311 research outputs found

    Multidimensional image selection and classification system based on visual feature extraction and scaling

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    Sorting and searching operations used for the selection of test images strongly affect the results of image quality investigations and require a high level of versatility. This paper describes the way that inherent image properties, which are known to have a visual impact on the observer, can be used to provide support and an innovative answer to image selection and classification. The selected image properties are intended to be comprehensive and to correlate with our perception. Results from this work aim to lead to the definition of a set of universal scales of perceived image properties that are relevant to image quality assessments. The initial prototype built towards these objectives relies on global analysis of low-level image features. A multidimensional system is built, based upon the global image features of: lightness, contrast, colorfulness, color contrast, dominant hue(s) and busyness. The resulting feature metric values are compared against outcomes from relevant psychophysical investigations to evaluate the success of the employed algorithms in deriving image features that affect the perceived impression of the images

    Analisi per patologia

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    Life cycle assessment and feasibility analysis of a combined chemical looping combustion and power-to-methane system for CO2 capture and utilization

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    The ability to store effectively excess of electrical energy from peaks of production is key to the development of renewable energies. Power-To-Gas, and specifically Power-To-Methane represents one of the most promising option. This works presents an innovative process layout that integrates Chemical Looping Combustion of solid fuels and a Power-to-Methane system. The core of the proposed layout is a multiple interconnected fluidized bed system (MFB) equipped with a two-stage fuel reactor (t-FR). Performances of the system were evaluated by considering a coal as fuel and CuO supported on zirconia as oxygen carrier. A kinetic scheme comprising both heterogeneous and homogeneous reactions occurring in the MFB was considered. The methanation unit was modelled developing a thermodynamic calculation method based on minimization of the free Gibbs energy. The performance of the system was evaluated by considering that the CO/CO2 stream coming from the t-FR reacts over Ni supported on alumina catalyst with a pure H2 stream generated by an array of electrolysis cells. The number of cells to be stacked in the array was evaluated by considering that a constant H2 production able to convert the whole CO/CO2 stream produced by the CLC process should be attained. The environmental performance of the proposed process was quantified using the Life Cycle Assessment (LCA) methodology. The analysis shows i) that the majority originate from the production and disposal of the oxygen carrier used in the t-FR, and ii) that reusing part of the oxygen produced by the electrolysis cells improves significantly the environmental performance of the proposed process

    Life cycle assessment and feasibility analysis of a combined chemical looping combustion and power-to-methane system for CO2 capture and utilization

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    The ability to store effectively excess of electrical energy from peaks of production is key to the development of renewable energies. Power-To-Gas, and specifically Power-To-Methane represents one of the most promising option. This works presents an innovative process layout that integrates Chemical Looping Combustion of solid fuels and a Power-to-Methane system. The core of the proposed layout is a multiple interconnected fluidized bed system (MFB) equipped with a two-stage fuel reactor (t-FR). Performances of the system were evaluated by considering a coal as fuel and CuO supported on zirconia as oxygen carrier. A kinetic scheme comprising both heterogeneous and homogeneous reactions occurring in the MFB was considered. The methanation unit was modelled developing a thermodynamic calculation method based on minimization of the free Gibbs energy. The performance of the system was evaluated by considering that the CO/CO2 stream coming from the t-FR reacts over Ni supported on alumina catalyst with a pure H2 stream generated by an array of electrolysis cells. The number of cells to be stacked in the array was evaluated by considering that a constant H2 production able to convert the whole CO/CO2 stream produced by the CLC process should be attained. The environmental performance of the proposed process was quantified using the Life Cycle Assessment (LCA) methodology. The analysis shows i) that the majority originate from the production and disposal of the oxygen carrier used in the t-FR, and ii) that reusing part of the oxygen produced by the electrolysis cells improves significantly the environmental performance of the proposed process

    Prevalenza della fibrillazione atriale, eleggibilità al trattamento e consumo di anticoagulanti orali nelle Aziende Sanitarie italiane: impatto dei nuovi anticoagulanti

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    Background. Atrial fibrillation (AF) increases significantly the risk of comorbidities and premature death. This paper aims to estimate: 1) the current prevalence of AF in Italy as a whole and within individual local health authorities (LHA); 2) the proportion of strongly eligible patients receiving oral anticoagulants; 3) the impact of non-vitamin K antagonist oral anticoagulants (NOACs). Methods. The prevalence of AF and the proportion of patients strongly eligible for anticoagulant treatment (defined by a CHADS2 score ≥2) were obtained by applying the results of a systematic literature search to the Italian population stratified by gender, age and LHA. The consumption of oral anticoagulants in eligible patients within each LHA was derived from Intercontinental Marketing Services data. Results. Altogether, the detected prevalence of AF in Italy is 1.7%, i.e. 1 036 448 cases. Of these, 62.6%, i.e. 648 832 subjects, are estimated to have a CHADS2 ≥2 and therefore strongly eligible for anticoagulant treatment. The estimated percentage of eligible treated patients in 2015 was 43.7%, significantly greater compared to 2014 (31.3%), with local and regional variabilities. In 2015 the estimated use of NOACs for AF was 36.4% of all oral anticoagulants, with marked local and regional variabilities. NOAC prescription appears influenced by financial limitations and by factors related to the network of anticoagulation services. Conclusions. The present analysis shows a prevalence of AF in Italy of 1.7%. The overall rate of anticoagulant use is increasing, but is still insufficient, with marked regional and local variations. In 2015, approximately one third of oral anticoagulation in eligible patients was based on NOACs

