13 research outputs found

    A disk based stream oriented approach for storing big data

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    Abstract—This paper proposes an extension to the generally accepted definition of Big Data and from this extended definition proposes a specialized database design for storing high through-put data from low-latency sources. It discusses the challenges a financial company faces with regards to processing and storing data and how existing database technologies are unsuitable for this niche task. A prototype database called CakeDB is built using a stream oriented, disk based storage design and insert throughput tests are conducted to demonstrate how effectively such a design would handle high throughput data as per the use case. I

    Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

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    Dimethyl fumarate (DMF) inhibits inflammasome-mediated inflammation and has been proposed as a treatment for patients hospitalised with COVID-19. This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]), is assessing multiple treatments in patients hospitalised for COVID-19 (NCT04381936, ISRCTN50189673). In this assessment of DMF performed at 27 UK hospitals, adults were randomly allocated (1:1) to either usual standard of care alone or usual standard of care plus DMF. The primary outcome was clinical status on day 5 measured on a seven-point ordinal scale. Secondary outcomes were time to sustained improvement in clinical status, time to discharge, day 5 peripheral blood oxygenation, day 5 C-reactive protein, and improvement in day 10 clinical status. Between 2 March 2021 and 18 November 2021, 713 patients were enroled in the DMF evaluation, of whom 356 were randomly allocated to receive usual care plus DMF, and 357 to usual care alone. 95% of patients received corticosteroids as part of routine care. There was no evidence of a beneficial effect of DMF on clinical status at day 5 (common odds ratio of unfavourable outcome 1.12; 95% CI 0.86-1.47; p = 0.40). There was no significant effect of DMF on any secondary outcome

    Learn Raspberry Pi 2 with Linux and Windows 10

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    Learn Raspberry Pi with Linux

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    Learn Raspberry Pi with Linux

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    The definitive guide to MongoDB: the noSQL database for cloud and desktop computing

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    MongoDB, a cross-platform NoSQL database, is the fastest-growing new database in the world. MongoDB provides a rich document orientated structure with dynamic queries that you'll recognize from RDMBS offerings such as MySQL. In other words, this is a book about a NoSQL database that does not require the SQL crowd to re-learn how the database world works! MongoDB has reached 1.0 and already boasts 50,000+ users. The community is strong and vibrant and MongoDB is improving at a fast rate. With scalable and fast databases becoming critical for today's applications, this book shows you how to ins
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