Hjerneskade og kørekort: Centrale problemstillinger og forslag til forbedring af praksis.

Hjerneskade kan påvirke en persons bilkørsel således, at pågældende ikke længere er en sikker bilist. Det kan være svært at observere de kognitive følgevirkninger, der påvirker bilkørsel. Derfor er det nødvendigt med grundig og systematisk køreevaluering efter en hjerneskade. Denne spørgeskemaundersøgelse af procedure og praksis mht. køreevaluering efter hjerneskade, foretaget på relevante afdelinger og institutioner i Danmark har vist, at køreevaluering efter hjerneskade ikke foretages systematisk i dagens Danmark. Konsekvensen er, at personer med hjerneskade, som er potentielt farlige i trafikken, kører bil alligevel. En lige så uhensigtsmæssig følge er, at personer med hjerneskade, som egner sig til at køre bil, afholder sig fra at gøre det, da de ikke længere føler sig sikre på, at de er i stand til det

Perceived Collective Use of Selection, Optimisation, and Compensation: Associations with Work Ability

Background: Individual use of selection, optimisation, and compensation (SOC) is positively associated with work ability; however, this association has never been explored at the group or leadership levels.Aim: The aim of this study is to explore the strength of associations between employee-rated use of SOC at the individual, group, and leadership levels and self-rated work ability among nurses. Method: A random sample of 2000 nurses were invited to participate in a questionnaire survey, among whom 785 responded.Results: Employee-rated use of SOC at the individual and group levels was positively associated with self-rated work ability when controlling for psychosocial working environment factors and health. The association was strongest at the group level.Conclusion: Efforts to enhance the collective use of SOC may prove beneficial to maintain the work ability of nurses and retain them in the profession

The Psychosocial Work Environment and Perceived Stress among Seniors with Physically Demanding Jobs:The SeniorWorkingLife Study

Background: Poor psychosocial work conditions are known to foster negative health consequences. While the existing literature on this topic focus mainly on white-collar workers, the influence of different aspects of the psychosocial work environment in physically demanding jobs remain understudied. Likewise, senior workers represent a population of the workforce at increased risk of adverse health outcomes and premature exit from the labour market. This study investigates the association between psychosocial work factors and perceived stress among the senior work force. Methods: Utilizing cross-sectional findings, this study reports associations between psychosocial factors (organizational justice, cooperation and collegial support, decision latitude, clarity of tasks, and quality of leadership) and the outcome of perceived stress quantified by Cohen’s Perceived Stress Scale (CPSS). Currently employed senior workers with physically demanding jobs were included in the analyses (n = 3386). Associations were modeled using general linear models with weights to make the estimates representative. Results: For all individually adjusted psychosocial variables, the category of “good” was consistently associated with lower stress scores compared to the categories of both “moderate” and “poor” (all p < 0.0001). Likewise, in the mutually adjusted analysis, the category of “good” was statistically different from “poor” for all included variables, while the category of “moderate” remained different from “poor” for “clarity of tasks”, “cooperation and collegial support”, and “decision latitude”. Conclusions: Among senior workers with physically demanding jobs, poor ratings of organizational factors related to the psychosocial work environment are consistently associated with high stress scores. Blue-collar occupations focusing primarily on physical risk factors are recommended to increase awareness on psychosocial aspects that may be relevant to the local work environment

Strong labour market inequality of opportunities at the workplace for supporting a long and healthy work-life:The SeniorWorkingLife study

Most European countries are gradually increasing the state pension age, but this may run counter to the capabilities and wishes of older workers. The objective of this study is to identify opportunities in the workplace for supporting a prolonged working life in different groups in the labour market. A representative sample of 11,200 employed workers &ge; 50 years responded to 15 questions in random order about opportunities at their workplace for supporting a prolonged working life. Respondents were stratified based on the Danish version of the International Standard Classification of Occupations (ISCO). Using frequency and logistic regression procedures combined with model-assisted weights based on national registers, results showed that the most common opportunities at the workplace were possibilities for more vacation, reduction of working hours, flexible working hours, access to treatment, further education and physical exercise. However, ISCO groups 5&ndash;9 (mainly physical work and shorter education) had in general poorer access to these opportunities than ISCO groups 1&ndash;4 (mainly seated work and longer education). Women had poorer access than men, and workers with reduced work ability had poorer access than those with full work ability. Thus, in contrast with actual needs, opportunities at the workplace were lower in occupations characterized by physical work and shorter education, among women and among workers with reduced work ability. This inequality poses a threat to prolonging working life in vulnerable groups in the labour market

Upregulated mRNA expression of desaturase and elongase, two enzymes involved in highly unsaturated fatty acids biosynthesis pathways during follicle maturation in zebrafish

<p>Abstract</p> <p>Background</p> <p>Although unsaturated fatty acids such as eicosapentaenoic acid (EPA, C20:5n-3), docosahexaenoic acid (DHA, C22:6n-3) and arachidonic acid (ARA, C20:4n-6), collectively known as the highly unsaturated fatty acids (HUFA), play pivotal roles in vertebrate reproduction, very little is known about their synthesis in the ovary. The zebrafish (Danio rerio) display capability to synthesize all three HUFA via pathways involving desaturation and elongation of two precursors, the linoleic acid (LA, C18:2n-6) and linolenic acid (LNA, C18:3n-3). As a prerequisite to gain full understanding on the importance and regulation of ovarian HUFA synthesis, we described here the mRNA expression pattern of two enzymes; desaturase (fadsd6) and elongase (elovl5), involved in HUFA biosynthesis pathway, in different zebrafish ovarian follicle stages. Concurrently, the fatty acid profile of each follicle stage was also analyzed.</p> <p>Methods</p> <p>mRNA levels of fadsd6 and elovl5 in different ovarian follicle stages were determined by semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) assays. For analysis of the ovarian follicular fatty acid composition, gas chromatography was used.</p> <p>Results</p> <p>Our results have shown that desaturase displayed significant upregulation in expression during the oocyte maturation stage. Expression of elongase was significantly highest in pre-vitellogenic follicles, followed by maturation stage. Fatty acid composition analysis of different ovarian follicle stages also showed that ARA level was significantly highest in pre-vitellogenic and matured follicles. DHA level was highest in both late vitellogenic and maturation stage.</p> <p>Conclusion</p> <p>Collectively, our findings seem to suggest the existence of a HUFA synthesis system, which could be responsible for the synthesis of HUFA to promote oocyte maturation and possibly ovulation processes. The many advantages of zebrafish as model system to understand folliculogenesis will be useful platform to further elucidate the regulatory and mechanism aspects of ovarian HUFA synthesis.</p