Long-term changes in thyroid stump after operations for multinodular colloid goiter

The variants of «behavior» of thyroid stump in 108 patients undergoing the different kinds of operations for multinodular colloid goiter were analyzed. The evaluation of risk of recurrences of goiter was based on dynamic of ultrasound, Doppler, Hormonal examination of peripheral blood, morphological investigation. Hypertrophical type of changes of thyroid stump was revealed by 49,2% of patients after hemithyroidectomy and partial bilateral thyroidectomy (50% - volume resection) and 18,7% was revealed hypothyreosis. These morpho-functional changes associated with the iodine deficiency, poor ecological situation are presented as predictors of goiter's recurrence.Проанализированы варианты динамики состояния тиреоидного остатка после различных по объему операций по поводу многоузлового коллоидного зоба. У 49,2% больных, перенесших по поводу многоузлового коллоидного зоба экономные операции (гемитиреоидэктомию и двустороннюю резекция в объеме 50% железы) в течение года отмечаются изменения тиреоидного остатка по гипертрофическому типу, что в 18,7% случаев сопровождается послеоперационным гипотиреозом. На основании динамического изучения отдаленных данных УЗИ, допплеровского исследования, уровня тиреоидных гормонов и анализа результатов морфологических исследований проведена оценка возможности прогнозирования возникновения и течения «рецидива» заболевания

Greater Eurasia Project in the Context of Interdisciplinary Discourse

The article defines the basic methodological principles of the project “greater Eurasia”, involving the solution of the complex problems of the promotion of global security and sustainable world order in the “era of geopolitical tension” associated with the onset of “Globalization 2.0” at the initial stage of the sixth technological order, a revolutionary transition from “analog” to “digital era” at the beginning of the XXI century and the rethinking of anthropological values caused by the inclusion of the everyday life of modern human artificial intelligence — in the guise of an assistant, a controller of human behavior and actions, or a Chapek robot

A Search for Small-Scale Clumpiness in Dense Cores of Molecular Clouds

We have analyzed HCN(1-0) and CS(2-1) line profiles obtained with high signal-to-noise ratios toward distinct positions in three selected objects in order to search for small-scale structure in molecular cloud cores associated with regions of high-mass star formation. In some cases, ripples were detected in the line profiles, which could be due to the presence of a large number of unresolved small clumps in the telescope beam. The number of clumps for regions with linear scales of ~0.2-0.5 pc is determined using an analytical model and detailed calculations for a clumpy cloud model; this number varies in the range: ~2 10^4-3 10^5, depending on the source. The clump densities range from ~3 10^5-10^6 cm^{-3}, and the sizes and volume filling factors of the clumps are ~(1-3) 10^{-3} pc and ~0.03-0.12. The clumps are surrounded by inter-clump gas with densities not lower than ~(2-7) 10^4 cm^{-3}. The internal thermal energy of the gas in the model clumps is much higher than their gravitational energy. Their mean lifetimes can depend on the inter-clump collisional rates, and vary in the range ~10^4-10^5 yr. These structures are probably connected with density fluctuations due to turbulence in high-mass star-forming regions.Comment: 23 pages including 4 figures and 4 table

Selection of options for the reconstruction of the power supply system based on the fuzzy sets theory and the crit eria of decision-making theory

The article proposes a method for selecting options for the reconstruction of the power  supply  system  based  on  the  criteria  of  decision-making  theory.  The  reconstruction process  is  considered  as  a  sequential  game  with  two  players :  active  and  passive.  The probability of possible states of the system is determined on the basis of the fuzzy sets theory. The main criterion for the choice of the reconstruction option is the value of damage from the power  supply  interruption.  The  application  of  the  proposed  method  is  considered  on  the example of a large metallurgical enterprise

ANALYSIS OF CLINICAL CASES АНТИ-VEGF TREATMENT OF MASSIVE SUBRETINAL HEMORRHAGES COMPLICATING WET AGE-RELATED MACULAR DEGENERATION

Purpose. Analysis of clinical cases of anti-VEGF therapy (ranibizumab) in the treatment of wet age-related macular degeneration (AMD) complicated by massive subretinal hemorrhages of various sizes.Material and methods. A retrospective analysis of the results of treatment was performed in 18 patients with wet AMD complicated by massive subretinal hemorrhages, who received as a treatment three monthly intravitreal ranibizumab injections. The first group (10 eyes) included patients with hemorrhages ranging from 1.5 to 3 disc diameters (DD), the second group (8 eyes) – patients with subretinal hemorrhage area of up to 1.5 DD. The age of patients varied from 65 to 83 years. The study was conducted using visometry, ophthalmoscopy of the damaged eye and of the fellow eye, as well as a monthly photo-registration of fundus and the OCT of macular area. The examinations were carried out before the treatment and 1 month after each ranibizumab IVI conducted by the standard technology in a sterile operating room.Results. After 3 monthly ranibizumab IVI in 8 patients of the second group the ophthalmoscopy showed a complete resorption of subretinal blood already after the 2nd ranibizumab IVI. According to the OCT a normalization of anatomy in the macular area was noted. Visometry results and patients subjectively reported a gradual improvement in visual acuity in the course of treatment, in some cases up to a full recovery by the end of the third month of therapy. A pigment epithelial tear, passing through the foveal zone, was detected in the treatment process associated with resorption of submacular clumps in 9 of 10 patients of the first group with areas of subretinal hemorrhages more than 1.5 DD. A complete attachment and a recovery profile of the foveal zone were not observed in any patients even after the full course of anti-VEGF therapy. A total hemophthalmus developed in one eye in the postinjection period that required the vitrectomy surgery. The visual acuity in patients of the first group decreased from 0.3 to0.15 in the anti-VEGF therapy in the majority of cases. At the same time all patients reported a subjective improvement in the quality of vision – a reduction of the size and intensity of the central scotoma darkening due to a resorption of subretinal blood in the central area of the retina.Conclusion. The therapy with intravitreal injections of ranibizumab is indicated and effective in patients with hemorrhages more than 1.5 DD. anti-VEGF therapy leads to an improvement in the life quality of patients and facilitates their adaptation to a visual impairment, due to a total or partial resorption of subretinal blood and a reduction in the area and intensity of the central scotoma

Calculated and experimental evaluation heat pump distiller on pentane as working substance

One of the most common and reliable methods of water treatment is the method of thermal distillation. Despite the reliability of the method, its application is constrained by high energy intensity. The most effective way to reduce the cost of production of distillate is the use of thermal transformers, providing regenerate and heat recovery phase transformations of the distillate. The use of working fluid with the most favorable thermodynamic properties is of paramount importance for the creation of high efficiency thermotransformers. The work is considered working fluid for high-temperature heat pumps and the results of the calculation-experimental study of high-temperature vapor compression heat-pumping distiller on natural working substance n-pentan

Stoffaustausch während der Filmabsorption : Absorption von Ammoniak durch Wasser und Salzsäure

Untersucht wurde die Absorption von Ammoniak aus der Luft durch Wasser und Säure in einem einzelnen Kanal (Rohr mit berieselbaren Wänden) und in einem Turm mit Blechpaketeinsatz. In der Untersuchung wurde der Einfluß der Strömungsgeschwindigkeit, der Gasgeschwindigkeit und der Kanalabmessungen auf den allgemeinen und partiellen Absorptionskoeffizienten bestimmt