massive Galactic globular cluster, omega Centauri. Spectra were obtained of more than 1500 stars selected as uniformly as possible from across the (B, B-V) colour-magnitude diagram of the proper motion cluster member candidates of van Leeuwen et al. (2000). The spectra were obtained with the 2dF multi-fibre spectrograph at the Anglo Australian Telescope, and cover the approximate range lambda~3840-4940 Angstroem. We measure the radial velocities, effective temperatures, metallicities and surface gravities by fitting ATLAS9 stellar atmosphere models. We analyse the cluster membership and stellar kinematics, interstellar absorption in the Ca II K line at 3933 Angstroem, the RR Lyrae instability strip and the extreme horizontal branch, the metallicity spread and bimodal CN abundance distribution of red giants, nitrogen and s-process enrichment, carbon stars, pulsation-induced Balmer line emission on the asymptotic giant branch (AGB), and the nature of the post-AGB and UV-bright stars. Membership is confirmed for the vast majority of stars, and the radial velocities clearly show the rotation of the cluster core. We identify long-period RR Lyrae-type variables with low gravity, and low-amplitude variables coinciding with warm RR Lyrae stars. A barium enhancement in the coolest red giants indicates that 3rd dredge-up operates in AGB stars in omega Cen. This is distinguished from the pre-enrichment by more massive AGB stars, which is also seen in our data. The properties of the AGB, post-AGB and UV-bright stars suggest that RGB mass loss may be less efficient at very low metallicity, [Fe/H]<<-1, increasing the importance of mass loss on the AGB. The catalogue and spectra are made available via CDS.Comment: accepted for publication in MNRA

    Predicting Online and Offline Civic Participation among Young Czech Roma: The Roles of Resources, Community Perceptions and Social Norms

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    Roma in the Czech Republic represent a large ethnic minority that faces intolerance and social exclusion. This study aims to describe factors that boost civic participation among Roma adolescents and emerging adults. Specifically, it asks whether different factors apply to Roma and members of the majority, and whether different factors boost offline and online participation. Survey data were analysed from Roma (n = 157) and majority (n = 573) participants between the ages of 15 and 28. Hierarchical regression models suggested that certain factors (a sense of collective influence and peer participatory norm) predict all forms of civic participation, regardless of ethnicity. For Roma youth, in contrast with the majority, offline participation was associated with a perceived lack of opportunities and unmet needs in their communities, which suggests that their offline civic participation might be a reaction to perceived communal problems. Finally, a lack of education was identified as a major explanation for lower rates of online participation among Roma

    A randomised, feasibility trial of an Exercise and Nutrition-based Rehabilitation programme (ENeRgy) in people with cancer

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    From Wiley via Jisc Publications RouterErna Haraldsdottir - ORCID: 0000-0003-4891-0743 https://orcid.org/0000-0003-4891-0743Background: Despite rehabilitation being increasingly advocated for people living with incurable cancer, there is limited evidence supporting efficacy or component parts. The progressive decline in function and nutritional in this population would support an approach that targets these factors. This trial aimed to assess the feasibility of an exercise and nutrition based rehabilitation programme in people with incurable cancer. Methods: We randomized community dwelling adults with incurable cancer to either a personalized exercise and nutrition based programme (experimental arm) or standard care (control arm) for 8 weeks. Endpoints included feasibility, quality of life, physical activity (step count), and body weight. Qualitative and health economic analyses were also included. Results: Forty‐five patients were recruited (23 experimental arm, 22 control arm). There were 26 men (58%), and the median age was 78 years (IQR 69–84). At baseline, the median BMI was 26 kg/m2 (IQR: 22–29), and median weight loss in the previous 6 months was 5% (IQR: −12% to 0%). Adherence to the experimental arm was >80% in 16/21 (76%) patients. There was no statistically significant difference in the following between trial arms: step count − median % change from baseline to endpoint, per trial arm (experimental −18.5% [IQR: −61 to 65], control 5% [IQR: −32 to 50], P = 0.548); weight − median % change from baseline to endpoint, per trial arm (experimental 1%[IQR: −3 to 3], control −0.5% [IQR: −3 to 1], P = 0.184); overall quality of life − median % change from baseline to endpoint, per trial arm (experimental 0% [IQR: −20 to 19], control 0% [IQR: −23 to 33], P = 0.846). Qualitative findings observed themes of capability, opportunity, and motivation amongst patients in the experimental arm. The mean incremental cost of the experimental arm versus control was £‐319.51 [CI −7593.53 to 6581.91], suggesting the experimental arm was less costly. Conclusions: An exercise and nutritional rehabilitation intervention is feasible and has potential benefits for people with incurable cancer. A larger trial is now warranted to test the efficacy of this approach.12pubpub
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