TURISMO E A PRODUÇÃO DO ESPAÇO EM JOÃO PESSOA - PB

Este artigo fundamenta-se a partir das leituras de Henri Lefebvre. Dessa maneira, procura-se investigar as ações do poder público do Estado da Paraíba, frente ao turismo de sua capital. Objetivou-se com o trabalho verificar, por meio de levantamento bibliográfico, dados secundários, artigos científicos, revistas e jornais, as ações do Governo do Estado frente ao turismo. Nota-se que o mesmo entra como financiador de obras de grande magnitude em áreas que fortalecem ainda mais os investimentos do capital externo, refletindo no destino João Pessoa como receptáculo de um tipo de turismo voltado ao mercado, sem inserção e consulta da população local e pouca melhoria da condição de vida dos residentes.Palavras- chaves: Turismo. Produção do Espaço. Polo Turístico Cabo Branco- PB

REESTRUTURAÇÃO PRODUTIVA, TURISMO E INVESTIMENTOS INTERNACIONAIS NO LITORAL POTIGUAR

As políticas públicas de turismo possibilitaram a atração de investimentos turísticos privados para o Nordeste brasileiro, desencadeando uma intensa dinamização do mercado imobiliário ao longo da zona costeira. O objetivo do artigo é discutir os efeitos do processo de reestruturação produtiva no Rio Grande do Norte, a partir da análise da atividade turística, e suas implicações no mercado imobiliário no litoral potiguar. O foco da análise será o comércio de imóveis, decorrente dos investimentos internacionais no Polo Costa das Dunas. Com relação aos procedimentos metodológicos, a principal fonte de pesquisa foram os cartórios de imóveis dos municípios enfocados no presente estudo. A reestruturação produtiva propiciou a inserção mais efetiva do litoral potiguar no mercado globalizado, por meio de atividades ligadas ao turismo e ao lazer, desencadeando a compra de terras por investidores internacionais. Verificou-se que as corporações internacionais procuraram comprar imóveis cujo uso não está diretamente voltado para o lazer e nem para o turismo

Protocol for a Scoping Review Abstract

©Sílvia Rego, Ana Rita Henriques, Sofia Silvério Serra, Teresa Costa, Ana Maria Rodrigues, Francisco Nunes. Originally published in JMIR Research Protocols (https://www.researchprotocols.org), 26.10.2023.BACKGROUND: Clinical trials often use digital technologies to collect data continuously outside the clinic and use the derived digital endpoints as trial endpoints. Digital endpoints are also being developed to support diagnosis, monitoring, or therapeutic interventions in clinical care. However, clinical validation stands as a significant challenge, as there are no specific guidelines orienting the validation of digital endpoints. OBJECTIVE: This paper presents the protocol for a scoping review that aims to map the existing methods for the clinical validation of digital endpoints. METHODS: The scoping review will comprise searches from the electronic literature databases MEDLINE (PubMed), Scopus (including conference proceedings), Embase, IEEE (Institute of Electrical and Electronics Engineers) Xplore, ACM (Association for Computing Machinery) Digital Library, CENTRAL (Cochrane Central Register of Controlled Trials), Web of Science Core Collection (including conference proceedings), and Joanna Briggs Institute Database of Systematic Reviews and Implementation Reports. We will also include various sources of gray literature with search terms related to digital endpoints. The methodology will adhere to the Joanna Briggs Institute Scoping Review and the Guidance for Conducting Systematic Scoping Reviews. RESULTS: A search for reviews on the existing evidence related to this topic was conducted and has shown that no such review was previously undertaken. This review will provide a systematic assessment of the literature on methods for the clinical validation of digital endpoints and highlight any potential need for harmonization or reporting of methods. The results will include the methods for the clinical validation of digital endpoints according to device, digital endpoint, and clinical application goal of digital endpoints. The study started in January 2023 and is expected to end by December 2023, with results to be published in a peer-reviewed journal. CONCLUSIONS: A scoping review of methodologies that validate digital endpoints is necessary. This review will be unique in its breadth since it will comprise digital endpoints collected from several devices and not focus on a specific disease area. The results of our work should help guide researchers in choosing validation methods, identify potential gaps in the literature, or inform the development of novel methods to optimize the clinical validation of digital endpoints. Resolving these gaps is the key to presenting evidence in a consistent way to regulators and other parties and obtaining regulatory acceptance of digital endpoints for patient benefit. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/47119.publishersversionpublishe

