Corneal thickness in children with growth hormone deficiency: The effect of GH treatment.

Abstract OBJECTIVE: The eye represents a target site for GH action, although few data are available in patients with GH deficiency (GHD). Our aim was to evaluate central corneal thickness (CCT) and intraocular pressure (IOP) values in GHD children to assess the role played by GHD or GH treatment on these parameters. DESIGN: In 74 prepubertal GHD children (51M, 23F, aged 10.4\ub12.4years) we measured CCT and IOP before and after 12months of treatment. A baseline evaluation was also made in 50 healthy children matched for age, gender and body mass index. The study outcome considered CCT and IOP during treatment and their correlations with biochemical and auxological data. RESULTS: No difference in CCT and IOP between GHD children at baseline and controls was found (all p>0.005). GHD children after 12months of therapy showed greater CCT (564.7\ub113.1\u3bcm) than both baseline values (535.7\ub117\u3bcm; p<0.001) and control subjects (536.2\ub112.5\u3bcm; p<0.001), with a concomitantly higher corrected mean IOP (15.6\ub10.7mmHg; p<0.001) than both baseline (12.5\ub10.8mmHg; p<0.001) and controls (12.3\ub10.5mmHg; p<0.001), without correlation with auxological and biochemical parameters. CONCLUSIONS: 12months of GH treatment in children with GHD, regardless of auxological and biochemical data, affect CCT and IOP. Our findings suggest careful ocular evaluation in these patients to prevent undesirable side effects during the follow-up

Rethinking energy security and services in practice: national vulnerability and three energy pathways in Tajikistan

To help answer questions about availability, accessibility, sustainability and other dimensions of energy security, the vulnerability approach concentrates the attention of policymakers on the assessment of risks associated with natural, technical, political and economic factors. This understanding, combined with a focus on energy services (e.g. lighting, heating, telecommunications, mobility, etc.) helps to prioritize actions to achieve the goal of energy security. This paper conceptualizes energy security as low vulnerability of vital energy systems and sustained provision of modern energy services. Taking Tajikistan as a case, this paper highlights key vulnerabilities including neglect of environmental conditions, insufficient energy production capacity, unreliable and expensive energy imports, dwindling power infrastructure causing technical and economic losses, inadequate transparency in the power sector, lack of regional cooperation in energy and water resources sharing, and inadequate financial resources to address these challenges. Three major proposals presented by the World Bank, the United Nations Development Program, and the Government of Tajikistan to achieve energy security in Tajikistan are evaluated. Specifically, they lack a focus on energy services and therefore overlook people's socio-cultural context and appropriate energy needs. This paper highlights energy services as critical to people’s wellbeing and socio-economic development

Aerial LiDAR Technology in Support to Avalanches Prevention and Risk Mitigation: AN Operative Application at "colle della Maddalena" (italy)

Abstract. Snow avalanches are the result of unstable snow masses that detach from steep slopes as consequence of changes in snowpack structure. Nowadays, remote sensing technologies can improve the knowledge of avalanches phenomenon. This work focuses on the use of high point density aerial LiDAR (Light Detection And Ranging) technology as support to avalanche events prevention and risk mitigation, by presenting an operative application at Colle della Maddalena (Italy), along the road SS n. 21, nearby the French state border. The area is often involved in intense avalanche events that adversely impact on traffic and freight transport. For this reason, regional administrations will activate the Avalanche Artificial Detachment Intervention Plan (PIDAV, 2012) in order to prevent and manage the avalanche risk in the study area, also adopting artificial detachment systems. Main aim of the present work was to generate high resolution information related to geomorphological characterization (i.e. digital elevation models, slope and aspect) of avalanche sites derived from LiDAR data processing, that will help involved authorities in the management of the avalanche control plan. Digital elevation models at 0.5 m of spatial resolution were generated together with relative tridimensional models. Secondly, a preliminary investigation about capabilities and limits of LiDAR technology was done in the identification of avalanche sites only relying on geomorphological information directly derived by LiDAR data processing. Results showed that position of avalanche sites were correctly identified while no information could be obtained about the extension of the sliding area and identification of detachment areas

