The Limit Behavior Of The Trajectories of Dissipative Quadratic Stochastic Operators on Finite Dimensional Simplex

The limit behavior of trajectories of dissipative quadratic stochastic operators on a finite-dimensional simplex is fully studied. It is shown that any dissipative quadratic stochastic operator has either unique or infinitely many fixed points. If dissipative quadratic stochastic operator has a unique point, it is proven that the operator is regular at this fixed point. If it has infinitely many fixed points, then it is shown that $\omega-$ limit set of the trajectory is contained in the set of fixed points.Comment: 14 pages, accepted in Difference Eq. App

Creativity, thinking style and mental disorders

Creativity is considered as a soundand desirable feature. In cognitive approach, it is assumed that human though effects on his behavior. All human's success and progress depends on dynamic, fruitful and effective thinking. As we know, thinking style of people with his attitude and lifestyle. People with pragmatismthinking style are more flexible and show more creativity and innovation than the others and also they have enough skill to plan for unexpected days. Creativity has a significant effect on reduction of anxiety and depression, enhancing of better adaptability, self-efficiency and personal development. Creating and enhancing of creativity in the form of meta-cognitive,  character and motivation components can have a high effect on improving mental health, self-efficiency and dealing with mental stress. Creativity can also treat the mental disorders. Today, methods to improvecreativity are a technique to enhance the mental health in the society. In this article, we study the relationship among the creativity, thinking styles and a number of mental disorders.Keywords: Creativity, Thinking Style, Mental Disorde

Entrepreneurship Education and Experiential Learning in Higher Education

Entrepreneurship education (EE) and experiential learning can be delivered in several ways depending on the program design, the course\u27s purpose, and the learning outcomes. With the distinct stages of doing, observing, thinking, and planning, Kolb\u27s experiential learning theory is favored in EE. Additionally, EE programs and courses can be categorized in the three instructional themes of teaching about, for, or through entrepreneurship. Each theme offers a particular purpose, unique learning objectives, specific teaching methodology, and different student engagement levels. Due to the various references to EE, this exploratory qualitative study presents five selected entrepreneurship project course examples at Southern New Hampshire University (SNHU) using semi-structured interviews. The research objectives aim to (1) share entrepreneurial education teaching practices at SNHU, and (2) collect information on how instructors measure student engagement, course/project impact, reflection, and assessment practices. Common elements and approaches in the for entrepreneurship instructional theme -also known as learning by doing include (a) the learning environment, (b) real-life projects and clients, (c) reflection practices, (d) active student engagement, and (e) subject matter expertise by the instructor

Stemming text-based web page classification using machine learning algorithms: a comparison

The research aim is to determine the effect of word-stemming in web pages classification using different machine learning classifiers, namely Naive Bayes (NB), k-Nearest Neighbour (k-NN), Support Vector Machine (SVM) and Multilayer Perceptron (MP). Each classifiers' performance is evaluated in term of accuracy and processing time. This research uses BBC dataset that has five predefined categories. The result demonstrates that classifiers' performance is better without word stemming, whereby all classifiers show higher classification accuracy, with the highest accuracy produced by NB and SVM at 97% for F1 score, while NB takes shorter training time than SVM. With word stemming, the effect on training and classification time is negligible, except on Multilayer Perceptron in which word stemming has effectively reduced the training time

Virial mass in DGP brane cosmology

We study the virial mass discrepancy in the context of a DPG brane-world scenario and show that such a framework can offer viable explanations to account for the mass discrepancy problem. This is done by defining a geometrical mass $\mathcal{N}$ that we prove to be proportional to the virial mass. Estimating $\mathcal{N}$ using observational data, we show that it behaves linearly with $r$ and has a value of the order of $M_{200}$, pointing to a possible resolution of the virial mass discrepancy. We also obtain the radial velocity dispersion of galaxy clusters and show that it is compatible with the radial velocity dispersion profile of such clusters. This velocity dispersion profile can be used to differentiate various models predicting the virial mass.Comment: 12 pages, 1 figure, to appear in CQ

Inter-individual stereotypy of the Platynereis larval visual connectome

This is the final version of the article. Available from the publisher via the DOI in this record.Developmental programs have the fidelity to form neural circuits with the same structure and function among individuals of the same species. It is less well understood, however, to what extent entire neural circuits of different individuals are similar. Previously, we reported the neuronal connectome of the visual eye circuit from the head of a Platynereis dumerilii larva (Randel et al., 2014). We now report a full-body serial section transmission electron microscopy (ssTEM) dataset of another larva of the same age, for which we describe the connectome of the visual eyes and the larval eyespots. Anatomical comparisons and quantitative analyses of the two circuits reveal a high inter-individual stereotypy of the cell complement, neuronal projections, and synaptic connectivity, including the left-right asymmetry in the connectivity of some neurons. Our work shows the extent to which the eye circuitry in Platynereis larvae is hard-wired.The research leading to these results received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007–2013)/European Research Council Grant Agreement 260821.European Research Council (ERC): Grant Agreement 260821, Gaspar Jekel