Seed-Layer Free Zinc Tin Oxide Tailored Nanostructures for Nanoelectronic Applications: Effect of Chemical Parameters

POCI-01-0145-FEDER-007688Semiconductor nanowires are mostly processed by complex, expensive, and high temperature methods. In this work, with the intent of developing zinc tin oxide nanowires (ZTO NWs) by low-cost and low-complexity processes, we show a detailed study on the influence of chemical parameters in the hydrothermal synthesis of ZTO nanostructures at temperatures of only 200 degrees C. Two different zinc precursors, the ratio between zinc and tin precursors, and the concentration of the surfactant agent and of the mineralizer were studied. The type and the crystallinity of the nanostructures were found to be highly dependent on the used precursors and on the concentration of each reagent. Conditions for obtaining different ZTO nanostructures were achieved, namely, Zn2SnO4 nanoparticles and ZnSnO3 nanowires with length similar to 600 nm, with the latter being reported for the first time ever by hydrothermal methods without the use of seed layers. Optical and electrical properties were analyzed, obtaining band gaps of 3.60 and 3.46 eV for ZnSnO3 and Zn2SnO4, respectively, and a resistivity of 1.42 k Omega.cm for single ZnSnO3 nanowires, measured using nanomanipulators after localized deposition of Pt electrodes by e-beam assisted gas decomposition. The low-temperature hydrothermal methods explored here proved to be a low-cost, reproducible, and highly flexible route to obtain multicomponent oxide nanostructures, particularly ZTO NWs. The diversity of the synthesized ZTO structures has potential application in next-generation nanoscale devices such as field effect nanotransistors, nanogenerators, resistive switching memories, gas sensors, and photocatalysis.proofpublishe

Tourism and social capital: a theoretical and conceptual approach

As mudanças no modo de produção no século XX levaram o homem a modificar o seu modo de vida. Diante disso, o capital encontra mais uma forma de exploração econômica, o turismo. Analisa -se o turismo relacionando -o ao capital social, baseado em Putnam (2000) e paralelamente pesquisas bibliográficas de autores que analisam o tema. Tal objeto de pesquisa é incipiente, mostra amplo campo de investigação, valorizando o capital social como estratégico para o desenvolvimento local. Foram analisadas comunidades do litoral cearense, notademante a prainha do Canto Verde no município de Beberibe – CE. Com esta análise é possível vislumbrar a possibilidade de um turismo alternativo, que contraponha a exploração perversa e predatória tão comum em diversos destinos turísticos, especialmente no Nordeste brasileiro.The changes in the mode of production in the twentieth century led man to change their way of life. Thus, the capital found another form of economic exploitation, tourism. This paper analyzes the tourism relating to the social capital, based on Putnam (2000) and parallel literature searches of authors who analyze the issue. Such an object of research is in its begin, shows wide field of research, valuing the social capital as a strategic for the social development. We analyzed communities of Ceará, mainly the Prainha do Canto Verde Beberibe - CE. It is possible to envisage the possibility of an alternative tourism, which opposes the predatory exploitation commonly practiced in many tourist destinations, particularly in the Brazil Northeast

Potencialidades e fragilidades da educação a distância no contexto da atenção básica

