Achalasia and associated esophageal cancer risk: What lessons can we learn from the molecular analysis of Barrett's–associated adenocarcinoma?

Idiopathic achalasia and Barrett's esophagus (BE) are preneoplastic conditions of the esophagus. BE increases the risk of esophageal adenocarcinoma (

Detection and molecular characterization of gastrointestinal cancers and premalignant lesions

The current thesis combines basic and translational studies on gastrointestinal carcinogenesis. The first part (Chapters 2-5) focused on the detection and treatment of pancreatic cancer. The second part (Chapters 6-8) investigated gene-regulators of gastrointestinal embryogenesis in esophageal cancer pathogenesis