Fattori di emissione dalla combustione di legna e pellet in piccoli apparecchi domestici

The aim of this study was to report emission factors of pollutants (i.e., carbon monoxide, nitrogen oxides, non-methane hydrocarbons, particulate matter, polycyclic aromatic hydrocarbons, dioxins) from biomass burning residential heating appliances. The influence of several factors such as biomass type, appliance and combustion cycle was investigated. Four manually fed (6-11 kW) firewood burning and two automatic wood pellets (8.8-25 kW) appliances were tested under real-world operating conditions in order to determine the actual environmental performance of the appliance. The experimental EFs were also compared with the values proposed by the European emission inventory guidebook used in the local inventory in order to evaluate their representativeness of real world emissions. The composite macropollutant EFs for manually fed appliances are: for CO 5858 g GJ-1, for NOx 122 g GJ-1, NMHC 542 g GJ-1, PM 254 g GJ-1, whereas emissions are much lower for automatic pellets appliances: CO 219 g GJ-1, for NOx 66 g GJ-1, NMHC 5 g GJ-1, PM 85 g GJ-1. The open fireplace appears to have very high emission factors, however traditional and advanced stoves show the highest overall CO EFs. Especially for the advanced stove real-world emissions are far worse than those measured under cycles used for type testing of residential solid fuel appliances. No great difference is observed for different firewood types in batch working appliances, diversely the quality of the pellets is observed to influence directly the emission performance of the automatic appliances. Benzo(b)fluoranthene is the PAH with the highest contribution (110 mg GJ-1 for manual appliances and 2 mg GJ-1 for automatic devices) followed by benzo(a)pyrene (77 mg GJ-1 for manual appliances and 0,8 mg GJ-1 for automatic devices)

Geophysical surveys integrated with rainfall data analysis for the study of soil piping phenomena occurred in a densely urbanized area in eastern Sicily

AbstractThe occurrence of strong and abrupt rainfall, together with a wrong land use planning and an uncontrolled urban development, can constitute a risk for infrastructure and population. The water flow in the subsoil, under certain conditions, may cause underground cavities formation. This phenomena known as soil piping can evolve and generate the surface collapse. It is clear that such phenomena in densely urbanized areas represent an unpredictable and consistent risk factor, which can interfere with social activities. In this study a multidisciplinary approach aimed to obtain useful information for the mitigation of the risks associated with the occurrence of soil piping phenomena in urban areas has been developed. This approach is aimed at defining the causes of sudden soil subsidence events, as well as the definition of the extension and possible evolution of these instability areas. The information obtained from rainfall data analysis, together with a study of the morphological, geological and hydrogeological characteristics, have allowed us to evaluate the causes that have led to the formation of soil pipes. Furthermore, performance of 3D electrical resistivity surveys in the area affected by the instability have allowed us to estimate their extension in the subsoil and identifying the presence of further areas susceptible to instability

Recent Developments and Formulations for Hydrophobic Modification of Carrageenan Bionanocomposites

Versatility of the anionic algal polysaccharide carrageenan has long been discussed and explored, especially for their affinity towards water molecules. While this feature is advantageous in certain applications such as water remediation, wound healing, etc., the usefulness of this biopolymer is extremely limited when it comes to applications such as food packaging. Scientists around the globe are carrying out research works on venturing diverse methods to integrate hydrophobic nature into these polysaccharides without compromising their other functionalities. Considering these foregoing studies, this review is designed to have an in-depth understanding of diverse methods and techniques adopted for tuning the hydrophobic nature of carrageenan-based bionanocomposites, both via surface alterations or by changes made to their chemical structure and attached functional groups. This review article mainly focuses on how the hydrophobicity of carrageenan bionanocomposites varies as a function of the type and refinement of carrageenan, and with the incorporation of additives including plasticisers, nanofillers, bioactive agents, etc. Incorporation of nanofillers such as polysaccharide-based nanoparticles, nanoclays, bioceramic and mineral based nanoparticles, carbon dots and nanotubes, metal oxide nanoparticles, etc., along with their synergistic effects in hybrid bionanocomposites are also dealt with in this comprehensive review article