A educação a distância como estratégia para o incremento das ações de alimentação e nutrição na atenção primária no SUS é o tema central desse artigo, com o objetivo de avaliar o processo de educação a distância para a promoção da segurança alimentar e nutricional no contexto da atenção básica. Os dados foram gerados a partir da interação dos educandos e tutores, categorizados a partir do referencial de análise de conteúdo, os resultados a luz da teoria da Problematização e apoiada pelo arcabouço teórico da Saúde Coletiva. Categorias de análise destacam-se: O processo educacional e o educando em ambiente virtual; O papel do tutor na modalidade de EAD: Ações intersetoriais e territorialização. Concluiu-se que a educação a distância é uma tecnologia que promove mudanças, quando utilizada para aproximar teoria e prática, ressignificar o trabalho e empoderar o educando para ações de transformação na atenção básic

Lack of detectable allergenicity of transgenic maize and soya samples

Background: The safety issues regarding foods derived from genetically modified (GM) plants are central to their acceptance into the food supply. The potential allergenicity of proteins newly introduced in GM foods is a major safety concern. Objective: We sought to monitor, in potentially sensitive human populations, the allergenicity effects of 5 GM materials obtained from sources with no allergenic potential and already under commercialization in the European Union. Methods: We have performed skin prick tests with protein extracts prepared from transgenic maize (MON810, Bt11, T25, Bt176) and soya (Roundup Ready) samples and from nontransgenic control samples in 2 sensitive groups: children with food and inhalant allergy and individuals with asthmarhinitis. We have also tested IgE immunoblot reactivity of sera from patients with food allergy to soya (Roundup Ready) and maize (MON810, Bt11, Bt176) samples, as well as to the pure transgenic proteins (CryIA[b] and CP4 5-enolpyruvylshikimate- 3-phosphate synthase). Results: None of the individuals undergoing tests reacted differentially to the transgenic and nontransgenic samples under study. None of the volunteers tested presented detectable IgE antibodies against pure transgenic proteins. Conclusion: The transgenic products under testing seem to be safe in terms of allergenic potential. We propose postmarket testing as an important screening strategy for putative allergic sensitization to proteins introduced in transgenic plants.Supported by Fundação Calouste Gulbenkian, research project SDH.SP.I.01.11 and by Comissão de Fomento da Investigação em Cuidados de Saúde, research project no. 186/0

Acorn flour as a source of bioactive compounds in gluten-free bread

Polyphenols are important bioactive compounds whose regular ingestion has shown di erent positive impacts in health. Celiac patients have nutritional deficiencies, bringing many problems to their health. Thus, it is important to develop gluten-free (GF) products, such as bread, with nutritional benefits. The acorn is the fruit of holm oak and cork oak, being an underexploited resource nowadays. Its nutritional and functional characteristics are remarkable: rich in unsaturated fatty acids and fiber, vitamin E, chlorophylls, carotenoids, phenolic compounds, and antioxidant properties. The purpose of this study was to assess the use of acorn flour as a bioactive compounds source and natural GF ingredient for baking GF bread. Bread loaves were prepared with buckwheat, rice, acorn flour, and potato starch. Two levels of acorn flour (23% and 35% of the flour mixture) were tested. The physical, nutritional, and sensory characteristics of the bread were analysed, as well as the composition of phenolic compounds: total phenols, ortho-diphenols, and flavonoids. The phenolic profile was assessed by Reverse Phase–High-Performance Liquid Chromatography–Diode Array Detector (RP-HPLC-DAD). The antioxidant activity of the bread extracts was determined by 2,2-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) diammonium salt (ABTS), diphenyl-1-picrylhidrazyl radical (DPPH), and ferric reducing antioxidant power (FRAP) methodologies. Acorn flour can be considered a good source of bioactive compounds and antioxidants in GF bread. Acorn flour showed good technological properties in GF baking, improving bread nutritional and sensory characteristicsinfo:eu-repo/semantics/publishedVersio

Protein hydrolysates from salmon heads and cape hake by-products: comparing enzymatic method with subcritical water extraction on bioactivity properties

