359 research outputs found
“Documentality” of the Collection “Dans la Steppe” in S. Persky’s Interpretation
The article is devoted to the analysis of the French collection “Dans la steppe” (1902), compiled and translated by S. M. Persky, which includes the following early stories of M. Gorky: “In the steppe”, “Grandfather Arkhip and Lyonka”, “Song of the Falcon”, “Emelyan Pilyai”, “The Khan and his son”, “Notch”, “Makar Chudra”, “Twenty-six and one”, “Old Woman Izergil”. Attention is paid to the preface of the collection written by Persky, in which he names facts from the life of the writer, thereby justifying the choice of stories and characterizing the main feature of the style of Gorky's early stories, manifested in the synthesis of documentary and artistic, namely, the description of the “autobiographical” space, the component of which is the image of the steppe. The author of the article dwells on the three most exhibitive in this aspect stories: “In the Steppe”, “Grandfather Arkhip and Lyonka”, “Emelyan Pilyai”. The author comes to the conclusion that Persky solves two primary tasks: first, the compiler of the collection acquaints the reader with the facts of Gorky's biography, and secondly, characterizes the author's style reflecting the transformation of the documentary style into the artistic one. It is shown that the collection, which includes stories arranged in a certain sequence, represents a story about the writer's search for his place in life
Comparison of two control programs of the VVER-1000 nuclear power unit using regression data mining models
A load-following mode of nuclear power plants (NPP) is a complicated procedure because there are significant changes in many interrelated processes. In order to show which control program (CP) of NPP is better to use, data mining (DM) techniques can be introduced. This study proposes a DM approach in order to show a possibility of using DM regression models for NPP. The datasets for DM were obtained by simulating two static CP of VVER-1000 NPP in Simulink software of Matlab program package.(undefined)info:eu-repo/semantics/publishedVersio
Experience with sustained-release melatonin for the treatment of sleep disorders in depression
The data available in the literature on the role of melatonin in the regulation of circadian rhythms and sleep disorders in the population and in patients with mental diseases are analyzed. The cause of insomnia may be circadian rhythm disorders due to the age-related decline in the elaboration of the endogenous hormones that are responsible for the quality and duration of sleep, one of which is melatonin.Sustained-release melatonin is a synthetic analogue of the endogenous human pineal hormone melatonin. According to clinical findings, the main proven clinical effects of sustained-release melatonin 2 mg are a reduction in the latency of sleep, improvement of its quality, and lack of daytime sleepiness. The drug causes no dependence on its long use and rebound symptoms (increased insomnia symptoms), positively affects cognitive functions, and lowers nocturnal blood pressure in hypertensive patients.The paper describes a clinical case of a female patient with recurrent depressive disorder, in whom sustained-release melatonin 2 mg has demonstrated high efficacy and good tolerability in the combination therapy of sleep disorders in the pattern of depression
Anomalies of Density, Stresses, and the Gravitational Field in the Interior of Mars
We determined the possible compensation depths for relief harmonics of
different degrees and orders. The relief is shown to be completely compensated
within the depth range of 0 to 1400 km. The lateral distributions of
compensation masses are determined at these depths and the maps are
constructed. The possible nonisostatic vertical stresses in the crust and
mantle of Mars are estimated to be 64 MPa in compression and 20 MPa in tension.
The relief anomalies of the Tharsis volcanic plateau and symmetric feature in
the eastern hemisphere could have arisen and been maintained dynamically due to
two plumes in the mantle substance that are enriched with fluids. The plumes
that originate at the core of Mars can arise and be maintained by the anomalies
of the inner gravitational field achieving +800 mGal in the region of plume
formation, - 1200 mGal above the lower mantle-core transition layer, and -1400
mGal at the crust.Comment: 9 pages, 5 figure
Cross-cultural study of attitudes to work of representativesof different age groups
Labor activity is the most important condition for self-development, life satisfaction and socialization. This article presents the results of research in the field of readiness for work, obtained in the Russian and Slovak empirical sample, which included University students, people under the retirement age (working and unemployed), working pensioners aged 55-65 years. The study also included students of secondary schools in order to identify factors that influence the formation of readiness for work.В данной статье представлены результаты исследований отношения к трудовой деятельности студентов вузов, людей, не достигших пенсионного возраста, трудящихся пенсионеров и учащихся общеобразовательных школ
SLOW QUASIKINETIC CHANGES IN WATER-LACTOSE COMPLEXES DURING STORAGE
Objective: To investigate kinetic changes in the spectral characteristics by Fourier Transform Infrared spectroscopy (FTIR) of water-lactose complexes (SMC), derived during the manufacturing process of the drug, containing release-active forms of antibodies.