Effects of the Agents Influencing the Serotonergic and Cannabinoid Systems on Memory in the Avoidance Test in Mice

Adult male albino mice in a shuttle box system were used for examination of learning for avoidance behavior and its deactivation. We measured the step-through latency in the acquisition of the task (STLa) before injections of the drugs tested (fluoxetine and URB597 (a serotonin reuptake inhibitor, SSRI, and an agent preventing decomposition of endocannabinoids, respectively) and the respective latency 24 h later after injections of these agents (STLr); total time spent in the dark compartment (TDC) was also measured in these situations. In mice that received fluoxetine (5, 10, and 20 mg/kg), the STLr were longer than those in the control, and the difference was significant at 10 mg/kg. Injections of URB597 decreased the STLr and, at medium and high doses (0.3 and 1.0 mg/kg), provided significant differences. All doses of fluoxetine led to significant decreases in the TDC values, while injections of URB597 increased this index (at 0.3 and 1.0 mg/kg, the shifts were significant). Combined injections of fluoxetine and URB597 (5 + 0.1, 10 + 0.3, and 20 + 1.0 mg/kg) increased the STLr values and decreased TDC values to the levels comparable with those at isolated injections of fluoxetine in the respective doses. Thus, fluoxetine improved memory, while URB597 impaired it; fluoxetine is capable of nullifying negative effects of URB597.У дорослих білих мишей-самців досліджували навчання поведінці уникання та деактивацію цього процесу в системі із човниковою камерою. Виміряли латентні періоди перетину межі при навчанні дó ін’єкції тестованих агентів – флуоксетину (інгібітора зворотного захоплення серотоніну, SSRS) та URB597 (речовини, що перешкоджає декомпозиції ендоканабіноїдів) і після таких ін’єкцій (STLa і STLr) відповідно; визначали також загальний час, проведений у темному компартменті в даних ситуаціях (TDC). У мишей, які отримували флуоксетин (5, 10 або 20 мг/кг), STLr ставали більшими, ніж у контролі, причому в разі використання 10 мг/кг різниця середніх була вірогідною. Ін’єкції URB597 зменшували значення TDC, і при середніх і високих дозах (0.3 і 1.0 мг/кг) відмінності перевищували рівень вірогідності. Флуоксетин у всіх дозах зумовлював істотне зменшення значень TDC, а ін’єкції URB597 збільшували цей показник (при 0.3 та 1.0 мг/кг зрушення були вірогідними). Комбіновані ін’єкції флуоксетину та URB597 (5 + 0.1, 10 + 0.3 і 20 + + 1.0 мг/кг) призводили до збільшення значень STLr і зменшення TDC до рівнів, порівнянних із тими, які спостерігалися в умовах ізольованих уведень флуоксетину у відповідних дозах. Таким чином, флуоксетин покращував пам’ять, тоді як URB597 порушував її; флуоксетин має здатність нейтралізувати негативні ефекти URB597

Serum level of interleukin-6 in patients with oral tongue squamous cell carcinoma

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum levels of interleukin-6 in patients with oral tongue SCC. Materials and Methods: In a cross-sectional study, 17 patients with oral tongue SCC were compared with the same number of age- and gender-matched healthy subjects. Serum IL-6 level fluctuation was determined using an immunological technique, before detecting its possible association with the subjects' age, gender, drinking and smoking history, cancer site, and disease severity. Results: The intensity of serum IL-6 in patients with oral tongue SCC was statistically significantly higher than that in healthy subjects (P<0.001). Serum IL-6 level was independent of the patients' age, gender, smoking and drinking history as well as cancer stage. Conclusion: IL-6 is a valuable biomarker in the diagnosis of oral tongue SCC. Its high sensitivity makes prediction of this condition possible, while this biomarker can also be used to screen high-risk patients

Serum level of interleukin-6 in patients with oral tongue squamous cell carcinoma

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum levels of interleukin-6 in patients with oral tongue SCC. Materials and Methods: In a cross-sectional study, 17 patients with oral tongue SCC were compared with the same number of age- and gender-matched healthy subjects. Serum IL-6 level fluctuation was determined using an immunological technique, before detecting its possible association with the subjects' age, gender, drinking and smoking history, cancer site, and disease severity. Results: The intensity of serum IL-6 in patients with oral tongue SCC was statistically significantly higher than that in healthy subjects (P<0.001). Serum IL-6 level was independent of the patients' age, gender, smoking and drinking history as well as cancer stage. Conclusion: IL-6 is a valuable biomarker in the diagnosis of oral tongue SCC. Its high sensitivity makes prediction of this condition possible, while this biomarker can also be used to screen high-risk patients