1,113 research outputs found

    Multiscaling and Structure Functions in Turbulence: An Alternative Approach

    Full text link
    We propose an alternative formulation of structure functions for the velocity field in fully developed turbulence. Instead of averaging moments of the velocity differences as a function of the distance, we suggest to average moments of the distances as a function of the velocity difference. This is like an ``inverted'' structure function, with a different statistics. On the basis of shell model calculations we obtain a new multiscaling spectrum.Comment: 4 pages, REVTex, 4 figure

    Inducing phase-locking and chaos in cellular oscillators by modulating the driving stimuli

    Full text link
    Inflammatory responses in eucaryotic cells are often associated with oscillations in the nuclear-cytoplasmic translocation of the transcription factor NF-kB. In most laboratory realizations, the oscillations are triggered by a cytokine stimulus, like the tumor necrosis factor alpha, applied as a step change to a steady level. Here we use a mathematical model to show that an oscillatory external stimulus can synchronize the NF-kB oscillations into states where the ratios of the internal to external frequency are close to rational numbers. We predict a specific response diagram of the TNF-driven NF-kB system which exhibits bands of synchronization known as "Arnold tongues". Our model also suggests that when the amplitude of the external stimulus exceeds a certain threshold there is the possibility of coexistence of multiple different synchronized states and eventually chaotic dynamics of the nuclear NF-kB concentration. This could be used as a way of externally controlling immune response, DNA repair and apoptotic pathways.Comment: 12 pages, 3 figure

    Internal Waves in Nonhomogeneus Media

    Get PDF

    Entrainment of noise-induced and limit cycle oscillators under weak noise

    Full text link
    Theoretical models that describe oscillations in biological systems are often either a limit cycle oscillator, where the deterministic nonlinear dynamics gives sustained periodic oscillations, or a noise-induced oscillator, where a fixed point is linearly stable with complex eigenvalues and addition of noise gives oscillations around the fixed point with fluctuating amplitude. We investigate how each class of model behaves under the external periodic forcing, taking the well-studied van der Pol equation as an example. We find that, when the forcing is additive, the noise-induced oscillator can show only one-to-one entrainment to the external frequency, in contrast to the limit cycle oscillator which is known to entrain to any ratio. When the external forcing is multiplicative, on the other hand, the noise-induced oscillator can show entrainment to a few ratios other than one-to-one, while the limit cycle oscillator shows entrain to any ratio. The noise blurs the entrainment in general, but clear entrainment regions for limit cycles can be identified as long as the noise is not too strong.Comment: 27 pages in preprint style, 12 figues, 2 tabl

    Inverse Statistics in Economics : The gain-loss asymmetry

    Full text link
    Inverse statistics in economics is considered. We argue that the natural candidate for such statistics is the investment horizons distribution. This distribution of waiting times needed to achieve a predefined level of return is obtained from (often detrended) historic asset prices. Such a distribution typically goes through a maximum at a time called the {\em optimal investment horizon}, τρ\tau^*_\rho, since this defines the most likely waiting time for obtaining a given return ρ\rho. By considering equal positive and negative levels of return, we report on a quantitative gain-loss asymmetry most pronounced for short horizons. It is argued that this asymmetry reflects the market dynamics and we speculate over the origin of this asymmetry.Comment: Latex, 6 pages, 3 figure
    corecore