10 research outputs found
Immunogenicity and efficacy of oral vaccines in developing countries: lessons from a live cholera vaccine
Oral vaccines, whether living or non-living, viral or bacterial, elicit diminished immune responses or have lower efficacy in developing countries than in developed countries. Here I describe studies with a live oral cholera vaccine that include older children no longer deriving immune support from breast milk or maternal antibodies and that identify some of the factors accounting for the lower immunogenicity, as well as suggesting counter-measures that may enhance the effectiveness of oral immunization in developing countries. The fundamental breakthrough is likely to require reversing effects of the 'environmental enteropathy' that is often present in children living in fecally contaminated, impoverished environments
Intensifying responsiveness towards neglected intestinal helminth infections in a resource-constrained setting
Development and characterization of 15 polymorphic microsatellite loci in Sonneratia alba (Lythraceae) using next-generation sequencing
10.1007/s12686-012-9650-5Conservation Genetics Resources43811-81
Isolation and characterization of 14 microsatellite markers for Rhizophora mucronata (Rhizophoraceae) and their potential use in range-wide population studies
10.1007/s12686-012-9681-yConservation Genetics Resources44951-95