    Arterial hypertension in aortic valve stenosis: A critical update

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    Aortic stenosis (AS) is a very common valve disease and is associated with high mortality once it becomes symptomatic. Arterial hypertension (HT) has a high prevalence among patients with AS leading to worse left ventricle remodeling and faster degeneration of the valve. HT also interferes with the assessment of the severity of AS, leading to an underestimation of the real degree of stenosis. Treatment of HT in AS has not historically been pursued due to the fear of excess reduction in afterload without a possibility of increasing stroke volume due to the fixed aortic valve, but most recent evidence shows that several drugs are safe and effective in reducing BP in patients with HT and AS. RAAS inhibitors and beta‐blockers provide benefit in selected populations based on their profile of pharmacokinetics and pharmacodynamics. Different drugs, on the other hand, have proved to be unsafe, such as calcium channel blockers, or simply not easy enough to handle to be recommended in clinical practice, such as PDE5i, MRA or sodium nitroprusside. The present review highlights all available studies on HT and AS to guide antihypertensive treatment

    Preliminary assessment of persistent organic pollutants (POPs) in tissues of Risso's dolphin (Grampus griseus) specimens stranded along the Italian coasts

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    Ecotoxicological and pathological research on Grampus griseus (Cuvier, 1812) (Risso's dolphins) is scarce both globally and in the Mediterranean Sea. This species has been classified as "Vulnerable" by the International Union for Conservation of Nature (IUCN) in the Mediterranean Sea.To evaluate the presence of "persistent organic pollutants" (POPs), especially organochlorine compounds (OCs), in the animals, chemical analyses were performed on tissues and organs of Risso's dolphin stranded along the Italian coasts between 1998 and 2021. Toxic contaminants such as hexachlorobenzene (HCB), poly-chlorinated biphenyls (PCBs), dichlorodiphenyltrichloroethane and its metabolites (DDTs) were examined in the blubber, liver, muscle, and brain of 20 animals, and data was correlated with sex, age, and stranding locations

    CRHyME (Climatic Rainfall Hydrogeological Modelling Experiment): a new model for geo-hydrological hazard assessment at the basin scale

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    This work presents the new model called CRHyME (Climatic Rainfall Hydrogeological Modelling Experiment), a tool for geo-hydrological hazard evaluation. CRHyME is a physically based and spatially distributed model written in the Python language that represents an extension of the classic hydrological models working at the basin scale. CRHyME's main focus consists of simulating rainfall-induced geo-hydrological instabilities such as shallow landslides, debris flows, catchment erosion and sediment transport into a river. These phenomena are conventionally decoupled from a hydrological routine, while in CRHyME they are simultaneously and quantitatively evaluated within the same code through a multi-hazard approach. CRHyME is applied within some case studies across northern Italy. Among these, the Caldone catchment, a well-monitored basin of 27 km2 located near the city of Lecco (Lombardy), was considered for the calibration of solid-transport routine testing, as well as the spatial-scale dependence related to digital terrain resolution. CRHyME was applied across larger basins of the Valtellina (Alps) and Emilia (Apennines) areas (∼2600 km2) which have experienced severe geo-hydrological episodes triggered by heavy precipitation in the recent past. CRHyME's validation has been assessed through NSE (Nash–Sutcliffe efficiency) and RMSE (root mean square error) hydrological-error metrics, while for landslides the ROC (receiver operating characteristic) methodology was applied. CRHyME has been able to reconstruct the river discharge at the reference hydrometric stations located at the outlets of the basins to estimate the sediment yield at some hydropower reservoirs chosen as a reference and to individuate the location and the triggering conditions of shallow landslides and debris flows. The good performance of CRHyME was reached, assuring the stability of the code and a rather fast computation and maintaining the numerical conservativity of water and sediment balances. CRHyME has shown itself to be a suitable tool for the quantification of the geo-hydrological process and thus useful for civil-protection multi-hazard assessment.</p

    HEPATITIS C IS ASSOCIATED WITH HIGH LEVELS OF CIRCULATING N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE AND INTERLEUKIN-6

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    To our knowledge, no study has evaluated N-terminal pro-brain natriuretic peptide (NTproBNP) together with interleukin-6 (IL-6) and interferon (IFN)-gamma serum levels in a large series of patients with hepatitis C virus (HCV) as possible markers of cardiac dysfunction. NTproBNP and IL-6 serum levels were valued in 55 HCV-patients, and in 55 sex- and age-matched controls. HCV-patients showed significantly higher mean NTproBNP and IL-6 levels than controls (P= 0.001); no significant difference was observed for IFN-gamma. By defining high NTproBNP level as a value higher than 300 pg/mL (that is used to rule out heart failure in patients under 75 years of age), 12% (6/49) of HCV-patients and 0 of controls had NTproBNP (chi(2); P = 0.012). In conclusion, this study demonstrates high levels of circulating NTproBNP and IL-6 in HCV-patients. The increase of NTproBNP may indicate the presence of a subclinical cardiac dysfunction. Further prospective studies quantifying symptoms and correlating these with echocardiographic parameters are needed to confirm this association
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