Fish by-products can be converted into high-value-added products like fish protein hydrolysates (FPHs), which have high nutritional value and are rich in bioactive peptides with health benefits. This study aims to characterise FPHs derived from salmon heads (HPSs) and Cape hake trimmings (HPHs) using Alcalase for enzymatic hydrolysis and Subcritical Water Hydrolysis (SWH) as an alternative method. All hydrolysates demonstrated high protein content (70.4–88.7%), with the degree of hydrolysis (DH) ranging from 10.7 to 36.4%. The peptide profile of FPHs indicated the breakdown of proteins into small peptides. HPSs showed higher levels of glycine and proline, while HPHs had higher concentrations of glutamic acid, leucine, threonine, and phenylalanine. Similar elemental profiles were observed in both HPHs and HPSs, and the levels of Cd, Pb, and Hg were well below the legislated limits. Hydrolysates do not have a negative effect on cell metabolism and contribute to cell growth. HPSs and HPHs exhibited high 2,2′–azino-bis(3 ethylbenzthiazoline-6)-sulfonic acid (ABTS) radical scavenging activity, Cu2+ and Fe2+ chelating activities, and angiotensin-converting enzyme (ACE) inhibitory activity, with HPHs generally displaying higher activities. The α-amylase inhibition of both FPHs was relatively low. These results indicate that HPHs are a promising natural source of nutritional compounds and bioactive peptides, making them potential candidates for use as an ingredient in new food products or nutraceuticals. SWH at 250 °C is a viable alternative to enzymatic methods for producing FPHs from salmon heads with high antioxidant and chelating properties.info:eu-repo/semantics/publishedVersio

Hemoglobin concentration in children f rom birth to one year of age

Este estudo foi desenvolvido com o objetivo de descrever a evolução da concentração de hemoglobina [Hb], considerando os fatores: peso ao nascer; velocidade relativa de crescimento e alimentação. É um estudo transversal realizado com crianças no primeiro ano de vida, atendidas para acompanhamento do crescimento e do desenvolvimento em serviços públicos de saúde, em cidades localizadas nas cinco regiões geográficas brasileiras. Verificou-se que 51,7% das crianças entre 6 e 12 meses de idade eram anêmicas. A estimativa da Hb, por meio de uma equação teórica, sugeriu que o ferro endógeno permite manter os níveis normais de Hb no primeiro trimestre de vida. A prevalência de baixa Hb foi maior entre as crianças com baixo peso ao nascer. A velocidade relativa de crescimento, avaliada pela diferença do peso atual e peso ao nascer, em unidades de Z escore, não foi fator de relevância para a Hb. A importância do aleitamento materno foi evidente nos primeiros meses de vida. Verificou-se, entretanto, que os alimentos complementares não influenciaram a Hb. A elevada prevalência de níveis baixos de hemoglobina indica a necessidade de enfatizar programas de intervenção para o controle da anemia ferropriva. ______________________________________________________________________________________________________ ABSTRACTThis study aimed to describe the evolution of hemoglobin concentration considering the foll owing factors: b i rth weight, g rowth ra t e , a n d food intake. The cross-sectional study focused on infants (< 1 year of age) whose growth and d e velopment were monitored by public health s e rvices in cities located in the five geogra p h i c regions of Bra z i l . Some 51.7% of the childre n aged 6 to 12 months presented anemia. Es t imation of [Hb] concentration by a theore t i c a l equation suggested that endogenous iron is able to maintain normal Hb levels in the first t h ree months of life. Pre valence of reduced Hb was higher in low birth weight infants. Grow t h ra t e , verified by the difference between pre s e n t weight and birth weight in Z score s , was not the re l e vant factor for hemoglobin concentrat i o n . The re l e vance of breastfeeding was evident in the initial months of life. How e ve r, c o m p l e m e n t a ry foods did not influence infant Hb concentra t i o n . The high pre valence of low Hb levels calls attention to the need for prog rams to control anemia