Methods: lactose monohydrate substance, saturated with release-active forms of affinity-purified polyclonal rabbit antibodies to recombinant human interferon-gamma (RA forms of Abs); tablets produced from this substance by direct compression after the addition of excipients (microcrystalline cellulose, magnesium stearate). Powdered and tableted placebo samples saturated with technologically processed water or phosphate-buffered saline, as well as with intact ethanol were used as control. Kinetic changes in SMC were studied using an Agilent Cary 630 FTIR spectrophotometer with a diamond ATR accessory (Agilent Technologies, USA). We used the method of X-ray fluorescence spectroscopy (EDX-7000 Shimadzu energy dispersive X-ray fluorescence spectrometer) to track changes in the fluorescence signal at certain wavelengths. The range of measured elements–11Na-92U.
Results: Control of some technological characteristics of the obtained active substance (moisture, flowability) and dosage form (mean mass, disintegration rate) was used as indirect indicators of quality, but they did not allow reliably distinguishing intact lactose from the saturated one. Long-period oscillations on FTIR spectra were characteristic for all types of samples; oscillations occur at approximately two-week intervals; S/N indices were more stable for samples of RA forms of Abs than for placebo samples. On some days, the substance saturated with RA forms of Abs significantly differed from the intact lactose powder. The kinetics of the X-ray fluorescence intensity at certain wavelengths indicates the possibility of a periodic cooperative trigger transition of the system. Reversible conformational transitions are observed for powders on the 30th and 130th days (Kα 3.313 keV). For tablets at Kα 3.313 keV and Kα 1.740 keV small changes were visualized on those days (100–110th day) when hysteresis phenomena were recorded in the IR spectra of these samples.
Conclusion: As a result, the evidence for a long-period dramatic conformational mobility of the water-lactose complex was obtained. Based on the data on the semiannual kinetics of IR spectra, a universal criterion for the identity of lactose powder saturated with RA forms of Abs was obtained. Also, it was confirmed that the lactose conformation state was changed by saturation with RA forms of Abs
Properties of silicon dioxide layers with embedded metal nanocrystals produced by oxidation of Si:Me mixture
A two-dimensional layers of metal (Me) nanocrystals embedded in SiO2 were produced by pulsed laser deposition of uniformly mixed Si:Me film followed by its furnace oxidation and rapid thermal annealing. The kinetics of the film oxidation and the structural properties of the prepared samples were investigated by Rutherford backscattering spectrometry, and transmission electron microscopy, respectively. The electrical properties of the selected SiO2:Me nanocomposite films were evaluated by measuring C-V and I-V characteristics on a metal-oxide-semiconductor stack. It is found that Me segregation induced by Si:Me mixture oxidation results in the formation of a high density of Me and silicide nanocrystals in thin film SiO2 matrix. Strong evidence of oxidation temperature as well as impurity type effect on the charge storage in crystalline Me-nanodot layer is demonstrated by the hysteresis behavior of the high-frequency C-V curves
EPIDEMIOLOGICAL SITUATION OF DIPHTHERIA IN RUSSIA AND IN THE REGIONS OF THE RUSSIAN FEDERATION SINCE 2005 TO 2011
The analysis of the incidence of diphtheria in the Russian Federation after the second revaccination of adults since 2005 to 2011 is presented. The level of the immunization and. the state of population immunity were studied. The high level of protection against diphtheria was established. It provides positive epidemiological situation against this infection in the country
Comparison of Two Control Programs of the VVER-1000 Nuclear Power Unit Using Regression Data Mining Models
A load-following mode of nuclear power plants (NPP) is a complicated procedure because there are significant changes in many interrelated processes. In order to show which control program (CP) of NPP is better to use, data mining (DM) techniques can be introduced. This study proposes a DM approach in order to show a possibility of using DM regression models for NPP. The datasets for DM were obtained by simulating two static CP of VVER-1000 NPP in Simulink software of Matlab program package.Режим навантаження атомних електростанцій є складною процедурою, оскільки в багатьох взаємопов’язаних процесах відбуваються суттєві зміни. Для того щоб показати, яку програму керування (ПК) АЕС краще використовувати, треба запровадити методи інтелектуального аналізу даних (DM). У цьому дослідженні запропоновано підхід інтелектуального аналізу даних для демонстрації можливості використання моделей регресії до АЕС. Набори даних для DM отримано імітацією двох статичних ПК АЕС ВВЕР-1000 у програмному забезпеченні Simulink програмного пакету Matlab.Режим нагрузки атомных электростанций является сложной процедурой, поскольку во многих взаимосвязанных процессах происходят существенные изменения. Для того чтобы показать, какую программу управления (ПК) АЭС лучше использовать, нужно ввести методы интеллектуального анализа данных (DM). В этом исследовании предложен подход интеллектуального анализа данных для демонстрации возможности использования моделей регрессии к АЭС. Наборы данных для DM получены имитацией двух статических ПК АЭС ВВЭР-1000 в программном обеспечении Simulink программного пакета Matla
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